Search Results - "Priestley, Anne"

Ku80: Product of the XRCC5 Gene and Its Role in DNA Repair and V(D)J Recombination by Taccioli, Guillermo E., Gottlieb, Tanya M., Blunt, Tracy, Priestley, Anne, Demengeot, Jocelyne, Mizuta, Ryushin, Lehmann, Alan R., Alt, Frederick W., Jackson, Stephen P., Jeggo, Penny A.

“…The radiosensitive mutant xrs-6, derived from Chinese hamster ovary cells, is defective in DNA double-strand break repair and in ability to undergo V(D)J…”
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DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage by Wahl, Geoffrey M, Jimenez, Gretchen S, Bryntesson, Fredrik, Torres-Arzayus, Maria I, Priestley, Anne, Beeche, Michelle, Saito, Shin'ichi, Sakaguchi, Kazuyasu, Appella, Ettore, Jeggo, Penny A, Taccioli, Guillermo E, Hubank, Michael

“…Damage to DNA in the cell activates the tumour-suppressor protein p53 (ref. 1), and failure of this activation leads to genetic instability and a…”
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Combined immunodeficiency associated with increased apoptosis of lymphocytes and radiosensitivity of fibroblasts by PEAKE, J, WAUGH, A, MALAISE, E. P, FISCHER, A, HIVROZ, C, JEGGO, P. A, LE DEIST, F, PRIESTLEY, A, RIEUX-LAUCAT, F, FORAY, N, CAPULAS, E, SINGLETON, B. K, DE VILLARTAY, J.-P, CANT, A

“…Severe immunodeficiency characterized by lymphopenia was found in two siblings, one of whom was examined in detail. The calcium flux, pattern of tyrosine…”
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Comparative human cellular radiosensitivity: I. The effect of SV40 transformation and immortalisation on the gamma-irradiation survival of skin derived fibroblasts from normal individuals and from ataxia-telangiectasia patients and heterozygotes by Arlett, C F, Green, M H, Priestley, A, Harcourt, S A, Mayne, L V

“…We have compared cell killing following 60Co gamma irradiation in 22 primary human fibroblast strains, nine SV40-immortalized human fibroblast lines and seven…”
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Comparative human cellular radiosensitivity: II. The survival following gamma-irradiation of unstimulated (G0) T-lymphocytes, T-lymphocyte lines, lymphoblastoid cell lines and fibroblasts from normal donors, from ataxia-telangiectasia patients and from ataxia-telangiectasia heterozygotes by Cole, J, Arlett, C F, Green, M H, Harcourt, S A, Priestley, A, Henderson, L, Cole, H, James, S E, Richmond, F

“…We have measured clonal survival following gamma-irradiation of unstimulated (G0) T-lymphocytes from 35 donors, of 11 T-lymphocyte cell lines, of six…”
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Ku80: product of the XRCC5 gene and its role in DNA repair and VJ recombination by Tacciolo, Guillermo E, Gottlieb, Tanya M, Blunt, Tracy, Priestley, Anne, Mizuta, Ryushin, Lehmann, Alan R, Alt, Frederick W, Jackson, Stephen P, Jeggo, Penny A, Demengeot, Jocelyne

“…The radiosensitive mutant xrs-6, derived from Chinese hamster ovary cells, is defective in DNA double-strand break repair and in ability to undergo V(D)J…”
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Efficient immortalization and morphological transformation of human fibroblasts by transfection with SV40 DNA linked to a dominant marker by Mayne, L V, Priestley, A, James, M R, Burke, J F

“…Immortal cell lines are essential for genetic and biochemical studies. Unlike rodent cells, which will form continuously growing cultures either spontaneously…”
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A YAC Contig Encompassing the XRCC5 (Ku80) DNA Repair Gene and Complementation of Defective Cells by YAC Protoplast Fusion by Blunt, Tracy, Taccioli, Guillermo E., Priestley, Anne, Hafezparast, Majid, McMillan, Trevor, Liu, Jing, Cole, Charlotte C., White, Jacqueline, Alt, Frederick W., Jackson, Stephen P., Schurr, Erwin, Lehmann, Alan R., Jeggo, Penny A.

“…The Chinese hamster ovaryxrsmutants are sensitive to ionizing radiation, defective in DNA double-strand break rejoining, and unable to carry out V(D)J…”
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Coregulation of the human O6-methylguanine-DNA methyltransferase with two unrelated genes that are closely linked by KARRAN, P, STEPHENSON, C, MACPHERSON, P, CAIRNS-SMITH, S, PRIESTLEY, A

“…The loss of expression of the enzyme O6-methylguanine-DNA methyltransferase (the Mex- phenotype), which often results from cellular transformation, confers…”
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The preparation of 11-cis-retinal by Knowles, A, Priestley, A

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Double strand break rejoining by the Ku-dependent mechanism of non-homologous end-joining by Jeggo, P, Singleton, B, Beamish, H, Priestley, A

“…The DNA-dependent protein kinase functions in the repair of DNA double strand breaks (DSBs) and in V(D)J recombination. To gain insight into the function of…”
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