Search Results - "Pritzl, Curtis J"

Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1 by Xia, Chuan, Vijayan, Madhuvanthi, Pritzl, Curtis J, Fuchs, Serge Y, McDermott, Adrian B, Hahm, Bumsuk

“…Influenza A virus (IAV) employs diverse strategies to circumvent type I interferon (IFN) responses, particularly by inhibiting the synthesis of type I IFNs…”
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IKK2/NFkB signaling controls lung resident CD8+ T cell memory during influenza infection by Pritzl, Curtis J., Luera, Dezzarae, Knudson, Karin M., Quaney, Michael J., Calcutt, Michael J., Daniels, Mark A., Teixeiro, Emma

“…CD8 + T cell tissue resident memory (T RM ) cells are especially suited to control pathogen spread at mucosal sites. However, their maintenance in lung is…”
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Sphingosine kinase 1 serves as a pro-viral factor by regulating viral RNA synthesis and nuclear export of viral ribonucleoprotein complex upon influenza virus infection by Seo, Young-Jin, Pritzl, Curtis J, Vijayan, Madhuvanthi, Bomb, Kavita, McClain, Mariah E, Alexander, Stephen, Hahm, Bumsuk

“…Influenza continues to pose a threat to humans by causing significant morbidity and mortality. Thus, it is imperative to investigate mechanisms by which…”
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Interplay of Inflammatory, Antigen and Tissue-Derived Signals in the Development of Resident CD8 Memory T Cells by Pritzl, Curtis J., Daniels, Mark A., Teixeiro, Emma

“…CD8 positive, tissue resident memory T cells (T RM ) are a specialized subset of CD8 memory T cells that surveil tissues and provide critical first-line…”
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NFκB–Pim-1–Eomesodermin axis is critical for maintaining CD8 T-cell memory quality by Knudson, Karin M., Pritzl, Curtis J., Saxena, Vikas, Altman, Amnon, Daniels, Mark A., Teixeiro, Emma

“…T-cell memory is critical for long-term immunity. However, the factors involved in maintaining the persistence, function, and phenotype of the memory pool are…”
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STING controls T cell memory fitness during infection through T cell-intrinsic and IDO-dependent mechanisms by Quaney, Michael J, Pritzl, Curtis J, Luera, Dezzarae, Newth, Rebecca J, Knudson, Karin M, Saxena, Vikas, Guldenpfennig, Caitlyn, Gil, Diana, Rae, Chris S, Lauer, Peter, Daniels, Mark A, Teixeiro, Emma

“…Stimulator of interferon genes (STING) signaling has been extensively studied in inflammatory diseases and cancer, while its role in T cell responses to…”
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Sphingosine kinase 2 restricts T cell immunopathology but permits viral persistence by Studstill, Caleb J, Pritzl, Curtis J, Seo, Young-Jin, Kim, Dae Young, Xia, Chuan, Wolf, Jennifer J, Nistala, Ravi, Vijayan, Madhuvanthi, Cho, Yong-Bin, Kang, Kyung Won, Lee, Sang-Myeong, Hahm, Bumsuk

“…Chronic viral infections are often established by the exploitation of immune-regulatory mechanisms that result in nonfunctional T cell responses. Viruses that…”
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A ceramide analogue stimulates dendritic cells to promote T cell responses upon virus infections by Pritzl, Curtis J, Seo, Young-Jin, Xia, Chuan, Vijayan, Madhuvanthi, Stokes, Zachary D, Hahm, Bumsuk

“…The ceramide family of lipids plays important roles in both cell structure and signaling in a diverse array of cell types, including immune cells. However,…”
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Lactoferrin acts as an adjuvant during influenza vaccination of neonatal mice by Sherman, Michael P., Pritzl, Curtis J., Xia, Chuan, Miller, Mindy M., Zaghouani, Habib, Hahm, Bumsuk

“…Health policy precludes neonatal vaccination against influenza. Hence, morbidity and mortality are high under 6 months of age. Lactoferrin may activate…”
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Sphingosine analogue AAL-R increases TLR7-mediated dendritic cell responses via p38 and type I IFN signaling pathways by Seo, Young-Jin, Pritzl, Curtis J, Vijayan, Madhuvanthi, Blake, Celeste R, McClain, Mariah E, Hahm, Bumsuk

“…Sphingosine analogues display immunosuppressive activities and thus have therapeutic potential in the treatment of autoimmune diseases. In this study, we…”
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NF[kappa]B-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality by Knudson, Karin M, Pritzl, Curtis J, Saxena, Vikas, Altman, Amnon, Daniels, Mark A, Teixeiro, Emma

“…T-cell memory is critical for long-term immunity. However, the factors involved in maintaining the persistence, function, and phenotype of the memory pool are…”
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Sphingosine Kinase 2 mediates LCMV-induced CD4+ T cell suppression and instigates viral persistence while preventing immunopathology by Studstill, Caleb J, Pritzl, Curtis J., Seo, Young-Jin, Kim, Dae Y., Xia, Chuan Z., Wolf, Jennifer J, Vijayan, Madhuvanthi, Hahm, Bumsuk

“…Viruses often establish persistent infections by causing dysfunctional T cell responses. Little is known about the role of sphingosine kinase 2 (SphK2) in the…”
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Sphingosine Kinase 1 Serves as a Pro-Viral Factor by Regulating Viral RNA Synthesis and Nuclear Export of Viral Ribonucleoprotein Complex upon Influenza Virus Infection: e75005 by Seo, Young-Jin, Pritzl, Curtis J, Vijayan, Madhuvanthi, Bomb, Kavita, McClain, Mariah E, Alexander, Stephen, Hahm, Bumsuk

“…Influenza continues to pose a threat to humans by causing significant morbidity and mortality. Thus, it is imperative to investigate mechanisms by which…”
Get full text