Search Results - "Priebe, Lutz"

The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia by Håvik, Bjarte, Le Hellard, Stephanie, Rietschel, Marcella, Lybæk, Helle, Djurovic, Srdjan, Mattheisen, Manuel, Mühleisen, Thomas W, Degenhardt, Franziska, Priebe, Lutz, Maier, Wolfgang, Breuer, Rene, Schulze, Thomas G, Agartz, Ingrid, Melle, Ingrid, Hansen, Thomas, Bramham, Clive R, Nöthen, Markus M, Stevens, Beth, Werge, Thomas, Andreassen, Ole A, Cichon, Sven, Steen, Vidar M

“…Background Patients with schizophrenia often suffer from cognitive dysfunction, including impaired learning and memory. We recently demonstrated that long-term…”
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Common and rare variant analysis in early-onset bipolar disorder vulnerability by Jamain, Stéphane, Cichon, Sven, Etain, Bruno, Mühleisen, Thomas W, Georgi, Alexander, Zidane, Nora, Chevallier, Lucie, Deshommes, Jasmine, Nicolas, Aude, Henrion, Annabelle, Degenhardt, Franziska, Mattheisen, Manuel, Priebe, Lutz, Mathieu, Flavie, Kahn, Jean-Pierre, Henry, Chantal, Boland, Anne, Zelenika, Diana, Gut, Ivo, Heath, Simon, Lathrop, Mark, Maier, Wolfgang, Albus, Margot, Rietschel, Marcella, Schulze, Thomas G, McMahon, Francis J, Kelsoe, John R, Hamshere, Marian, Craddock, Nicholas, Nöthen, Markus M, Bellivier, Frank, Leboyer, Marion

“…Bipolar disorder is one of the most common and devastating psychiatric disorders whose mechanisms remain largely unknown. Despite a strong genetic contribution…”
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Levetiracetam resistance: Synaptic signatures & corresponding promoter SNPs in epileptic hippocampi by Grimminger, Tanja, Pernhorst, Katharina, Surges, Rainer, Niehusmann, Pitt, Priebe, Lutz, von Lehe, Marec, Hoffmann, Per, Cichon, Sven, Schoch, Susanne, Becker, Albert J

“…Abstract Pharmacoresistance to antiepileptic drugs (AEDs) is a major clinical problem in patients with mesial temporal lobe epilepsy (mTLE). Levetiracetam…”
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Copy number variants in German patients with schizophrenia by Priebe, Lutz, Degenhardt, Franziska, Strohmaier, Jana, Breuer, René, Herms, Stefan, Witt, Stephanie H, Hoffmann, Per, Kulbida, Rebecca, Mattheisen, Manuel, Moebus, Susanne, Meyer-Lindenberg, Andreas, Walter, Henrik, Mössner, Rainald, Nenadic, Igor, Sauer, Heinrich, Rujescu, Dan, Maier, Wolfgang, Rietschel, Marcella, Nöthen, Markus M, Cichon, Sven

“…Large rare copy number variants (CNVs) have been recognized as significant genetic risk factors for the development of schizophrenia (SCZ). However, due to…”
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A Genome-Wide Association Study Suggests Novel Loci Associated with a Schizophrenia-Related Brain-Based Phenotype by Hass, Johanna, Walton, Esther, Kirsten, Holger, Liu, Jingyu, Priebe, Lutz, Wolf, Christiane, Karbalai, Nazanin, Gollub, Randy, White, Tonya, Roessner, Veit, Müller, Kathrin U, Paus, Tomas, Smolka, Michael N, Schumann, Gunter, Scholz, Markus, Cichon, Sven, Calhoun, Vince, Ehrlich, Stefan

“…Patients with schizophrenia and their siblings typically show subtle changes of brain structures, such as a reduction of hippocampal volume. Hippocampal volume…”
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Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample by Degenhardt, Franziska, Priebe, Lutz, Herms, Stefan, Mattheisen, Manuel, Mühleisen, Thomas W., Meier, Sandra, Moebus, Susanne, Strohmaier, Jana, Groß, Magdalena, Breuer, René, Lange, Christoph, Hoffmann, Per, Meyer-Lindenberg, Andreas, Heinz, Andreas, Walter, Henrik, Lucae, Susanne, Wolf, Christiane, Müller-Myhsok, Bertram, Holsboer, Florian, Maier, Wolfgang, Rietschel, Marcella, Nöthen, Markus M., Cichon, Sven

“…The majority of genetic risk factors for major depressive disorder (MDD) still await identification. Since copy number variants (CNVs) have been implicated in…”
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Genome-wide association study reveals two new risk loci for bipolar disorder by Mühleisen, Thomas W., Leber, Markus, Schulze, Thomas G., Strohmaier, Jana, Degenhardt, Franziska, Treutlein, Jens, Mattheisen, Manuel, Forstner, Andreas J., Schumacher, Johannes, Breuer, René, Meier, Sandra, Herms, Stefan, Hoffmann, Per, Lacour, André, Witt, Stephanie H., Reif, Andreas, Müller-Myhsok, Bertram, Lucae, Susanne, Maier, Wolfgang, Schwarz, Markus, Vedder, Helmut, Kammerer-Ciernioch, Jutta, Pfennig, Andrea, Bauer, Michael, Hautzinger, Martin, Moebus, Susanne, Priebe, Lutz, Czerski, Piotr M., Hauser, Joanna, Lissowska, Jolanta, Szeszenia-Dabrowska, Neonila, Brennan, Paul, McKay, James D., Wright, Adam, Mitchell, Philip B., Fullerton, Janice M., Schofield, Peter R., Montgomery, Grant W., Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Krasnow, Valery, Chuchalin, Alexander, Babadjanova, Gulja, Pantelejeva, Galina, Abramova, Lilia I., Tiganov, Alexander S., Polonikov, Alexey, Khusnutdinova, Elza, Alda, Martin, Grof, Paul, Rouleau, Guy A., Turecki, Gustavo, Laprise, Catherine, Rivas, Fabio, Mayoral, Fermin, Kogevinas, Manolis, Grigoroiu-Serbanescu, Maria, Propping, Peter, Becker, Tim, Rietschel, Marcella, Nöthen, Markus M., Cichon, Sven

“…Bipolar disorder (BD) is a common and highly heritable mental illness and genome-wide association studies (GWAS) have robustly identified the first common…”
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Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium by Debette, Stéphanie, Ibrahim Verbaas, Carla A, Bressler, Jan, Bis, Joshua C, Davies, Gail, Wolf, Christiane, Gudnason, Vilmundur, Chibnik, Lori B, deStefano, Anita L, de Quervain, Dominique J.F, Srikanth, Velandai, Lahti, Jari, Grabe, Hans J, Smith, Jennifer A, Priebe, Lutz, Yu, Lei, Karbalai, Nazanin, Hayward, Caroline, Campbell, Harry, Petrovic, Katja, Fornage, Myriam, Chauhan, Ganesh, Yeo, Robin, Boxall, Ruth, Stegle, Oliver, Chouraki, Vincent, Sun, Qi, Resnick, Susan, Oldmeadow, Christopher, Kirin, Mirna, Wright, Alan F, Jonsdottir, Maria K, Au, Rhoda, Becker, Albert, Amin, Najaf, Nalls, Mike A, Turner, Stephen T, Kardia, Sharon L.R, Oostra, Ben, Coker, Laura H, Zhao, Wei, Knopman, David S, Heiss, Gerardo, Gottesman, Rebecca F, Vitart, Veronique, Hastie, Nicholas D, Zgaga, Lina, Rudan, Igor, Polasek, Ozren, Holliday, Elizabeth G, Schofield, Peter, Choi, Seung Hoan, Tanaka, Toshiko, An, Yang, Perry, Rodney T, Sale, Michèle M, Wadley, Virginia G, Liewald, David C, Ridker, Paul M, Gow, Alan J, Pattie, Alison, Porteous, David, Liu, Xuan, Thomson, Russell, Armstrong, Nicola J, Eiriksdottir, Gudny, Assareh, Arezoo A, Kochan, Nicole A, Widen, Elisabeth, Palotie, Aarno, Eriksson, Johan G, van Swieten, John C, Shulman, Joshua M, Beiser, Alexa, Rotter, Jerome, Hoffmann, Wolfgang, Nöthen, Markus M, Ferrucci, Luigi, Attia, John, Uitterlinden, Andre G, Amouyel, Philippe, Amieva, Hélène, Räikkönen, Katri, Hofman, Albert, Longstreth, W.T, DeJager, Philip L, Sachdev, Perminder S, Breteler, Monique M.B, Teumer, Alexander, Cichon, Sven, Chasman, Daniel I, Grodstein, Francine, Papassotiropoulos, Andreas, Bennett, David A, Ikram, M. Arfan, van Duijn, Cornelia M, Launer, Lenore, Fitzpatrick, Annette L, Seshadri, Sudha, Mosley, Thomas H

“…Abstract Background Memory performance in older persons can reflect genetic influences on cognitive function and dementing processes. We aimed to identify…”
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Homozygosity mapping in 64 Syrian consanguineous families with non-specific intellectual disability reveals 11 novel loci and high heterogeneity by RAMI ABOU JAMRA, WOHLFART, Sigrun, HAMDAN, Saber, ISMAEL, Amina, MUHAMMAD, Safia, NÖTHEN, Markus M, SCHUMACHER, Johannes, REIS, André, ZWEIER, Markus, UEBE, Steffen, PRIEBE, Lutz, EKICI, Arif, GIESEBRECHT, Susanne, ABBOUD, Ahmad, MOHAMMED AYMAN AL KHATEEB, FAKHER, Mahmoud

“…Non-specific intellectual disability of autosomal recessive inheritance (NS-ARID) represents an important fraction of severe cognitive dysfunction disorders…”
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DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations by Sharma, Amit, Jamil, Muhammad Ahmer, Nuesgen, Nicole, Schreiner, Felix, Priebe, Lutz, Hoffmann, Per, Herns, Stefan, Nöthen, Markus M, Fröhlich, Holger, Oldenburg, Johannes, Woelfle, Joachim, El-Maarri, Osman

“…Abnormal sex chromosome numbers in humans are observed in Turner (45,X) and Klinefelter (47,XXY) syndromes. Both syndromes are associated with several clinical…”
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Implication of a rare deletion at distal 16p11.2 in schizophrenia by Guha, Saurav, Rees, Elliott, Darvasi, Ariel, Ivanov, Dobril, Ikeda, Masashi, Bergen, Sarah E, Magnusson, Patrik K, Cormican, Paul, Morris, Derek, Gill, Michael, Cichon, Sven, Rosenfeld, Jeffrey A, Lee, Annette, Gregersen, Peter K, Kane, John M, Malhotra, Anil K, Rietschel, Marcella, Nöthen, Markus M, Degenhardt, Franziska, Priebe, Lutz, Breuer, René, Strohmaier, Jana, Ruderfer, Douglas M, Moran, Jennifer L, Chambert, Kimberly D, Sanders, Alan R, Shi, Jianxin, Kendler, Kenneth, Riley, Brien, O'Neill, Tony, Walsh, Dermot, Malhotra, Dheeraj, Corvin, Aiden, Purcell, Shaun, Sklar, Pamela, Iwata, Nakao, Hultman, Christina M, Sullivan, Patrick F, Sebat, Jonathan, McCarthy, Shane, Gejman, Pablo V, Levinson, Douglas F, Owen, Michael J, O'Donovan, Michael C, Lencz, Todd, Kirov, George

“…Large genomic copy number variations have been implicated as strong risk factors for schizophrenia. However, the rarity of these events has created challenges…”
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Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder by Priebe, L, Degenhardt, F A, Herms, S, Haenisch, B, Mattheisen, M, Nieratschker, V, Weingarten, M, Witt, S, Breuer, R, Paul, T, Alblas, M, Moebus, S, Lathrop, M, Leboyer, M, Schreiber, S, Grigoroiu-Serbanescu, M, Maier, W, Propping, P, Rietschel, M, Nöthen, M M, Cichon, S, Mühleisen, T W

“…We used genome-wide single nucleotide polymorphism (SNP) data to search for the presence of copy number variants (CNVs) in 882 patients with bipolar disorder…”
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Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue by Pernhorst, Katharina, van Loo, Karen M.J, von Lehe, Marec, Priebe, Lutz, Cichon, Sven, Herms, Stefan, Hoffmann, Per, Helmstaedter, Christoph, Sander, Thomas, Schoch, Susanne, Becker, Albert J

“…Abstract Many brain disorders, including epilepsy, migraine and depression, manifest with episodic symptoms that may last for various time intervals. Transient…”
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Corrigendum to “Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue” [Brain Res. 1499 (2013) 136–144] by Pernhorst, Katharina, van Loo, Karen M.J, von Lehe, Marec, Priebe, Lutz, Cichon, Sven, Herms, Stefan, Hoffmann, Per, Helmstaedter, Christoph, Sander, Thomas, Schoch, Susanne, Becker, Albert J

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Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia by Forstner, Andreas J., MD, Basmanav, F. Buket, MSc, Mattheisen, Manuel, MD, GROUP Investigators, MSc, Böhmer, Anne C., PhD, Hollegaard, Mads V., BAS, Janson, Esther, MSc, Strengman, Eric, MSc, Priebe, Lutz, MD, Degenhardt, Franziska, PhD, Hoffmann, Per, MSc, Herms, Stefan, MD, Maier, Wolfgang, MD, Mössner, Rainald, MD, Rujescu, Dan, PhD, Ophoff, Roel A., PhD, Moebus, Susanne, MD, DMSc, Mortensen, Preben B., MD, PhD, Børglum, Anders D., MD, DSc, Hougaard, David M., MSc, Frank, Josef, PhD, Witt, Stephanie H., MD, Rietschel, Marcella, PhD, Zimmer, Andreas, MD, Nöthen, Markus M., PhD, Miró, Xavier, PhD, Cichon, Sven

“…Background Schizophrenia is a complex neuropsychiatric disorder of unclear etiology. The strongest known genetic risk factor is the 22q11.2 microdeletion…”
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A common microdeletion affecting a hippocampus- and amygdala-specific isoform of tryptophan hydroxylase 2 is not associated with affective disorders by Hammer, Christian, Degenhardt, Franziska, Priebe, Lutz, Stütz, Adrian M, Heilmann, Stefanie, Waszak, Sebastian M, Schlattl, Andreas, Mangold, Elisabeth, Hoffmann, Per, Nöthen, Markus M, Rietschel, Marcella, Rappold, Gudrun, Korbel, Jan, Cichon, Sven, Niesler, Beate

“…Objectives Copy number variants (CNVs) have been shown to affect susceptibility for neuropsychiatric disorders. To date, studies implicating the serotonergic…”
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Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients by Mühleisen, Thomas W, Basmanav, F. Buket, Forstner, Andreas J, Mattheisen, Manuel, Priebe, Lutz, Herms, Stefan, Breuer, Rene, Moebus, Susanne, Nenadic, Igor, Sauer, Heinrich, Mössner, Rainald, Maier, Wolfgang, Rujescu, Dan, Ludwig, Michael, Rietschel, Marcella, Nöthen, Markus M, Cichon, Sven

“…Abstract Large rare deletions in NRXN1 increase the risk for schizophrenia. The aim of the present study was to determine whether small rare sequence changes…”
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Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder by Cichon, Sven, Mühleisen, Thomas W., Degenhardt, Franziska A., Mattheisen, Manuel, Miró, Xavier, Strohmaier, Jana, Steffens, Michael, Meesters, Christian, Herms, Stefan, Weingarten, Moritz, Priebe, Lutz, Haenisch, Britta, Alexander, Michael, Vollmer, Jennifer, Breuer, René, Schmäl, Christine, Tessmann, Peter, Moebus, Susanne, Wichmann, H.-Erich, Schreiber, Stefan, Müller-Myhsok, Bertram, Lucae, Susanne, Jamain, Stéphane, Leboyer, Marion, Bellivier, Frank, Etain, Bruno, Henry, Chantal, Kahn, Jean-Pierre, Heath, Simon, Hamshere, Marian, O'Donovan, Michael C., Owen, Michael J., Craddock, Nick, Schwarz, Markus, Vedder, Helmut, Kammerer-Ciernioch, Jutta, Reif, Andreas, Sasse, Johanna, Bauer, Michael, Hautzinger, Martin, Wright, Adam, Mitchell, Philip B., Schofield, Peter R., Montgomery, Grant W., Medland, Sarah E., Gordon, Scott D., Martin, Nicholas G., Gustafsson, Omar, Andreassen, Ole, Djurovic, Srdjan, Sigurdsson, Engilbert, Steinberg, Stacy, Stefansson, Hreinn, Stefansson, Kari, Kapur-Pojskic, Lejla, Oruc, Liliana, Rivas, Fabio, Mayoral, Fermín, Chuchalin, Alexander, Babadjanova, Gulja, Tiganov, Alexander S., Pantelejeva, Galina, Abramova, Lilia I., Grigoroiu-Serbanescu, Maria, Diaconu, Carmen C., Czerski, Piotr M., Hauser, Joanna, Zimmer, Andreas, Lathrop, Mark, Schulze, Thomas G., Wienker, Thomas F., Schumacher, Johannes, Maier, Wolfgang, Propping, Peter, Rietschel, Marcella, Nöthen, Markus M.

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Autosomal-dominant non-syndromic anal atresia: sequencing of candidate genes, array-based molecular karyotyping, and review of the literature by Schramm, Charlotte, Draaken, Markus, Tewes, Gabriel, Bartels, Enrika, Schmiedeke, Eberhard, Märzheuser, Stefanie, Grasshoff-Derr, Sabine, Hosie, Stuart, Holland-Cunz, Stefan, Priebe, Lutz, Kreiß-Nachtsheim, Martina, Hoffmann, Per, Aretz, Stefan, Nöthen, Markus M., Reutter, Heiko, Ludwig, Michael

“…Introduction Anorectal malformations (ARM) range from mild anal to severe anorectal anomalies. Approximately 50% are estimated to be non-syndromic with…”
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De novo duplication of 18p11.21-18q12.1 in a female with anorectal malformation by Schramm, Charlotte, Draaken, Markus, Bartels, Enrika, Boemers, Thomas M., Schmiedeke, Eberhard, Grasshoff-Derr, Sabine, Märzheuser, Stefanie, Hosie, Stuart, Holland-Cunz, Stefan, Baudisch, Friederike, Priebe, Lutz, Hoffmann, Per, Zink, Alexander M., Engels, Hartmut, Brockschmidt, Felix F., Aretz, Stefan, Nöthen, Markus M., Ludwig, Michael, Reutter, Heiko

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