Search Results - "Prevotat, Anne"
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The airway microbiota in cystic fibrosis: a complex fungal and bacterial community--implications for therapeutic management
Published in PloS one (27-04-2012)“…Given the polymicrobial nature of pulmonary infections in patients with cystic fibrosis (CF), it is essential to enhance our knowledge on the composition of…”
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Respiratory mycobiome and suggestion of inter-kingdom network during acute pulmonary exacerbation in cystic fibrosis
Published in Scientific reports (27-02-2020)“…Lung infections play a critical role in cystic fibrosis (CF) pathogenesis. CF respiratory tract is now considered to be a polymicrobial niche and advances in…”
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3
The immediate effects of a single autogenic drainage session on ventilatory mechanics in adult subjects with cystic fibrosis
Published in PloS one (29-03-2018)“…The aim of this study was to gain insight into the physiological changes occurring in subjects with cystic fibrosis (CF) after autogenic drainage (AD). Changes…”
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Impact of Achromobacter xylosoxidans isolation on the respiratory function of adult patients with cystic fibrosis
Published in ERJ open research (01-10-2019)“…The prevalence of lung isolation in cystic fibrosis (CF) patients has increased, but the impact on lung function is controversial. The aim of this study was to…”
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Predictors of massive haemoptysis after a first episode of mild-to-moderate haemoptysis in patients with cystic fibrosis
Published in ERJ open research (01-07-2020)“…The main cause of death of cystic fibrosis (CF) patients is respiratory disease due to secondary infections, haemoptysis, pneumothorax, and respiratory failure…”
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6
Optimized approach for the identification of highly efficient correctors of nonsense mutations in human diseases
Published in PloS one (13-11-2017)“…About 10% of patients with a genetic disease carry a nonsense mutation causing their pathology. A strategy for correcting nonsense mutations is premature…”
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Use of 2,6-diaminopurine as a potent suppressor of UGA premature stop codons in cystic fibrosis
Published in Molecular therapy (05-04-2023)“…Nonsense mutations are responsible for around 10% of cases of genetic diseases, including cystic fibrosis. 2,6-diaminopurine (DAP) has recently been shown to…”
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8
Virus and cystic fibrosis: Rhinoviruses are associated with exacerbations in adult patients
Published in Journal of clinical virology (01-06-2014)“…Abstract Background Few studies have suggested the potential role of respiratory viruses in cystic fibrosis (CF) exacerbation, but their real impact is…”
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Real-life initiation of lumacaftor/ivacaftor combination in adults with cystic fibrosis homozygous for the Phe508del CFTR mutation and severe lung disease
Published in Journal of cystic fibrosis (01-05-2017)“…Abstract Objective To investigate the short-term adverse events and effectiveness of lumacaftor/ivacaftor combination treatment in adults with cystic fibrosis…”
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10
Toward the Standardization of Mycological Examination of Sputum Samples in Cystic Fibrosis: Results from a French Multicenter Prospective Study
Published in Mycopathologia (1975) (01-02-2018)“…Fungal respiratory colonization of cystic fibrosis (CF) patients emerges as a new concern; however, the heterogeneity of mycological protocols limits…”
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11
Determinants of exercise capacity in cystic fibrosis patients with mild-to-moderate lung disease
Published in BMC pulmonary medicine (30-04-2014)“…Adult patients with cystic fibrosis (CF) frequently have reduced exercise tolerance, which is multifactorial but mainly due to bronchial obstruction. The aim…”
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Rapid Improvement After Starting Elexacaftor-tezacaftor-ivacaftor in Patients with Cystic Fibrosis and Advanced Pulmonary Disease
Published in American journal of respiratory and critical care medicine (01-07-2021)“…Elexacaftor-tezacaftor-ivacaftor is a cystic fibrosis transmembrane conductance regulator modulator combination, developed for cystic fibrosis (CF) patients…”
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13
Haemodynamically proven pulmonary hypertension in a patient with GATA2 deficiency-associated pulmonary alveolar proteinosis and fibrosis
Published in The European respiratory journal (01-05-2017)“…We read with great interest the article by Ballerie et al. [1], which describes the occurrence of pulmonary alveolar proteinosis and fibrosis in a patient with…”
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14
Real-Life Safety and Effectiveness of Lumacaftor-Ivacaftor in Patients with Cystic Fibrosis
Published in American journal of respiratory and critical care medicine (15-01-2020)“…Lumacaftor-ivacaftor is a CFTR (cystic fibrosis transmembrane conductance regulator) modulator combination recently approved for patients with cystic fibrosis…”
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15
Fertility of women with cystic fibrosis: a French survey
Published in Reproductive biomedicine online (01-09-2019)“…Research question: Although the impact of cystic fibrosis on male fertility is well known, very few studies have investigated its effect on female fertility…”
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16
Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial
Published in American journal of respiratory and critical care medicine (15-12-2019)“…Targeted lung denervation (TLD) is a bronchoscopic radiofrequency ablation therapy for chronic obstructive pulmonary disease (COPD), which durably disrupts…”
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Omalizumab treatment for allergic bronchopulmonary aspergillosis in young patients with cystic fibrosis
Published in Respiratory medicine (01-12-2017)“…Allergic bronchopulmonary aspergillosis (ABPA) is a severe lung disease complication caused by an Aspergillus fumigatus-induced hypersensitivity that affects…”
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18
Early glucose abnormalities revealed by continuous glucose monitoring associate with lung function decline in cystic fibrosis: A five-year prospective study
Published in Journal of diabetes and its complications (01-04-2024)“…Cystic fibrosis related diabetes (CFRD) is commonly associated with declining lung function and nutritional status. We aimed to evaluate the pulmonary impact…”
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Effects of a Partially Supervised Conditioning Program in Cystic Fibrosis: An International Multicenter, Randomized Controlled Trial (ACTIVATE-CF)
Published in American journal of respiratory and critical care medicine (01-02-2022)“…The long-term effects of vigorous physical activity (PA) on lung function in cystic fibrosis are unclear. To evaluate effects of a 12-month partially…”
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20
Long-term computed tomographic changes in cystic fibrosis patients treated with ivacaftor
Published in The European respiratory journal (01-07-2016)“…Cystic fibrosis (CF) patients with gating mutations in the gene coding for the CF transmembrane conductance regulator (CFTR) protein have been the first to…”
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