Search Results - "Prexl, Andrea"
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Differential gene regulation in DAPT-treated Hydra reveals candidate direct Notch signalling targets
Published in Journal of cell science (01-08-2021)“…ABSTRACT In Hydra, Notch inhibition causes defects in head patterning and prevents differentiation of proliferating nematocyte progenitor cells into mature…”
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The putative Notch ligand HyJagged is a transmembrane protein present in all cell types of adult Hydra and upregulated at the boundary between bud and parent
Published in BMC cell biology (07-09-2011)“…The Notch signalling pathway is conserved in pre-bilaterian animals. In the Cnidarian Hydra it is involved in interstitial stem cell differentiation and in…”
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3
Notch-signalling is required for head regeneration and tentacle patterning in Hydra
Published in Developmental biology (01-11-2013)“…Local self-activation and long ranging inhibition provide a mechanism for setting up organising regions as signalling centres for the development of structures…”
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4
Notch signalling defines critical boundary during budding in Hydra
Published in Developmental biology (01-08-2010)“…Boundary formation is an important mechanism of development and has been studied in a number of bilaterian model organisms where it is often controlled by…”
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Journal Article