Search Results - "Prins, Jolanda"

Triple reuptake inhibitors for treating subtypes of major depressive disorder: the monoamine hypothesis revisited by Prins, Jolanda, Olivier, Berend, Korte, S Mechiel

“…Major depression is one of the most prevalent forms of mental illnesses and is among the leading causes of disability, affecting about 121 million people…”
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Environmental enrichment induces behavioral recovery and enhanced hippocampal cell proliferation in an antidepressant-resistant animal model for PTSD by Hendriksen, Hendrikus, Prins, Jolanda, Olivier, Berend, Oosting, Ronald S

“…Post traumatic stress disorder (PTSD) can be considered the result of a failure to recover after a traumatic experience. Here we studied possible protective…”
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Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors by Blits, Bas, Derks, Sanne, Twisk, Jaap, Ehlert, Erich, Prins, Jolanda, Verhaagen, Joost

“…Recombinant adeno-associated viral vectors (AAVs) are very promising gene transfer tools for the nervous system. We have compared the efficiency of gene…”
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Lipopolysaccharide-induced anhedonia is abolished in male serotonin transporter knockout rats: An intracranial self-stimulation study by van Heesch, Floor, Prins, Jolanda, Konsman, Jan Pieter, Westphal, Koen G.C, Olivier, Berend, Kraneveld, Aletta D, Korte, S. Mechiel

“…Highlight ► LPS-induced anhedonia is abolished in SERT−/− rats, suggesting that increased activity of SERT during inflammation plays a role in the development…”
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The 5-HT1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and “waiting” impulsivity, but increases “stopping” impulsivity by Korte, S. Mechiel, Prins, Jolanda, Van den Bergh, Filip S., Oosting, Ronald S., Dupree, Rudy, Korte-Bouws, Gerdien A.H., Westphal, Koen G.C., Olivier, Berend, Denys, Damiaan A., Garland, Alexis, Güntürkün, Onur

“…The 5-HT1A/1B-receptor agonist eltoprazine has a behavioral drug signature that resembles that of a variety of psychostimulant drugs, despite the differences…”
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The many different faces of major depression: It is time for personalized medicine by Korte, S. Mechiel, Prins, Jolanda, Krajnc, Anne M., Hendriksen, Hendrikus, Oosting, Ronald S., Westphal, Koen G., Korte-Bouws, Gerdien A.H., Olivier, Berend

“…First line antidepressants are the so-called SSRIs (selective serotonin reuptake inhibitors), e.g. fluvoxamine, fluoxetine, sertraline, paroxetine and…”
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Lipopolysaccharide increases degradation of central monoamines: An in vivo microdialysis study in the nucleus accumbens and medial prefrontal cortex of mice by van Heesch, Floor, Prins, Jolanda, Konsman, Jan Pieter, Korte-Bouws, Gerdien A.H., Westphal, Koen G.C., Rybka, Joanna, Olivier, Berend, Kraneveld, Aletta D., Korte, S. Mechiel

“…Peripheral administration of lipopolysaccharide (LPS) in rodents induces anhedonia, i.e. the inability to experience pleasure. Recently, we reported that…”
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Systemic tumor necrosis factor-alpha decreases brain stimulation reward and increases metabolites of serotonin and dopamine in the nucleus accumbens of mice by van Heesch, Floor, Prins, Jolanda, Korte-Bouws, Gerdien A.H., Westphal, Koen G.C., Lemstra, Suzanne, Olivier, Berend, Kraneveld, Aletta D., Korte, S. Mechiel

“…•Peripherally injected TNF-alpha induces anhedonia in mice.•Accumbal extracellular 5-HIAA levels increase in response to peripheral TNF-alpha.•Accumbal…”
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The triple reuptake inhibitor DOV 216,303 induces long-lasting enhancement of brain reward activity as measured by intracranial self-stimulation in rats by Prins, Jolanda, Kenny, Paul J., Doomernik, Ivo, Schreiber, Rudy, Olivier, Berend, Mechiel Korte, S.

“…Triple reuptake inhibitors (TRIs) are potential new antidepressants, which not only enhance brain serotonin and norepinephrine concentrations but also increase…”
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On the origin of allostasis and stress-induced pathology in farm animals: Celebrating Darwin’s legacy by Korte, S. Mechiel, Prins, Jolanda, Vinkers, Christiaan H., Olivier, Berend

“…Darwin’s largest contribution to science is without doubt the mechanism of natural selection, an evolutionary game with players, strategies, and pay-offs. Game…”
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The novel triple reuptake inhibitor JZAD-IV-22 exhibits an antidepressant pharmacological profile without locomotor stimulant or sensitization properties by Caldarone, Barbara J, Paterson, Neil E, Zhou, Jia, Brunner, Daniela, Kozikowski, Alan P, Westphal, Koen G C, Korte-Bouws, Gerdien A H, Prins, Jolanda, Korte, S Mechiel, Olivier, Berend, Ghavami, Afshin

“…Triple reuptake inhibitors (TRIs) that block the dopamine transporter (DAT), norepinephrine transporter, and serotonin transporter are being developed as a new…”
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The putative antidepressant DOV 216,303, a triple reuptake inhibitor, increases monoamine release in the prefrontal cortex of olfactory bulbectomized rats by Prins, Jolanda, Denys, Damiaan A., Westphal, Koen G., Korte-Bouws, Gerdien A., Quinton, Maria S., Schreiber, Rudy, Groenink, Lucianne, Olivier, Berend, Korte, S. Mechiel

“…The first line of antidepressant treatment nowadays are selective serotonin reuptake inhibitors. Although they are relatively safe to use, selective serotonin…”
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The 5-HT 1A/1B -receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and "waiting" impulsivity, but increases "stopping" impulsivity by Korte, S Mechiel, Prins, Jolanda, Van den Bergh, Filip S, Oosting, Ronald S, Dupree, Rudy, Korte-Bouws, Gerdien A H, Westphal, Koen G C, Olivier, Berend, Denys, Damiaan A, Garland, Alexis, Güntürkün, Onur

“…The 5-HT -receptor agonist eltoprazine has a behavioral drug signature that resembles that of a variety of psychostimulant drugs, despite the differences in…”
Get full text