Search Results - "Pride, Michael C"
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Sex differences in social interaction behavior following social defeat stress in the monogamous California mouse (Peromyscus californicus)
Published in PloS one (25-02-2011)“…Stressful life experiences are known to be a precipitating factor for many mental disorders. The social defeat model induces behavioral responses in rodents…”
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Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism
Published in Molecular autism (15-06-2017)“…Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral…”
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Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome
Published in Human molecular genetics (15-10-2017)“…Maternally derived copy number gains of human chromosome 15q11.2-q13.3 (Dup15q syndrome or Dup15q) cause intellectual disability, epilepsy, developmental…”
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Developmental social communication deficits in the Shank3 rat model of phelan‐mcdermid syndrome and autism spectrum disorder
Published in Autism research (01-04-2018)“…Mutations in the SHANK3 gene have been discovered in autism spectrum disorder (ASD), and the intellectual disability, Phelan‐McDermid Syndrome. This study…”
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Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering
Published in Human molecular genetics (15-05-2017)“…Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in the gene encoding methyl CpG binding protein 2 (MeCP2) that occur…”
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SynDIG4/Prrt1 Is Required for Excitatory Synapse Development and Plasticity Underlying Cognitive Function
Published in Cell reports (Cambridge) (27-02-2018)“…Altering AMPA receptor (AMPAR) content at synapses is a key mechanism underlying the regulation of synaptic strength during learning and memory. Previous work…”
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Effects of kappa opioid receptors on conditioned place aversion and social interaction in males and females
Published in Behavioural brain research (01-04-2014)“…•Low doses of kappa opioid receptor agonist induced place aversion in females but not males.•Acute effects of kappa agonist on social interaction behavior are…”
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Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats
Published in Translational psychiatry (17-08-2020)“…Epidemiological studies consistently implicate traffic-related air pollution (TRAP) and/or proximity to heavily trafficked roads as risk factors for…”
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Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism
Published in Molecular psychiatry (01-11-2020)“…Immune dysregulation has been noted consistently in individuals with autism spectrum disorder (ASD) and their families, including the presence of…”
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Germline Chd8 haploinsufficiency alters brain development in mouse
Published in Nature neuroscience (01-08-2017)“…Strong genetic evidence points to a significant role for heterozygous mutations to general chromatin remodeling factors, such as CHD8, in autism. Gompers et al…”
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Cognitive deficits in the Snord116 deletion mouse model for Prader-Willi syndrome
Published in Neurobiology of learning and memory (01-11-2019)“…•A lack of the gene cluster SNORD116 may be responsible for some aspects of PWS.•Heterozygous Snord116 mutation mice had learning and memory deficits in three…”
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Surgical restabilization reduces the progression of post-traumatic osteoarthritis initiated by ACL rupture in mice
Published in Osteoarthritis and cartilage (01-08-2024)“…People who sustain joint injuries such as anterior cruciate ligament (ACL) rupture often develop post-traumatic osteoarthritis (PTOA). In human patients, ACL…”
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Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size
Published in Brain (London, England : 1878) (01-09-2019)“…The underpinnings of mild to moderate neurodevelopmental delay remain elusive, often leading to late diagnosis and interventions. Here, we present data on…”
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MeCP2 isoform e1 mutant mice recapitulate motor and metabolic phenotypes of Rett syndrome
Published in Human molecular genetics (01-12-2018)“…Abstract Mutations in the X-linked gene MECP2 cause the majority of Rett syndrome (RTT) cases. Two differentially spliced isoforms of exons 1 and 2 (MeCP2-e1…”
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