Search Results - "Pritts, T. A."

Effects of whole blood leukoreduction on platelet function and hemostatic parameters by Morris, M. C., Veile, R., Friend, L. A., Oh, D., Pritts, T. A., Dorlac, W. C., Spinella, P. C., Goodman, M. D.

“…SUMMARY Aims/Objectives The aim of this study was to evaluate the hemostatic consequences of whole blood leukoreduction (LR). Background Whole blood is being…”
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Implementation of a clinical pathway decreases length of stay and cost for bowel resection by PRITTS, T. A, NUSSBAUM, M. S, FLESCH, L. V, FEGELMAN, E. J, PARIKH, A. A, FISCHER, J. E

“…To examine the effect of a clinical pathway for small and large bowel resection on cost and length of hospital stay. Clinical pathways are designed to…”
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Evaluation of endoscopic and laparoscopic training practices in surgical residency programs by MARKS, J. M, NUSSBAUM, M. S, PRITTS, T. A, SCHEERES, D. E

“…The ability to adequately train surgical residents in flexible and rigid endoscopy has become a difficult challenge for program directors. The American Board…”
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Induction of the stress response increases interleukin-6 production in the intestinal mucosa of endotoxaemic mice by Wang, Q, Sun, X, Pritts, T A, Wong, H R, Hasselgren, P O

“…Previous studies suggest that production of interleukin-6 (IL-6) is increased in the intestinal mucosa during sepsis and endotoxaemia. We tested the hypothesis…”
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Induction of the stress response in vivo decreases nuclear factor-kappa B activity in jejunal mucosa of endotoxemic mice by Pritts, T A, Wang, Q, Sun, X, Moon, M R, Fischer, D R, Fischer, J E, Wong, H R, Hasselgren, P O

“…Results of previous studies suggest that the stress response protects cells and tissues by regulating proinflammatory mediators. The transcription factor…”
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Proteasome Inhibitors Activate the Transcription Factors C/EBP-β and δ in Human Intestinal Epithelial Cells by Hungness, Eric S, Robb, Bruce W, Luo, Guang-ju, Pritts, Timothy A, Hershko, Dan D, Hasselgren, Per-Olof

“…In recent studies, induction of the heat shock response by hyperthermia upregulated the expression and DNA binding activity of the transcription factor C/EBP…”
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Complement Component C3 Production in IL-1β-Stimulated Human Intestinal Epithelial Cells Is Blocked by NF-κB Inhibitors and by Transfection with Ser 32/36 Mutant IκBα by Moon, M.Ryan, Parikh, Alexander A., Pritts, Timothy A., Fischer, Josef E., Cottongim, Sarah, Szabo, Csaba, Salzman, Andrew L., Hasselgren, Per-Olof

“…Background.Recent studies suggest that interleukin-1β (IL-1β) stimulates the production of the acute phase protein complement component C3 in human intestinal…”
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Intraoperative manometry to assess the esophagogastric junction during laparoscopic fundoplication and myotomy by Nussbaum, M S, Jones, M P, Pritts, T A, Fischer, D R, Wabnitz, B, Bondi, J

“…Surgery for gastroesophageal reflux disease and achalasia is performed to alleviate symptoms by improving esophagogastric junction (EGJ) function…”
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gamma delta T cells mitigate the organ injury and mortality of sepsis by Tsch sigma op, J, Martignoni, A, Goetzman, H S, Choi, L G, Wang, Q, Noel, J G, Ogle, C K, Pritts, T A, Johannigman, JA, Lentsch, AB, Caldwell, C C

“…Sepsis is a difficult condition to treat and is associated with a high mortality rate. Sepsis is known to cause a marked depletion of lymphocytes, although the…”
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Burn injuries in rats upregulate the gene expression of the ubiquitin-conjugating enzyme E2(14k) in skeletal muscle by Fang, C H, Sun, X, Li, B G, Fischer, D R, Pritts, T A, Penner, G, Hasselgren, P O

“…Burn injuries are associated with muscle cachexia, which mainly reflects protein breakdown in the ubiquitin-proteasome pathway. Ubiquitination of proteins…”
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The transcription factor activator protein-1 is activated and interleukin-6 production is increased in interleukin-1beta-stimulated human enterocytes by Hungness, E S, Pritts, T A, Luo, G J, Sun, X, Penner, C G, Hasselgren, P O

“…The intestinal mucosa is an active participant in the inflammatory and metabolic response to sepsis, endotoxemia, and other critical illness. The genes for…”
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Activation of NF-kappaB varies in different regions of the gastrointestinal tract during endotoxemia by Pritts, T A, Moon, M R, Wang, Q, Hungness, E S, Salzman, A L, Fischer, J E, Hasselgren, P O

“…The transcription nuclear factor-kappaB (NF-kappaB) regulates a large number of genes involved in the inflammatory response to sepsis and endotoxemia. We…”
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Interleukin-1beta induces complement component C3 and IL-6 production at the basolateral and apical membranes in a human intestinal epithelial cell line by Moon, M R, Parikh, A A, Pritts, T A, Kane, C, Fischer, J E, Salzman, A L, Hasselgren, P O

“…In previous studies, stimulation of cultured enterocytes with IL-1beta resulted in production of IL-6 and complement component C3. The cellular mechanisms of…”
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Transcription factors C/EBP-β and -δ regulate IL-6 production in IL-1β-stimulated human enterocytes by Hungness, Eric S., Luo, Guang-ju, Pritts, Timothy A., Sun, Xiaoyan, Robb, Bruce W., Hershko, Dan, Hasselgren, Per-Olof

“…In recent studies, treatment with IL‐1β of cultured Caco‐2 cells, a human intestinal epithelial cell line, resulted in transcriptional upregulation of IL‐6…”
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Dantrolene reduces serum TNFalpha and corticosterone levels and muscle calcium, calpain gene expression, and protein breakdown in septic rats by Fischer, D R, Sun, X, Williams, A B, Gang, G, Pritts, T A, James, J H, Molloy, M, Fischer, J E, Paul, R J, Hasselgren, P O

“…The effects of dantrolene on serum TNFalpha and corticosterone levels and on muscle calcium, calpain gene expression, and protein breakdown were studied in…”
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IL-1beta induction of NF-kappaB activation in human intestinal epithelial cells is independent of oxyradical signaling by Parikh, A A, Moon, M R, Pritts, T A, Fischer, J E, Szabó, C, Hasselgren, P O, Salzman, A L

“…IL-1beta stimulation of cultured epithelial cells induces the degradation of IkappaBalpha and the consequent nuclear translocation of NF-lambdaB, a critical…”
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Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells by Pritts, Timothy A, Hungness, Eric S, Hershko, Dan D, Robb, Bruce W, Sun, Xiaoyan, Luo, Guang-Ju, Fischer, Josef E, Wong, Hector R, Hasselgren, Per-Olof

“…In previous studies, the heat shock response, induced by hyperthermia or sodium arsenite, increased interleukin (IL)-6 production in intestinal mucosa and…”
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Stress response decreases the interleukin-1beta-induced production of complement component C3 in human intestinal epithelial cells by Moon, R, Pritts, T A, Parikh, A A, Fischer, J E, Salzman, A L, Ryan, M, Wong, H R, Hasselgren, P O

“…Interleukin-1beta (IL-1beta) increases the production of complement component C3 in enterocytes. Heat shock regulates the response to cytokines and other…”
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Use of omeprazole in the management of giant duodenal ulcer: Results of a prospective study by Fischer, David R., Nussbaum, Michael S., Pritts, Timothy A., Gilinsky, Norman H., Weesner, Robert E., Martin, Stephen P., Giannella, Ralph A.

“…Background: Giant duodenal ulcer (GDU) is generally thought to require surgical intervention. Proton pump inhibitors have beneficial effects in peptic ulcer…”
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Expression and binding activity of the glucocorticoid receptor are upregulated in septic muscle by Sun, Xiaoyan, Fischer, David R, Pritts, Timothy A, Wray, Curtis J, Hasselgren, Per-Olof

“…We examined the influence of sepsis, induced by cecal ligation and puncture in rats, on the protein and gene expression and hormone binding activity of the…”
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