Search Results - "Prince, Josh P."
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Functions and Regulation of Meiotic HORMA-Domain Proteins
Published in Genes (27-04-2022)“…During meiosis, homologous chromosomes must recognize, pair, and recombine with one another to ensure the formation of inter-homologue crossover events, which,…”
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Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures
Published in Proceedings of the National Academy of Sciences - PNAS (27-03-2018)“…Inorganic polyphosphate is a ubiquitous, linear biopolymer built of up to thousands of phosphate residues that are linked by energy-rich phosphoanhydride…”
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Acyl carrier protein promotes MukBEF action in Escherichia coli chromosome organization-segregation
Published in Nature communications (18-11-2021)“…Structural Maintenance of Chromosomes (SMC) complexes act ubiquitously to compact DNA linearly, thereby facilitating chromosome organization-segregation. SMC…”
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The kleisin subunit controls the function of C. elegans meiotic cohesins by determining the mode of DNA binding and differential regulation by SCC-2 and WAPL-1
Published in eLife (31-08-2023)“…The cohesin complex plays essential roles in chromosome segregation, 3D genome organisation, and DNA damage repair through its ability to modify DNA topology…”
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5
Competitive binding of MatP and topoisomerase IV to the MukB hinge domain
Published in eLife (29-09-2021)“…Structural Maintenance of Chromosomes (SMC) complexes have ubiquitous roles in compacting DNA linearly, thereby promoting chromosome organization-segregation…”
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