Search Results - "Prins, John"

Clinical review: adiponectin biology and its role in inflammation and critical illness by Robinson, Katherine, Prins, John, Venkatesh, Bala

“…Adiponectin is an adipokine first described just over a decade ago. Produced almost exclusively by adipocytes, adiponectin circulates in high concentrations in…”
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119-LB: Targeted IL-22 Improves Glucose Tolerance and Reduces Hepatic Steatosis and Hepatic Fibrosis in Murine Models of Diabetes and Liver Disease by PRINS, JOHN B., SAJIIR, HARESSH, KESHVARI, SAHAR, WONG, KUAN YAU, LOCKETT, JACK, MCGUCKIN, MICHAEL, HASNAIN, SUMAIRA Z.

“…The cytokine interleukin-22 (IL-22) is an inhibitor of cellular stress. In HFD murine models, systemic IL-22 is efficacious to restore glucose tolerance,…”
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Quantitative Proteomic Analysis Revealed N′‑Nitrosonornicotine-induced Down-regulation of Nonmuscle Myosin II and Reduced Cell Migration in Cultured Human Skin Fibroblast Cells by Prins, John M, Wang, Yinsheng

“…The association of tobacco smoke with decreased cell motility and wound healing is well documented; however, the cellular mechanisms and specific toxic tobacco…”
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Prevalence of osteoporosis in prostate cancer survivors: a meta-analysis by Lassemillante, Annie-Claude M., Doi, Suhail A. R., Hooper, John D., Prins, John B., Wright, Olivia R. L.

“…Androgen deprivation therapy (ADT), which is used in the treatment of prostate cancer (PCa), is associated with increased morbidity. Severe bone loss is a…”
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Cd2+-Induced Alteration of the Global Proteome of Human Skin Fibroblast Cells by Prins, John M, Fu, Lijuan, Guo, Lei, Wang, Yinsheng

“…Cadmium (Cd2+) is a toxic heavy metal and a well-known human carcinogen. The toxic effects of Cd2+ on biological systems are diverse and thought to be exerted…”
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Mass Spectrometric Analyses of Organophosphate Insecticide Oxon Protein Adducts by Thompson, Charles M., Prins, John M., George, Kathleen M.

“…Objective: Organophosphate (OP) insecticides continue to be used to control insect pests. Acute and chronic exposures to OP insecticides have been documented…”
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Quantitative Proteomic Analysis Revealed 4-(Methylnitrosamino)-1-(3-pyridinyl)-1-butanone-Induced Up-Regulation of 20S Proteasome in Cultured Human Fibroblast Cells by Prins, John M, Wang, Yinsheng

“…The tobacco-specific N-nitrosamine, 4-(methylnitrosamino)-1-(3-pyridinyl)-1-butanone (NNK), is a well-known carcinogen. Although the ability of the…”
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Diabetes screen during tuberculosis contact investigations highlights opportunity for new diabetes diagnosis and reveals metabolic differences between ethnic groups by Restrepo, Blanca I., Kleynhans, Léanie, Salinas, Alejandra B., Abdelbary, Bassent, Tshivhula, Happy, Aguillón-Durán, Genesis P., Kunsevi-Kilola, Carine, Salinas, Gloria, Stanley, Kim, Malherbe, Stephanus T., Maasdorp, Elizna, Garcia-Viveros, Moncerrato, Louw, Ilze, Garcia-Oropesa, Esperanza M., Lopez-Alvarenga, Juan Carlos, Prins, John B., Walzl, Gerhard, Schlesinger, Larry S., Ronacher, Katharina

“…Type 2 diabetes (T2D) is a prevalent risk factor for tuberculosis (TB), but most studies on TB-T2D have focused on TB patients, been limited to one community,…”
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Decreased Expression of the Voltage-Dependent Anion Channel in Differentiated PC-12 and SH-SY5Y Cells Following Low-Level Pb Exposure by Prins, John M., Park, Sunyoung, Lurie, Diana I.

“…Lead (Pb) has been shown to disrupt cellular energy metabolism, which may underlie the learning deficits and cognitive dysfunctions associated with…”
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Prevalence of osteoporosis in prostate cancer survivors II: a meta-analysis of men not on androgen deprivation therapy by Lassemillante, Annie-Claude M., Doi, Suhail A. R., Hooper, John D., Prins, John B., Wright, Olivia R. L.

“…The prevalence of osteoporosis in men with prostate cancer (PCa) on androgen deprivation therapy (ADT) is well documented, with up to 53 % affected by this…”
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Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs by Keane, Fiona M., Yao, Tsun-Wen, Seelk, Stefanie, Gall, Margaret G., Chowdhury, Sumaiya, Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Wu, Wengen, Farrell, Penny, Vieira de Ribeiro, Ana Julia, Osborne, Brenna, Yu, Denise M.T., Seth, Devanshi, Rahman, Khairunnessa, Haber, Paul, Topaloglu, A. Kemal, Wang, Chuanmin, Thomson, Sally, Hennessy, Annemarie, Prins, John, Twigg, Stephen M., McLennan, Susan V., McCaughan, Geoffrey W., Bachovchin, William W., Gorrell, Mark D.

“…The protease fibroblast activation protein (FAP) is a specific marker of activated mesenchymal cells in tumour stroma and fibrotic liver. A specific, reliable…”
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The metabolic syndrome in critically ill patients by Robinson, Katherine, MBBS, Kruger, Peter, MBBS, FANZCA, FCICM, Prins, John, MBBS, FRACP, PhD, Venkatesh, Bala, MBBS, FRCA, MD, FCICM

“…Metabolic support in intensive care is a rapidly evolving field with new information being gathered almost on a daily basis. In endocrine practice, over the…”
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Oxidative stress resulting from exposure of a human salivary gland cells to paraoxon: An in vitro model for organophosphate oral exposure by Prins, John M., Chao, Chih-Kai, Jacobson, Saskia M., Thompson, Charles M., George, Kathleen M.

“…Paraoxon exposure induces superoxide formation in human salivary gland cells at 4h as determined by fluorescence assay (dihydroethidium). •Human salivary gland…”
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Thionate versus Oxon: Comparison of Stability, Uptake, and Cell Toxicity of (14CH3O)2-Labeled Methyl Parathion and Methyl Paraoxon with SH-SY5Y Cells by Bharate, Sandip B, Prins, John M, George, Kathleen M, Thompson, Charles M

“…The stability, hydrolysis, and uptake of the organophosphates methyl parathion and methyl paraoxon were investigated in SH-SY5Y cells. The stabilities of…”
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Sialic Acid Modification of Adiponectin Is Not Required for Multimerization or Secretion but Determines Half-Life in Circulation by Richards, Ayanthi A, Colgrave, Michelle L, Zhang, Jialiang, Webster, Julie, Simpson, Fiona, Preston, Elaine, Wilks, Donna, Hoehn, Kyle L, Stephenson, Matthew, Macdonald, Graeme A, Prins, John B, Cooney, Gregory J, Xu, Aimin, Whitehead, Jonathan P

“…Adiponectin is an adipocyte-secreted, insulin-sensitizing hormone the circulating levels of which are reduced in conditions of insulin resistance and diabetes…”
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Lead exposure during development results in increased neurofilament phosphorylation, neuritic beading, and temporal processing deficits within the murine auditory brainstem by Jones, Linda G., Prins, John, Park, Sunyoung, Walton, Joseph P., Luebke, Anne E., Lurie, Diana I.

“…Low‐level lead (Pb) exposure is a risk factor for learning disabilities, attention deficit hyperactivity disorder (ADHD), and other neurological dysfunction…”
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Chronic low-level Pb exposure during development decreases the expression of the voltage-dependent anion channel in auditory neurons of the brainstem by Prins, John M., Brooks, Diane M., Thompson, Charles M., Lurie, Diana I.

“…Lead (Pb) exposure is a risk factor for neurological dysfunction. How Pb produces these behavioral deficits is unknown, but Pb exposure during development is…”
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Paraoxon-Induced Protein Expression Changes to SH-SY5Y Cells by Prins, John M, George, Kathleen M, Thompson, Charles M

“…SH-SY5Y neuroblastoma cells were examined to determine changes in protein expression following exposure to the organophosphate paraoxon…”
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Osteoporosis-Related Health Behaviors in Men With Prostate Cancer and Survivors: Exploring Osteoporosis Knowledge, Health Beliefs, and Self-Efficacy by Lassemillante, Annie-Claude M., Skinner, Tina L., Hooper, John D., Prins, John B., Wright, Olivia R. L.

“…This descriptive study aimed to (a) determine the extent of osteoporosis knowledge, perceived health beliefs, and self-efficacy with bone healthy behaviors in…”
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Adiponectin is associated with cardiovascular disease in male renal transplant recipients: baseline results from the LANDMARK 2 study by Kaisar, Mohd O, Armstrong, Kirsty, Hawley, Carmel, Campbell, Scott, Mudge, David, Johnson, David W, Prins, John B, Isbel, Nicole M

“…Adiponectin is a major adipocyte-derived protein with insulin-sensitizing, anti-inflammatory and anti-atherogenic properties. Adiponectin levels correlate…”
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