Search Results - "Prifti, Edi"
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Major microbiota dysbiosis in severe obesity: fate after bariatric surgery
Published in Gut (01-01-2019)“…Decreased gut microbial gene richness (MGR) and compositional changes are associated with adverse metabolism in overweight or moderate obesity, but lack…”
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Human gut microbes impact host serum metabolome and insulin sensitivity
Published in Nature (London) (21-07-2016)“…Increased potential for branched-chain amino acid and lipopolysaccharide biosynthesis in the gut microbiome of insulin-resistant individuals suggests that…”
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Alterations of the human gut microbiome in liver cirrhosis
Published in Nature (London) (04-09-2014)“…Liver cirrhosis occurs as a consequence of many chronic liver diseases that are prevalent worldwide. Here we characterize the gut microbiome in liver cirrhosis…”
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Dietary intervention impact on gut microbial gene richness
Published in Nature (London) (29-08-2013)“…In obese and overweight individuals, diet-induced weight loss and weight-stabilization interventions improve the low microbiota gene richness and clinical…”
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5
From correlation to causality: the case of Subdoligranulum
Published in Gut microbes (09-11-2020)“…Gut microbes are considered as major factors contributing to human health. Nowadays, the vast majority of the data available in the literature are mostly…”
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Protein supplementation during an energy-restricted diet induces visceral fat loss and gut microbiota amino acid metabolism activation: a randomized trial
Published in Scientific reports (02-08-2021)“…Interactions between diet and gut microbiota are critical regulators of energy metabolism. The effects of fibre intake have been deeply studied but little is…”
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Functional alterations and predictive capacity of gut microbiome in type 2 diabetes
Published in Scientific reports (16-12-2023)“…The gut microbiome plays a significant role in the development of Type 2 Diabetes Mellitus (T2DM), but the functional mechanisms behind this association merit…”
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Effect of congenital adrenal hyperplasia treated by glucocorticoids on plasma metabolome: a machine-learning-based analysis
Published in Scientific reports (01-06-2020)“…Background. Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency leads to impaired cortisol biosynthesis. Treatment includes glucocorticoid…”
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Gut Microbiota Profile of Obese Diabetic Women Submitted to Roux-en-Y Gastric Bypass and Its Association with Food Intake and Postoperative Diabetes Remission
Published in Nutrients (21-01-2020)“…Gut microbiota composition is influenced by environmental factors and has been shown to impact body metabolism. To assess the gut microbiota profile before and…”
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Major depletion of insulin sensitivity-associated taxa in the gut microbiome of persons living with HIV controlled by antiretroviral drugs
Published in BMC medical genomics (13-08-2024)“…Persons living with HIV (PWH) harbor an altered gut microbiome (higher abundance of Prevotella and lower abundance of Bacillota and Ruminococcus lineages)…”
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FunNet: an integrative tool for exploring transcriptional interactions
Published in Bioinformatics (15-11-2008)“…We describe here an exploratory tool, called FunNet, which implements an original systems biology approach, aiming to improve the biological relevance of the…”
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Gut microbiota changes after metabolic surgery in adult diabetic patients with mild obesity: a randomised controlled trial
Published in Diabetology and metabolic syndrome (21-05-2021)“…Abstract Background Roux-en-Y gastric bypass (RYGB) surgery is one of the most efficient procedures for the treatment of obesity, also improving metabolic and…”
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Differential effects of macronutrient content in 2 energy-restricted diets on cardiovascular risk factors and adipose tissue cell size in moderately obese individuals: a randomized controlled trial
Published in The American journal of clinical nutrition (01-01-2012)“…Background: The most effective and safe dietary approach for weight loss and its impact on the metabolic functions and morphology of adipose tissue remain…”
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Effect of genome and environment on metabolic and inflammatory profiles
Published in PloS one (08-04-2015)“…Twin and family studies have established the contribution of genetic factors to variation in metabolic, hematologic and immunological parameters. The majority…”
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Association of N-Acetyl Asparagine with QTc in Diabetes: A Metabolomics Study
Published in Biomedicines (01-08-2022)“…Changes in the cardio-metabolomics profile and hormonal status have been associated with long QT syndrome, sudden cardiac death and increased mortality. The…”
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Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
Published in Gut (01-03-2016)“…Individuals with obesity and type 2 diabetes differ from lean and healthy individuals in their abundance of certain gut microbial species and microbial gene…”
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Abstract 16962: A Polygenic Predictor of Baseline QT is Associated With Sotalol-Induced QT Prolongation
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Background: Drug-induced QT interval prolongation raises the risk of fatal arrhythmia and is a central issue in safety pharmacology. Yet…”
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18
An integrated catalog of reference genes in the human gut microbiome
Published in Nature biotechnology (01-08-2014)“…Li et al. provide the largest catalog of genes in the human gut microbiome based on samples from >1,200 individuals across three continents. Many analyses of…”
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Microbiome and metabolome features of the cardiometabolic disease spectrum
Published in Nature Medicine (01-02-2022)“…Previous microbiome and metabolome analyses exploring non-communicable diseases have paid scant attention to major confounders of study outcomes, such as…”
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Richness of human gut microbiome correlates with metabolic markers
Published in Nature (London) (29-08-2013)“…We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we report the human gut microbial composition in a population sample of…”
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