Search Results - "Priscila S. Scheucher"

Direct comparison of flow-FISH and qPCR as diagnostic tests for telomere length measurement in humans by Gutierrez-Rodrigues, Fernanda, Santana-Lemos, Bárbara A, Scheucher, Priscila S, Alves-Paiva, Raquel M, Calado, Rodrigo T

“…Telomere length measurement is an essential test for the diagnosis of telomeropathies, which are caused by excessive telomere erosion. Commonly used methods…”
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The Combination of Gefitinib With ATRA and ATO Induces Myeloid Differentiation in Acute Promyelocytic Leukemia Resistant Cells by Almeida, Luciana Yamamoto de, Pereira-Martins, Diego A., Weinhäuser, Isabel, Ortiz, César, Cândido, Larissa A., Lange, Ana Paula, De Abreu, Nayara F., Mendonza, Sílvia E. S., de Deus Wagatsuma, Virgínia M., Do Nascimento, Mariane C., Paiva, Helder H., Alves-Paiva, Raquel M., Bonaldo, Camila C. O. M., Nascimento, Daniele C., Alves-Filho, José C., Scheucher, Priscila S., Lima, Ana Sílvia G., Schuringa, Jan Jacob, Ammantuna, Emanuele, Ottone, Tiziana, Noguera, Nelida I., Araujo, Cleide L., Rego, Eduardo M.

“…In approximately 15% of patients with acute myeloid leukemia (AML), total and phosphorylated EGFR proteins have been reported to be increased compared to…”
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Association between leukocyte telomere length and sex by quantile regression analysis by Gutierrez-Rodrigues, Fernanda, Alves-Paiva, Raquel M, Scatena, Natália F, Martinez, Edson Z, Scheucher, Priscila S, Calado, Rodrigo T

“…Telomere length (TL) is a biomarker of cellular proliferative history. In healthy individuals, leukocyte TL shortens with age and associates with the lifespan…”
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Eltrombopag preferentially expands haematopoietic multipotent progenitors in human aplastic anaemia by Quintino de Oliveira, Bruno, Catto, Luiz F. B., Santana, Bárbara A. A., Tellechea, M. Florencia, Scheucher, Priscila S., Scheinberg, Phillip, Calado, Rodrigo T.

“…Summary Eltrombopag has been added to first‐line treatment of immune aplastic anaemia (AA), resulting in higher responses. We analysed marrow samples of AA…”
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ABSENT CD33 IN AML PATIENTS: FROM DIAGNOSIS TO FOLLOW-UPS by Leticia O. Marani, Amanda Costa, Fernanda B. Silva, Maria Izabel A. Madeira, Priscila S. Scheucher, Josiane L.S. Schiavinato, Ana Silvia G. Lima, Katia B.B. Pagnano, Bruno K. Duarte, Sylvie Freeman, Eduardo M. Rego, Fabiola Traina, Lorena L. Figueiredo-Pontes

“…Background: Despite recent advances and development of new therapeutic targets and personalized medicine, acute myeloid leukemia (AML) treatment remains…”
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Linker for Activation of T-cell Family Member2 (LAT2) a Lipid Raft Adaptor Protein for AKT Signaling, Is an Early Mediator of Alkylphospholipid Anti-leukemic Activity by Thomé, Carolina H., dos Santos, Guilherme A., Ferreira, Germano A., Scheucher, Priscila S., Izumi, Clarice, Leopoldino, Andreia M., Simão, Ana Maria, Ciancaglini, Pietro, de Oliveira, Kleber T., Chin, Alice, Hanash, Samir M., Falcão, Roberto P., Rego, Eduardo M., Greene, Lewis J., Faça, Vitor M.

“…Lipid rafts are highly ordered membrane domains rich in cholesterol and sphingolipids that provide a scaffold for signal transduction proteins; altered raft…”
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ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype by Lucena-Araujo, Antonio R, Coelho-Silva, Juan L, Pereira-Martins, Diego A, Thomé, Carolina, Scheucher, Priscila S, Lange, Ana P, Paiva, Helder H, Hemmelgarn, Benjamin T, Morais-Sobral, Mariana C, Azevedo, Elisa A, Franca-Neto, Pedro L, Franca, Rafael F, Silva, Cleide L, Krause, Alexandre, Rego, Eduardo M

“…Here, we evaluated whether the overexpression of transcriptionally inactive ΔNp73 cooperates with PML/RARA fusion protein in the induction of an APL-leukemic…”
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Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia by Gimenes-Teixeira, Hamilton L, Lucena-Araujo, Antonio R, Dos Santos, Guilherme A, Zanette, Dalila L, Scheucher, Priscila S, Oliveira, Luciana C, Dalmazzo, Leandro F, Silva-Júnior, Wilson A, Falcão, Roberto P, Rego, Eduardo M

“…CD56 expression has been associated with a poor prognosis in lymphoid neoplasms, including T-cell acute lymphoblastic leukemia (T-ALL). MicroRNAs (miRNAs) play…”
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Imbalanced receptors, gene signatures, and function of NK subsets predicts poor clinical outcomes in AML by Costa, Amanda, Kuznetsova, Valeriya, Marani, Leticia O., Lopes, Izabela A., Binelli, Larissa S., Scheucher, Priscila S., Schiavinato, Josiane L., Madeira, Maria Isabel A., Pagnano, Katia B., Duarte, Bruno K., Glória, Ana Beatriz F., Rego, Eduardo M., Traina, Fabíola, Figueiredo-Pontes, Lorena L., Welner, Robert

“…Abstract NK cells mediate anti-leukemic immunosurveillance in AML. We hypothesized that impaired NK cells predict poor outcomes in AML. We analyzed the…”
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Dysregulated Activating and Inhibitory Receptors on Natural Killer Cells Predicts Immune Escape and Poor Outcomes in Acute Myeloid Leukemia by Costa, Amanda F O, Kuznetsova, Valeriya, Marani, Leticia O, Lopes, Izabela A, Binelli, Larissa S, Scheucher, Priscila S, Schiavinato, Josiane L, Faria, Joana T B, Madeira, Maria Isabel A, Pagnano, Katia B, Duarte, Bruno K, Gloria, Ana Beatriz F, Rego, Eduardo M, Traina, Fabiola, Welner, Robert, Figueiredo-Pontes, Lorena L

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Overexpression of KMT2E Is Associated with Higher Granulocytic Differentiation Rate in Response to ATRA-Based Treatment in Acute Promyelocytic Leukemia Cell Lines by Pereira-Martins, Diego Antonio, Weinhäuser, Isabel, Almeida, Luciana Yamamoto, De Deus Wagatsuma, Virginia Mara, Scheucher, Priscila S, Lucena-Araujo, Antonio R., Rego, Eduardo Magalhães

“…Introduction: In the clinical setting, low KMT2E expression has been associated with poor prognosis in both acute myeloid leukemia (Damm et al. J Clin Oncol…”
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Cytokine Profiles in Acute Promyelocytic Leukemia Patients at Diagnosis and during the Treatment with Acid All-Trans Retinoic and Anthracyclines by Almeida, Luciana Yamamoto, Scheucher, Priscila S, de Lima, Ana Silvia G, Bassi, Sarah C, Baggio, Márcia S, Weinhäuser, Isabel, Lange, Ana Paula, Pereira-Martins, Diego Antonio, Rego, Eduardo Magalhães

“…INTRODUCTION: Acute promyelocytic leukemia (APL) cells have been shown to secrete IL-1β, TNFα and IL-6 in vitro and particularly the first one has a relevant…”
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Stathmin 1 Is Highly Expressed in Acute Promyelocytic Leukemia and Microtubule Dynamics Is a Potential Target for ATRA-Resistant APL Cells by Machado-Neto, João Agostinho, Coelho-Silva, Juan Luiz, Lucena-Araujo, Antonio R., Scheucher, Priscila S, Melo, Raul Antônio Morais, Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia B B, Fagundes, Evandro Maranhão, Chauffaille, Maria de Lourdes, Chiattone, Carlos, Rego, Eduardo Magalhães, Traina, Fabiola

“…Introduction : Stathmin 1 is a microtubule destabilizer protein involved in the proliferation and differentiation of early hematopoietic progenitors. Aberrant…”
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Characterization Of Leukemic Stem Cells In AML Cell Lines Using ALDH Staining by Lira Benício, Mariana Tereza, Scheucher, Priscila S., Garcia, Aglair Bergamo, Falcao, Roberto P., Rego, Eduardo M.

“…The clinical significance of LSCs has recently been confirmed by the finding that stem cell-like gene expression signatures can predict the clinical outcome of…”
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Metformin Reduces Tumor Burden and Splenomegaly in JAK2V617F Murine Models by Machado-Neto, João Agostinho, Ribeiro, Renata Scopim, Coelho-Silva, Juan Luiz, Eide, Christopher A., Fenerich, Bruna Alves, Fernandes, Jaqueline Cristina, Alves, Ana Paula Nunes Rodrigues, Scheucher, Priscila S, Tognon, Cristina E., Figueiredo-Pontes, Lorena Lobo, Druker, Brian J., Rego, Eduardo Magalhães, Traina, Fabiola

“…Introduction : The recurrent gain-of-function JAK2V617F mutation confers growth factor-independent proliferation for hematopoietic cells and is a major…”
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The Transcripts Of Platelet-Endothelial Adhesion Molecules and Inflamatory Chemokine Activation Pathway Molecules Are Hyperexpressed In The Bone Marrow Of Acute Promyelocytic Leukemia Patients Presenting Severe Coagulopathy by Scheucher, Priscila S, dos Santos, Guilherme A., Panepucci, Rodrigo Alexandre, Goes de Araujo, Amelia, Falcao, Roberto P., Rego, Eduardo M.

“…Although Acute Promyelocytic Leukemia (APL) is now considered one of the most curable forms of acute leukemia, it is an aggressive disease associated with a…”
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Abstract A229: Mechanism of action of perifosine on the mantle cell lymphoma line, Granta-519 by Ferreira, Germano A., Thome, Carolina H., dos Santos, Guilherme A., Scheucher, Priscila S., Leopoldino, Andreia M., Simão, Ana M., Izume, Clarice, Panepucci, Rodrigo A., Ciancaglini, Pietro, Rego, Eduardo M., Faça, Vitor M., Greene, Lewis J.

“…Abstract Lipid rafts are highly ordered membrane domains that are enriched in cholesterol and sphingolipids and provides a scaffold for signal transduction…”
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Generation of Functional Regulatory T Cells From Umbilical Cord Blood Naïve T Cells: Potential Role of Hydroxymethylation in the Epigenetic Reprograming and Transcriptional Induction of FoxP3 by Haddad, Rodrigo, dos Santos Schiavinato, Josiane Lilian, Saldanha-Araújo, Felipe Saldanha, Scheucher, Priscila S, Araújo, Amélia G, Rego, Eduardo M., Covas, Dimas T, Zago, Marco A., Panepucci, Rodrigo Alexandre

“…Abstract 4835 The development and functionality of CD4+CD25hi regulatory T cells (Tregs) depends on stable FoxP3 expression, a central regulator of Treg…”
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Generation of Functional Regulatory T Cells From Umbilical Cord Blood Naïve T Cells: Potential Role of Hydroxymethylation in the Epigenetic Reprograming and Transcriptional Induction of FoxP3 by Haddad, Rodrigo, dos Santos Schiavinato, Josiane Lilian, Saldanha-Araújo, Felipe Saldanha, Scheucher, Priscila S, Araújo, Amélia G, Rego, Eduardo M., Covas, Dimas T, Zago, Marco A., Panepucci, Rodrigo Alexandre

“…Abstract Abstract 4835 The development and functionality of CD4+CD25hi regulatory T cells (Tregs) depends on stable FoxP3 expression, a central regulator of…”
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Caffeic Acid Phenetyl Ester, a Brazilian-Green-Propolis Derivative, Induces apoptosis in AML Cells, Promotes up Regulation of G-Protein Signaling and Hyper Secretion of IL-8 by Scheucher, Priscila S, Santos, Guilherme A dos, Teixeira, Hamilton L Gimenes, Thomé, Carolina H, Lucena-Araujo, Antonio R, Falcao, Roberto P., Rego, Eduardo M.

“…Abstract 3274 Propolis is a generic name for an adhesive resin collected, processed and used by bees to plug gaps, smooth internal walls and protect the…”
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