Search Results - "Princen, K"
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iPSC-derived cortical neurons to study sporadic Alzheimer disease: A transcriptome comparison with post-mortem brain samples
Published in Toxicology letters (01-03-2022)“…•The transcriptome of iPSC-derived cortical neurons and brain biopsies were assessed.•sAD iPSC-derived neurons & brain samples showed many similar AD-related…”
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A double-blind randomized placebo-controlled study on the clinical and microbial effects of an essential oil mouth rinse used by patients in supportive periodontal care
Published in International journal of dental hygiene (01-02-2013)“…Aim This 3‐month double‐blind randomized placebo‐controlled study evaluated the clinical and microbial effects of an essential oil mouth rinse used as an…”
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Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4
Published in FEBS letters (11-09-2002)“…This study was undertaken to demonstrate the unique specificity of the chemokine receptor CXCR4 antagonist AMD3100. Calcium flux assays with selected…”
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HIV chemokine receptor inhibitors as novel anti-HIV drugs
Published in Cytokine & growth factor reviews (01-12-2005)“…The chemokine receptors CXCR4 and CCR5 are the main coreceptors used by the T-cell-tropic (CXCR4-using, X4) and macrophage-tropic (CCR5-using, R5) HIV-1…”
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Mannose-Specific Plant Lectins from the Amaryllidaceae Family Qualify as Efficient Microbicides for Prevention of Human Immunodeficiency Virus Infection
Published in Antimicrobial Agents and Chemotherapy (01-10-2004)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor
Published in Biochemical pharmacology (01-09-2005)“…The chemokine receptors CCR5 and CXCR4 function as coreceptors for human immunodeficiency virus (HIV) and are attractive targets for the development of…”
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CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro
Published in AIDS (London) (05-11-2004)“…To evaluate the anti-HIV-1 activity of the cyclotriazadisulfonamide CADA against primary isolates in vitro and the combination of CADA with approved anti-HIV…”
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Inhibition of Human Immunodeficiency Virus Replication by a Dual CCR5/CXCR4 Antagonist
Published in Journal of Virology (01-12-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity
Published in Virology (New York, N.Y.) (05-07-2007)“…Abstract The chemokine receptor CXCR4 functions as one of the HIV-1 coreceptors and can be considered as an attractive target for the development of novel…”
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Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100
Published in Molecular pharmacology (01-07-2001)“…The bicyclam AMD3100 is a highly potent and selective CXCR4 antagonist with strong antiviral activity against human immunodeficiency virus (HIV)-1 and HIV-2,…”
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Potential occupational health problems for dentists in Flanders, Belgium
Published in Clinical oral investigations (01-03-2006)“…The aim of this study was to gather data on occupational health effects among Flemish dentists. A questionnaire on various potential health effects was sent…”
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Evaluation of SDF‐1/CXCR4‐induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry
Published in Cytometry. Part A (01-01-2003)“…Background The chemokine receptors CXCR4 and CCR5 are the main coreceptors for human immunodeficiency virus (HIV) 1 to enter its target cells. The antiviral…”
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Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry
Published in FEBS letters (10-07-2003)“…The interaction of the CXCR4 antagonist AMD3100 with its target is greatly influenced by specific aspartate residues in the receptor protein, including Asp 171…”
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CADA Inhibits Human Immunodeficiency Virus and Human Herpesvirus 7 Replication by Down-modulation of the Cellular CD4 Receptor
Published in Virology (New York, N.Y.) (25-10-2002)“…The novel antiviral agent cyclotriazadisulfonamide (CADA) inhibited human immunodeficiency virus (HIV) (IC 50, 0.3–3.2 μM) and human herpesvirus 7 (HHV-7)…”
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The antiviral activity of the CXCR4 antagonist AMD3100 is independent of the cytokine-induced CXCR4/HIV coreceptor expression level
Published in AIDS research and human retroviruses (01-12-2003)“…The chemokine receptor CXCR4 is the main coreceptor used by T-tropic X4 HIV-1 strains to infect its target T cells. It has been proven that the CXCR4…”
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Molecular cloning and expression of a chicken pituitary adenylate cyclase-activating polypeptide receptor
Published in Brain research. Molecular brain research. (25-08-1999)“…Although, since the isolation of pituitary adenylate cyclase-activating polypeptide (PACAP), a wealth of literature has been published describing its…”
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