Search Results - "Primdahl, Karoline G"
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Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2 n-3 DPA
Published in Chemistry : a European journal (01-02-2022)“…Herein we report the first total synthesis of RvD2 , an endogenously formed mediator biosynthesized from the omega-3 fatty acid n-3 docosapentaenoic acid. The…”
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Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2n‐3 DPA
Published in Chemistry : a European journal (01-02-2022)“…Herein we report the first total synthesis of RvD2n‐3 DPA, an endogenously formed mediator biosynthesized from the omega‐3 fatty acid n‐3 docosapentaenoic…”
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A pyridinium anionic ring-opening reaction applied to the stereodivergent syntheses of Piperaceae natural products
Published in Organic & biomolecular chemistry (28-11-2020)“…A stereodivergent strategy has been devised to access the diene motif found in biologically active compounds from the Piperaceae family. Herein the first total…”
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Synthesis, molecular modelling studies and biological evaluation of new oxoeicosanoid receptor 1 agonists
Published in Bioorganic & medicinal chemistry (23-07-2018)“…[Display omitted] The oxoeicosanoid receptor 1 (OXER1) is a member of the G-protein coupled receptors (GPCR) family, and is involved in inflammatory processes…”
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Synthesis of 13(R)‑Hydroxy‑7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R‑HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins
Published in Journal of natural products (Washington, D.C.) (28-10-2016)“…Specialized pro-resolving lipid mediators are biosynthesized during the resolution phase of acute inflammation from n-3 polyunsaturated fatty acids. Recently,…”
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PD n-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function
Published in Cell chemical biology (21-06-2018)“…Macrophages are central in orchestrating the clearance of apoptotic cells and cellular debris during inflammation, with the mechanism(s) regulating this…”
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