Search Results - "Prigge, Elena‐Sophie"

Diagnostic accuracy of p16INK4a immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta‐analysis by Prigge, Elena‐Sophie, Arbyn, Marc, von Knebel Doeberitz, Magnus, Reuschenbach, Miriam

“…The accurate diagnosis of human papillomavirus (HPV) causality in oropharyngeal squamous cell carcinomas (OPSCC) is likely to influence therapeutic decisions…”
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Prognostic Impact of AJCC/UICC 8th Edition New Staging Rules in Oropharyngeal Squamous Cell Carcinoma by Würdemann, Nora, Wagner, Steffen, Sharma, Shachi Jenny, Prigge, Elena-Sophie, Reuschenbach, Miriam, Gattenlöhner, Stefan, Klussmann, Jens Peter, Wittekindt, Claus

“…The purpose of this study was to test whether the 8th edition of the AJCC/UICC TNM staging system (UICC) precisely differentiates between stages and reflects…”
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CD56‐positive lymphocyte infiltration in relation to human papillomavirus association and prognostic significance in oropharyngeal squamous cell carcinoma by Wagner, Steffen, Wittekindt, Claus, Reuschenbach, Miriam, Hennig, Ben, Thevarajah, Mauran, Würdemann, Nora, Prigge, Elena‐Sophie, von Knebel Doeberitz, Magnus, Dreyer, Thomas, Gattenlöhner, Stefan, Peter Klussmann, Jens

“…Human papillomavirus (HPV)‐related squamous cell carcinoma of the oropharynx (OSCC) are clinical and biological distinct from their HPV‐unrelated counterparts…”
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PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis by Ganzleben, Ingo, He, Gui-Wei, Günther, Claudia, Prigge, Elena-Sophie, Richter, Karsten, Rieker, Ralf J., Mougiakakos, Dimitrios, Neurath, Markus F., Becker, Christoph

“…Rationale Mitochondrial homeostasis has recently emerged as a focal point in the pathophysiology of idiopathic pulmonary fibrosis (IPF), but conflicting data…”
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Targeted deep sequencing of mucinous ovarian tumors reveals multiple overlapping RAS-pathway activating mutations in borderline and cancerous neoplasms by Mackenzie, Robertson, Kommoss, Stefan, Winterhoff, Boris J, Kipp, Benjamin R, Garcia, Joaquin J, Voss, Jesse, Halling, Kevin, Karnezis, Anthony, Senz, Janine, Yang, Winnie, Prigge, Elena-Sophie, Reuschenbach, Miriam, Doeberitz, Magnus Von Knebel, Gilks, Blake C, Huntsman, David G, Bakkum-Gamez, Jamie, McAlpine, Jessica N, Anglesio, Michael S

“…Mucinous ovarian tumors represent a distinct histotype of epithelial ovarian cancer. The rarest (2-4 % of ovarian carcinomas) of the five major histotypes,…”
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Prognostic Relevance of HPV Infection and p16 Overexpression in Squamous Cell Anal Cancer by Mai, Sabine, MD, Welzel, Grit, MSc, Ottstadt, Martine, MD, Lohr, Frank, MD, Severa, Sebastin, Prigge, Elena-Sophie, MD, Wentzensen, Nicolas, MD, Trunk, Marcus J., MD, Wenz, Frederik, MD, von Knebel-Doeberitz, Magnus, MD, Reuschenbach, Miriam, MD

“…Purpose Human papillomavirus (HPV) DNA and p16 status have both been reported as prognostic factors in anal cancer, but the prognostic relevance of combined…”
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Methylation status of HPV16 E2‐binding sites classifies subtypes of HPV‐associated oropharyngeal cancers by Reuschenbach, Miriam, Huebbers, Christian U., Prigge, Elena‐Sophie, Bermejo, Justo Lorenzo, Kalteis, Martin S., Preuss, Simon F., Seuthe, Inga M.C., Kolligs, Jutta, Speel, Ernst‐Jan M., Olthof, Nadine, Kremer, Bernd, Wagner, Steffen, Klussmann, Jens P., Vinokurova, Svetlana, von Knebel Doeberitz, Magnus

“…BACKGROUND The human papillomavirus (HPV) E2 protein is a transcriptional repressor of the oncogenes E6/E7 and loss of E2 function is considered a key step in…”
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Organotypic Co-Cultures as a Novel 3D Model for Head and Neck Squamous Cell Carcinoma by Engelmann, Luca, Thierauf, Julia, Koerich Laureano, Natalia, Stark, Hans-Juergen, Prigge, Elena-Sophie, Horn, Dominik, Freier, Kolja, Grabe, Niels, Rong, Chao, Federspil, Philippe, Zaoui, Karim, Plinkert, Peter K., Rotter, Nicole, von Knebel Doeberitz, Magnus, Hess, Jochen, Affolter, Annette

“…Background: Head and neck squamous cell carcinomas (HNSCC) are phenotypically and molecularly heterogeneous and frequently develop therapy resistance. Reliable…”
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Predictors for Survival of Patients with Squamous Cell Carcinoma of Unknown Primary in the Head and Neck Region by Wagner, Steffen, Langer, Christine, Wuerdemann, Nora, Reiser, Susanne, Abing, Helen, Pons-Kühnemann, Jörn, Prigge, Elena-Sophie, von Knebel Doeberitz, Magnus, Gattenlöhner, Stefan, Waterboer, Tim, Schroeder, Lea, Arens, Christoph, Klussmann, Jens Peter, Wittekindt, Claus

“…Human papillomavirus (HPV) status is the most important predictor of survival in oropharyngeal squamous cell carcinoma (OPSCC). In patients with cervical lymph…”
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Treatment resistance analysis reveals GLUT‐1‐mediated glucose uptake as a major target of synthetic rocaglates in cancer cells by Sieber‐Frank, Julia, Stark, Hans‐Jürgen, Kalteis, Simon, Prigge, Elena‐Sophie, Köhler, Richard, Andresen, Carolin, Henkel, Thomas, Casari, Georg, Schubert, Tobias, Fischl, Wolfgang, Li‐Weber, Min, Krammer, Peter H., Knebel Doeberitz, Magnus, Kopitz, Jürgen, Kloor, Matthias, Ahadova, Aysel

“…Rocaglates are natural compounds that have been extensively studied for their ability to inhibit translation initiation. Rocaglates represent promising drug…”
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Deep Learning Predicts HPV Association in Oropharyngeal Squamous Cell Carcinomas and Identifies Patients with a Favorable Prognosis Using Regular H&E Stains by Klein, Sebastian, Quaas, Alexander, Quantius, Jennifer, Löser, Heike, Meinel, Jörn, Peifer, Martin, Wagner, Steffen, Gattenlöhner, Stefan, Wittekindt, Claus, von Knebel Doeberitz, Magnus, Prigge, Elena-Sophie, Langer, Christine, Noh, Ka-Won, Maltseva, Margaret, Reinhardt, Hans Christian, Büttner, Reinhard, Klussmann, Jens Peter, Wuerdemann, Nora

“…Human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma (OPSCC) is tumorigenic and has been associated with a favorable prognosis compared with…”
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Increasing Incidence rates of Oropharyngeal Squamous Cell Carcinoma in Germany and Significance of Disease Burden Attributed to Human Papillomavirus by Wittekindt, Claus, Wagner, Steffen, Bushnak, Ayman, Prigge, Elena-Sophie, von Knebel Doeberitz, Magnus, Würdemann, Nora, Bernhardt, Katharina, Pons-Kühnemann, Jörn, Maulbecker-Armstrong, Catharina, Klussmann, Jens Peter

“…Increasing incidences of head and neck cancers and rising proportions of these associated with human papillomavirus (HPV), especially in the oropharynx, have…”
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Human papillomavirus association is the most important predictor for surgically treated patients with oropharyngeal cancer by Wagner, Steffen, Wittekindt, Claus, Sharma, Shachi Jenny, Wuerdemann, Nora, Jüttner, Theresa, Reuschenbach, Miriam, Prigge, Elena-Sophie, von Knebel Doeberitz, Magnus, Gattenlöhner, Stefan, Burkhardt, Ernst, Pons-Kühnemann, Jörn, Klussmann, Jens Peter

“…Background: Upfront surgery is a valuable treatment option for oropharyngeal squamous cell carcinoma (OPSCC) and risk stratification is emerging for treatment…”
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Prognostic Significance of HPV DNA and p16INK4a in Anal Cancer: A Systematic Review and Meta-Analysis by Urbute, Aivara, Rasmussen, Christina Louise, Belmonte, Federica, Obermueller, Theresa, Prigge, Elena-Sophie, Arbyn, Marc, Verdoodt, Freija, Kjaer, Susanne K.

“…Abstract We conducted a systematic review and meta-analysis of observational studies evaluating survival in patients with anal cancer, according to human…”
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Role of DNA methylation in HPV associated lesions by von Knebel Doeberitz, Magnus, Prigge, Elena-Sophie

“…Papillomavirus replication is tightly linked to squamous epithelial differentiation which in turn is governed to a large extent by epigenetic remodeling of…”
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p16(INK4a) /Ki-67 co-expression specifically identifies transformed cells in the head and neck region by Prigge, Elena-Sophie, Toth, Csaba, Dyckhoff, Gerhard, Wagner, Steffen, Müller, Franziska, Wittekindt, Claus, Freier, Kolja, Plinkert, Peter, Hoffmann, Jürgen, Vinokurova, Svetlana, Klussmann, Jens Peter, von Knebel Doeberitz, Magnus, Reuschenbach, Miriam

“…p16(INK4a) immunohistochemical overexpression is an overall reliable surrogate marker of human papillomavirus (HPV)-associated head and neck squamous cell…”
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Diagnostic accuracy of p16 INK4a immunohistochemistry in oropharyngeal squamous cell carcinomas: A systematic review and meta-analysis by Prigge, Elena-Sophie, Arbyn, Marc, von Knebel Doeberitz, Magnus, Reuschenbach, Miriam

“…The accurate diagnosis of human papillomavirus (HPV) causality in oropharyngeal squamous cell carcinomas (OPSCC) is likely to influence therapeutic decisions…”
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A phase 1/2a study to test the safety and immunogenicity of a p16(INK4a) peptide vaccine in patients with advanced human papillomavirus-associated cancers by Reuschenbach, Miriam, Pauligk, Claudia, Karbach, Julia, Rafiyan, Mohammad-Reza, Kloor, Matthias, Prigge, Elena-Sophie, Sauer, Madeleine, Al-Batran, Salah-Eddin, Kaufmann, Andreas M, Schneider, Achim, Jäger, Elke, von Knebel Doeberitz, Magnus

“…The cyclin-dependent kinase inhibitor p16(INK4a) is strongly and consistently overexpressed in all human papillomavirus (HPV)-associated cancers. Therefore,…”
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5-aza-2'-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells by Stich, Maximilian, Ganss, Lennard, Puschhof, Jens, Prigge, Elena-Sophie, Reuschenbach, Miriam, Guiterrez, Ana, Vinokurova, Svetlana, von Knebel Doeberitz, Magnus

“…High-risk human papillomaviruses (hr HPVs) may cause various human cancers and associated premalignant lesions. Transformation of the host cells is triggered…”
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Influence of human papillomavirus and p16(INK4a) on treatment outcome of patients with anal cancer by Koerber, Stefan Alexander, Schoneweg, Clara, Slynko, Alla, Krug, David, Haefner, Matthias F, Herfarth, Klaus, Debus, Juergen, Sterzing, Florian, von Knebel Doeberitz, Magnus, Prigge, Elena-Sophie, Reuschenbach, Miriam

“…The purpose of this study was to evaluate HPV-DNA and p16(INK4a) (p16) expression as prognostic markers for outcome in patients with anal cancer. From January…”
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