Consensus report on the use of PN‐HPT™ (polynucleotides highly purified technology) in aesthetic medicine

Consensus report on the use of PN‐HPT™ (polynucleotides highly purified technology) in aesthetic medicine

Background Injective procedures using polynucleotides‐based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified polynucleotides. The goal of this doc...

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Bibliographic Details
Published in:Journal of cosmetic dermatology Vol. 20; no. 3; pp. 922 - 928
Main Authors: Cavallini, Maurizio, Bartoletti, Emanuele, Maioli, Laura, Massirone, Alberto, Pia Palmieri, Isabella, Papagni, Marco, Priori, Maurizio, Trocchi, Gloria
Format: Journal Article
Language:English
Published: England John Wiley and Sons Inc 01-03-2021
Subjects:
Consensus
Cosmetic Techniques
Dermatologic Surgery
Esthetics
Humans
Hyaluronic Acid
Original Contribution
PN‐HPT
Polynucleotides
polynucleotides highly purified technology
Rejuvenation
Skin Aging
skin priming
skin rejuvenation
Technology
PN-HPT
polynucleotides
skin priming
polynucleotides highly purified technology
skin rejuvenation
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Summary:Background Injective procedures using polynucleotides‐based products to promote dermal rejuvenation and revitalization are steadily evolving, yet no structured protocols are available that discuss and provide guidance in aesthetic treatments with highly purified polynucleotides. The goal of this document was to provide consensus‐based recommendations for the safe and effective use of Polynucleotides Highly Purified Technology™ (PN‐HPT™) devices for skin rejuvenation. Patients/Methods A team of eight experts with extensive experience in treatments for skin rejuvenation and revitalization integrated the best available evidence and clinical judgment and devised a series of practical guidance to support dermatologists, plastic surgeons, and aesthetic physician in the use of PN‐HPT™ products, alone and in combination, in aesthetic medicine. Results For most items, the expert group achieved a majority consensus. “Recommendations” (consensus >80%) were reached for the face, periocular area, décolleté and neck, hands, scalp, and stretch marks. Recommendations include details of techniques, information on dosage, volumes to be injected, and the ideal number of required treatment sessions, as well as time intervals between them for different areas of face and body. A lower agreement level of 60% was reached on but one item related to the initial treatment cycle for the face, leading to a “Consensus statement” for that area instead of a full “Recommendation.” Conclusion The expert consensus illustrates the value of natural‐origin, highly purified polynucleotides (PN‐HPT™) as biostimulatory booster strategy for skin priming and revitalization of face and body and provides a detailed guide for the use.
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ISSN:1473-2130
1473-2165
DOI:10.1111/jocd.13679