Search Results - "Priestley, Richard"

Antimalarial activity of primaquine operates via a two-step biochemical relay by Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard S., Saif, Ahmed, March, Sandra, Wong, Michael H. L., Leung, Suet, Miller, Alex B., Baker, David A., Alano, Pietro, Paine, Mark J. I., Bhatia, Sangeeta N., O’Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A.

“…Primaquine (PQ) is an essential antimalarial drug but despite being developed over 70 years ago, its mode of action is unclear. Here, we demonstrate that…”
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Consumption Fluctuations and Expected Returns by ATANASOV, VICTORIA, MØLLER, STIG V., PRIESTLEY, RICHARD

“…This paper introduces a novel consumption-based variable, cyclical consumption, and examines its predictive properties for stock returns. Future expected stock…”
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Functional Selectivity at Cannabinoid Receptors by Priestley, Richard, Glass, Michelle, Kendall, David

“…It is now clear that, in contrast to traditional descriptions of G protein-coupled receptor signaling, agonists can activate or inhibit characteristic patterns…”
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Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis by Turner, Joseph D., Sharma, Raman, Al Jayoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Priestley, Richard S., Murphy, Emma A., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., McCall, John, Ford, Louise, Hemingway, Janet, Ward, Stephen A., Taylor, Mark J.

“…Elimination of filariasis requires a macrofilaricide treatment that can be delivered within a 7-day period. Here we have identified a synergy between the…”
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A potential role for cannabinoid receptors in the therapeutic action of fenofibrate by Priestley, Richard S., Nickolls, Sarah A., Alexander, Stephen P. H., Kendall, David A.

“…Cannabinoids are reported to have actions through peroxisome proliferator‐activated receptors (PPARs), which led us to investigate PPAR agonists for activity…”
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A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6 by Priestley, Richard S., Cheung, Jonathan, Murphy, Emma J., Ehebauer, Matthias T., Davis, John B., Di Daniel, Elena

“…Dickkopf-related protein 1 (Dkk1) is a secreted protein ligand of low-density lipoprotein receptor-related protein 6 (LRP6), which antagonises canonical Wnt…”
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Potent Antimalarial 2‑Pyrazolyl Quinolone bc 1 (Qi) Inhibitors with Improved Drug-like Properties by David Hong, W, Leung, Suet C, Amporndanai, Kangsa, Davies, Jill, Priestley, Richard S, Nixon, Gemma L, Berry, Neil G, Samar Hasnain, S, Antonyuk, Svetlana, Ward, Stephen A, Biagini, Giancarlo A, O’Neill, Paul M

“…A series of 2-pyrazolyl quinolones has been designed and synthesized in 5–7 steps to optimize for both in vitro antimalarial potency and various in vitro drug…”
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Time-Varying Risk Premiums and the Output Gap by Cooper, Ilan, Priestley, Richard

“…The output gap, a production-based macroeconomic variable, is a strong predictor of U. S. stock returns. It is a prime business cycle indicator that does not…”
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Expected returns, risk and the integration of international bond markets by Barr, David G., Priestley, Richard

“…In this paper we model expected risks and returns on government bonds, allowing for partial integration of national and world bond markets. Using a conditional…”
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The expected returns and valuations of private and public firms by Cooper, Ilan, Priestley, Richard

“…Characteristics play a similar role in describing returns in private firms as in public firms. This evidence suggests a causal effect of optimal investment…”
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Real investment and risk dynamics by Cooper, Ilan, Priestley, Richard

“…We ask to what extent the negative relation between investment and average stock returns is driven by risk. We show that: (i) the average return spread between…”
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Dividend Growth, Cash Flow, and Discount Rate News by Garrett, Ian, Priestley, Richard

“…Using a new variable based on a model of dividend smoothing, we find that dividend growth is highly predictable and that cash flow news contributes importantly…”
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The World Business Cycle and Expected Returns by Cooper, Ilan, Priestley, Richard

“…We study the predictability of stock returns using a pure macroeconomic measure of the world business cycle, namely the world's capital to output ratio. This…”
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The effects of stock index futures trading on stock index volatility: An analysis of the asymmetric response of volatility to news by Antoniou, Antonios, Holmes, Phil, Priestley, Richard

“…A study examines the impact of futures trading on stock market volatility. In doing so, it extends the traditional analysis of examining whether futures…”
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Dividend Smoothing and Predictability by Chen, Long, Da, Zhi, Priestley, Richard

“…The relative predictability of returns and dividends is a central issue because it forms the paradigm to interpret asset price variation. A little studied…”
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Dynamics of photoexcited states and charge carriers in organic thin films: Alq3 by Walser, Ardie D., Sokolik, Igor, Priestley, Richard, Dorsinville, Roger

“…We demonstrate a method for observing and analyzing the dynamics of photoexcited molecular states and charge carriers in organic thin films, by measuring…”
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Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease: Nonhuman/Target identification and validation studies: Inflammation and innate immunity by Obst, Juliane, Bradshaw, William, Roberts, Hazel Hall, Priestley, Richard, Jimenez‐Antunez, Carmen, Cowley, Sally A., Gileadi, Opher, Mead, Emma, Daniel, Elena Di, Davis, John B.

“…Abstract Background Genome wide association studies (GWAS) and systems biology approaches have identified several Alzheimer’s disease (AD) risk associated…”
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Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease by Obst, Juliane, Bradshaw, William, Roberts, Hazel Hall, Priestley, Richard, Jimenez‐Antunez, Carmen, Cowley, Sally A., Gileadi, Opher, Mead, Emma, Daniel, Elena Di, Davis, John B.

“…Background Genome wide association studies (GWAS) and systems biology approaches have identified several Alzheimer’s disease (AD) risk associated genes…”
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Labor Income, Relative Wealth Concerns, and the Cross Section of Stock Returns by Gómez, Juan-Pedro, Priestley, Richard, Zapatero, Fernando

“…The finance literature documents a relation between labor income and the cross section of stock returns. One possible explanation for this is the hedging…”
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29‐4: Edge Strength Measurement of Free‐form Displays by Jang, Bosun, Priestley, Richard, Liu, Dani, Ono, Toshihiko, Segar, Michael, Sundaram, Bala

“…The Edge Strength Measurement System (ESMS) is proposed as method for measuring the edge strength of free‐form displays. Its feasibility on free‐form…”
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