Search Results - "Prezioso, Samantha M."
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Control of a programmed cell death pathway in Pseudomonas aeruginosa by an antiterminator
Published in Nature communications (17-03-2021)“…In Pseudomonas aeruginosa the alp system encodes a programmed cell death pathway that is switched on in a subset of cells in response to DNA damage and is…”
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Quantification of ricin, RCA and comparison of enzymatic activity in 18 Ricinus communis cultivars by isotope dilution mass spectrometry
Published in Toxicon (Oxford) (01-03-2015)“…The seeds of the Ricinus communis (Castor bean) plant are the source of the economically important commodity castor oil. Castor seeds also contain the proteins…”
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Elfamycins: inhibitors of elongation factor‐Tu
Published in Molecular microbiology (01-10-2017)“…Summary Elfamycins are a relatively understudied group of antibiotics that target the essential process of translation through impairment of EF‐Tu function…”
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Structural Basis for Virulence Activation of Francisella tularensis
Published in Molecular cell (07-01-2021)“…The bacterium Francisella tularensis (Ft) is one of the most infectious agents known. Ft virulence is controlled by a unique combination of transcription…”
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Substrate recognition by the Pseudomonas aeruginosa EF-Tu–modifying methyltransferase EftM
Published in The Journal of biological chemistry (27-12-2019)“…The opportunistic bacterial pathogen Pseudomonas aeruginosa is a leading cause of serious infections in individuals with cystic fibrosis, compromised immune…”
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Trimethylation of Elongation Factor-Tu by the Dual Thermoregulated Methyltransferase EftM Does Not Impact Its Canonical Function in Translation
Published in Scientific reports (05-03-2019)“…The Pseudomonas aeruginosa methyltransferase EftM trimethylates elongation factor-Tu (EF-Tu) on lysine 5 to form a post-translational modification important…”
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Pseudomonas aeruginosa EftM Is a Thermoregulated Methyltransferase
Published in The Journal of biological chemistry (12-02-2016)“…Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that trimethylates elongation factor-thermo-unstable (EF-Tu) on lysine 5. Lysine 5 methylation…”
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Comparison of biosensor platforms for surface plasmon resonance based detection of paralytic shellfish toxins
Published in Talanta (Oxford) (15-07-2011)“…Paralytic shellfish poisoning (PSP) toxins are produced by certain marine dinoflagellates and may accumulate in bivalve molluscs through filter feeding. The…”
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A High-Throughput Diagnostic Method for Measuring Human Exposure to Organophosphorus Nerve Agents
Published in Analytical chemistry (Washington) (06-11-2012)“…An automated high-throughput immunomagnetic separation (IMS) method for diagnosing exposure to the organophosphorus nerve agents (OPNAs) sarin (GB),…”
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Developing improved immunoassays for paralytic shellfish toxins: The need for multiple, superior antibodies
Published in Talanta (Oxford) (15-09-2012)“…Paralytic shellfish toxins (PSTs) are a risk to humans upon consumption of contaminated seafood. The PST family is comprised of more than twenty congeners,…”
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High-Throughput Immunomagnetic Scavenging Technique for Quantitative Analysis of Live VX Nerve Agent in Water, Hamburger, and Soil Matrixes
Published in Analytical chemistry (Washington) (20-11-2012)“…We have developed a novel immunomagnetic scavenging technique for extracting cholinesterase inhibitors from aqueous matrixes using biological targeting and…”
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