Search Results - "Pritchard, Tracy J."

MicroRNA-320 Is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Heat-Shock Protein 20 by REN, Xiao-Ping, JINGHAI WU, XIAOHONG WANG, SARTOR, Maureen A, JIANG QIAN, JONES, Keith, NICOLAOU, Persoulla, PRITCHARD, Tracy J, FAN, Guo-Chang

“…Recent studies have identified critical roles for microRNAs (miRNAs) in a variety of cellular processes, including regulation of cardiomyocyte death. However,…”
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Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis by Pritchard, Tracy J., Kranias, Evangelia G.

“…Contractile dysfunction and ventricular arrhythmias associated with heart failure have been attributed to aberrant sarcoplasmic reticulum (SR) Ca 2+ cycling…”
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Stimulating Research Interest and Ambitions in Undergraduate Nursing Students: The Research-Doctorate Pipeline Initiative by Smith, Carolyn R, Martsolf, Donna S, Draucker, Claire Burke, Shambley-Ebron, Donna Z, Pritchard, Tracy J, Maler, Jeffrey

“…Background: Innovative strategies may support the Institute of Medicine's recommendation to increase the number of doctorally prepared nurses by 50% by 2020…”
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Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts by Pritchard, Tracy J, Kawase, Yoshiaki, Haghighi, Kobra, Anjak, Ahmad, Cai, Wenfeng, Jiang, Min, Nicolaou, Persoulla, Pylar, George, Karakikes, Ioannis, Rapti, Kleopatra, Rubinstein, Jack, Hajjar, Roger J, Kranias, Evangelia G

“…Impaired sarcoplasmic reticulum calcium cycling and depressed contractility are key characteristics in heart failure. Defects in sarcoplasmic reticulum…”
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Transgenic mice expressing Na+-K+-ATPase in smooth muscle decreases blood pressure by Pritchard, Tracy J, Parvatiyar, Michelle, Bullard, Daniel P, Lynch, Ronald M, Lorenz, John N, Paul, Richard J

“…The Na(+)-K(+)-ATPase (NKA) is a transmembrane protein that sets and maintains the electrochemical gradient by extruding three Na(+) in exchange for two K(+)…”
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Arterial α2-Na+ pump expression influences blood pressure: lessons from novel, genetically engineered smooth muscle-specific α2 mice by Chen, Ling, Song, Hong, Wang, Youhua, Lee, Jane C, Kotlikoff, Michael I, Pritchard, Tracy J, Paul, Richard J, Zhang, Jin, Blaustein, Mordecai P

“…Arterial myocytes express α1-catalytic subunit isoform Na(+) pumps (75-80% of total), which are ouabain resistant in rodents, and high ouabain affinity…”
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Small Heat Shock Protein 20 Interacts With Protein Phosphatase-1 and Enhances Sarcoplasmic Reticulum Calcium Cycling by Qian, Jiang, Vafiadaki, Elizabeth, Florea, Stela M, Singh, Vivek P, Song, Weizhong, Lam, Chi Kung, Wang, Yigang, Yuan, Qunying, Pritchard, Tracy J, Cai, Wenfeng, Haghighi, Kobra, Rodriguez, Patricia, Wang, Hong-Sheng, Sanoudou, Despina, Fan, Guo-Chang, Kranias, Evangelia G

“…BACKGROUND:Heat shock proteins (Hsp) are known to enhance cell survival under various stress conditions. In the heart, the small Hsp20 has emerged as a key…”
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Na(+)-K(+)-ATPase and Ca(2+) clearance proteins in smooth muscle: a functional unit by Pritchard, Tracy J, Bowman, Peggy Sue, Jefferson, Andrew, Tosun, Metiner, Lynch, Ronald M, Paul, Richard J

“…The Na(+)-K(+)-ATPase (NKA) can affect intracellular Ca(2+) concentration regulation via coupling to the Na(+)-Ca(2+) exchanger and may be important in…”
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Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias by Haghighi, Kobra, Pritchard, Tracy J, Liu, Guan-Sheng, Singh, Vivek P, Bidwell, Philip, Lam, Chi Keung, Vafiadaki, Elizabeth, Das, Parthib, Ma, Jianyong, Kunduri, Swati, Sanoudou, Despina, Florea, Stela, Vanderbilt, Erica, Wang, Hong-Shang, Rubinstein, Jack, Hajjar, Roger J, Kranias, Evangelia G

“…Abstract A hallmark of human and experimental heart failure is deficient sarcoplasmic reticulum (SR) Ca-uptake reflecting impaired contractile function. This…”
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Evaluation of a Summer Bridge: Critical Component of the Leadership 2.0 Program by Pritchard, Tracy J, Perazzo, Joseph D, Holt, Julie A, Fishback, Benjamin P, McLaughlin, Michaela, Bankston, Karen D, Glazer, Greer

“…Summer bridges facilitate the transition from high school to college. Although many schools employ summer bridges, few have published outcomes. This article's…”
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Basic Cardiovascular Sciences Conference 2009: Molecular Mechanisms of Cardiovascular Disease by Baines, Christopher P, Pritchard, Tracy J

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Na + ‐K + ATPase and Ca 2+ Clearance Proteins: A Coordinated Unit in Smooth Muscle? by Pritchard, Tracy J.

“…Abstract only Na + −K + ATPase (NKA) has been hypothesized to be involved in hypertension in part by influencing Ca 2+ handling via coupling to Na + −Ca 2+…”
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Leadership 2.0: Nursing's Next Generation: Lessons Learned on Increasing Nursing Student Diversity by Pritchard, Tracy, Glazer, Greer, Bankston, Karen, McGinnis, Kimberly

“…Colleges and universities are pivotal to successful efforts aimed at achieving greater nursing workforce diversity. In 2013, the College of Nursing at the…”
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Leadership Development and Interprofessional Nurse-Led Bedside Rounding Improves Nurse Leadership Self-Efficacy by Costanzo, Amy J., Gormley, Denise K., Hill-Clark, Jessica, Israel, Jahmeel, Goetz, Jane, Staubach, Katherine, Pritchard, Tracy J., Little, Myrna

“…Nurses with high self-efficacy are more engaged in interprofessional collaboration. The Bedside Nurse Leadership Development program, along with bedside nurses…”
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Abstract 34: A Human G109E Polymorphism in Inibitor-1 Compromises Cardiomyocyte Function and Induces Arrhythmias by Haghighi, Kobra, Pritchard, Tracy J, Singh, Vivek P, Das, Parthib, Vanderbilt, Erica L, Rubinstein, Jack, Kranias, Evangelia G

“…Abstract only Protein phosphatase 1 (PP1) has emerged as a nodal regulator of function and survival in the heart. Indeed, the increased activity of this enzyme…”
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Junctin and the histidine‐rich Ca 2+ binding protein: potential roles in heart failure and arrhythmogenesis by Pritchard, Tracy J., Kranias, Evangelia G.

“…Contractile dysfunction and ventricular arrhythmias associated with heart failure have been attributed to aberrant sarcoplasmic reticulum (SR) Ca 2+ cycling…”
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Abstract 19: Blood Pressure Correlates Directly with the Expression Level of High Ouabain Affinity a2 Na+ Pumps in Arterial Smooth Muscle by Chen, Ling, Song, Hong, Kotlikoff, Michael I, Lee, Jane, Pritchard, Tracy J, Paul, Richard J, Li, Meng, Blaustein, Mordecai P

“…Abstract only High ouabain affinity α2 Na + pumps are expressed in arterial smooth muscle (ASM). They help regulate blood pressure (BP) in several forms of…”
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The Small Heat Shock Protein 20 (Hsp20) Interacts with Protein Phosphatase-1 and Enhances Sarcoplasmic Reticulum Ca-Cycling by Qian, Jiang, Vafiadaki, Elizabeth, Florea, Stela M., Singh, Vivek P., Song, Weizhong, Lam, Chi Kung, Wang, Yigang, Yuan, Qunying, Pritchard, Tracy J., Cai, Wenfeng, Haghighi, Kobra, Rodriguez, Patricia, Wang, Hong-Sheng, Sanoudou, Despina, Fan, Guo-Chang, Kranias, Evangelia G.

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MicroRNA-320 is Involved in the Regulation of Cardiac Ischemia/Reperfusion Injury by Targeting Hsp20 by Ren, Xiao-Ping, Wu, Jinghai, Wang, Xiaohong, Sartor, Maureen A., Jones, Keith, Qian, Jiang, Nicolaou, Persoulla, Pritchard, Tracy J., Fan, Guo-Chang

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Regulation of Na+‐K+ ATPase (NKA) α‐isoforms and contractility in smooth muscle: evidence from transgenic mice by Pritchard, Tracy J., Bullard, Daniel P., Lynch, Ronald M., Paul, Richard J.

“…NKA is an enzyme that maintains Na+ and K+ gradients, and coupled to Na+‐Ca2+ exchange (NCX), modulates Ca2+ homeostasis. It has been hypothesized that the…”
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