Search Results - "Prill, Kendal"

Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases by Prill, Kendal, Dawson, John F

“…Sarcomere assembly and maintenance are essential physiological processes required for cardiac and skeletal muscle function and organism mobility. Over decades…”
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Chaperones and the Proteasome System: Regulating the Construction and Demolition of Striated Muscle by Carlisle, Casey, Prill, Kendal, Pilgrim, Dave

“…Protein folding factors (chaperones) are required for many diverse cellular functions. In striated muscle, chaperones are required for contractile protein…”
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Myomesin is part of an integrity pathway that responds to sarcomere damage and disease by Prill, Kendal, Carlisle, Casey, Stannard, Megan, Windsor Reid, Pamela J, Pilgrim, David B

“…The structure and function of the sarcomere of striated muscle is well studied but the steps of sarcomere assembly and maintenance remain under-characterized…”
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Homology-Directed Repair in Zebrafish: Witchcraft and Wizardry? by Prill, Kendal, Dawson, John F

“…Introducing desired mutations into the genome of model organisms is a priority for all research focusing on protein function and disease modeling. The need to…”
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Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly by Prill, Kendal, Windsor Reid, Pamela, Wohlgemuth, Serene L, Pilgrim, David B

“…The vertebrate sarcomere is a complex and highly organized contractile structure whose assembly and function requires the coordination of hundreds of proteins…”
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The titin A-band rod domain is dispensable for initial thick filament assembly in zebrafish by Myhre, J. Layne, Hills, Jordan A., Prill, Kendal, Wohlgemuth, Serene L., Pilgrim, David B.

“…The sarcomeres of skeletal and cardiac muscle are highly structured protein arrays, consisting of thick and thin filaments aligned precisely to one another and…”
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Correction: Still Heart Encodes a Structural HMT, SMYD1b, with Chaperone-Like Function during Fast Muscle Sarcomere Assembly by Prill, Kendal, Reid, Pamela Windsor, Wohlgemuth, Serene L, Pilgrim, David B

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Myosin Quality Control Systems in Zebrafish Skeletal Muscle Development by Carlisle, Casey, Prill, Kendal, Pilgrim, David

“…In order to maintain homeostasis, defective proteins must be identified, removed, and replaced. In skeletal muscle, failures in this process can lead to a…”
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Increasing the calcium sensitivity of muscle using trifluoperazine-induced manipulations in silico, in vitro and in vivo systems by Prill, Kendal, Jones, Michael R., Steffensen, Karl, Teng, Grace Zi, Dawson, John F.

“…Many therapeutics for cardiomyopathy treat the symptoms of the disease rather than the underlying mechanism. The mechanism of cardiomyopathy onset is believed…”
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