Search Results - "Prevost, Toby A"

Probability of an Obese Person Attaining Normal Body Weight: Cohort Study Using Electronic Health Records by Fildes, Alison, Charlton, Judith, Rudisill, Caroline, Littlejohns, Peter, Prevost, A Toby, Gulliford, Martin C

“…We examined the probability of an obese person attaining normal body weight. We drew a sample of individuals aged 20 years and older from the United Kingdom's…”
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Association between high serum total cortisol concentrations and mortality from COVID-19 by Tan, Tricia, Khoo, Bernard, Mills, Edouard G, Phylactou, Maria, Patel, Bijal, Eng, Pei C, Thurston, Layla, Muzi, Beatrice, Meeran, Karim, Prevost, A Toby, Comninos, Alexander N, Abbara, Ali, Dhillo, Waljit S

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Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation for best corrected visual acuity in patients with proliferative diabetic retinopathy at 52 weeks (CLARITY): a multicentre, single-blinded, randomised, controlled, phase 2b, non-inferiority trial by Sivaprasad, Sobha, Prof, Prevost, A Toby, Prof, Vasconcelos, Joana C, MSc, Riddell, Amy, PhD, Murphy, Caroline, MS, Kelly, Joanna, MSc, Bainbridge, James, Prof, Tudor-Edwards, Rhiannon, Prof, Hopkins, David, FRCP, Hykin, Philip, FRCOphth

“…Summary Background Proliferative diabetic retinopathy is the most common cause of severe sight impairment in people with diabetes. Proliferative diabetic…”
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Combined GLP-1, Oxyntomodulin, and Peptide YY Improves Body Weight and Glycemia in Obesity and Prediabetes/Type 2 Diabetes: A Randomized, Single-Blinded, Placebo-Controlled Study by Behary, Preeshila, Tharakan, George, Alexiadou, Kleopatra, Johnson, Nicholas, Wewer Albrechtsen, Nicolai J, Kenkre, Julia, Cuenco, Joyceline, Hope, David, Anyiam, Oluwaseun, Choudhury, Sirazum, Alessimii, Haya, Poddar, Ankur, Minnion, James, Doyle, Chedie, Frost, Gary, Le Roux, Carel, Purkayastha, Sanjay, Moorthy, Krishna, Dhillo, Waljit, Holst, Jens J, Ahmed, Ahmed R, Prevost, A Toby, Bloom, Stephen R, Tan, Tricia M

“…Roux-en-Y gastric bypass (RYGB) augments postprandial secretion of glucagon-like peptide 1 (GLP-1), oxyntomodulin (OXM), and peptide YY (PYY). Subcutaneous…”
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A Highly Tailored Text and Voice Messaging Intervention to Improve Medication Adherence in Patients With Either or Both Hypertension and Type 2 Diabetes in a UK Primary Care Setting: Feasibility Randomized Controlled Trial of Clinical Effectiveness by Kassavou, Aikaterini, Mirzaei, Venus, Brimicombe, James, Edwards, Simon, Massou, Efthalia, Prevost, A Toby, Griffin, Simon, Sutton, Stephen

“…The efficacy of a highly tailored digital intervention to support medication adherence and feasibility to support clinical effectiveness as an adjunct to the…”
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Screening for type 2 diabetes and population mortality over 10 years (ADDITION-Cambridge): a cluster-randomised controlled trial by Simmons, Rebecca K, PhD, Echouffo-Tcheugui, Justin B, PhD, Sharp, Stephen J, MSc, Sargeant, Lincoln A, PhD, Williams, Kate M, PhD, Prevost, A Toby, Prof, Kinmonth, Ann Louise, Prof, Wareham, Nicholas J, Prof, Griffin, Simon J, Dr

“…Summary Background The increasing prevalence of type 2 diabetes poses a major public health challenge. Population-based screening and early treatment for type…”
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Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials by Santhakumaran, Shalini, Gordon, Anthony, Prevost, A Toby, O'Kane, Cecilia, McAuley, Daniel F, Shankar-Hari, Manu

“…Randomised controlled trials (RCTs) enrolling patients with sepsis or acute respiratory distress syndrome (ARDS) generate heterogeneous trial populations…”
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Researchers' experiences of the design and conduct challenges associated with parallel-group cluster-randomised trials and views on a novel open-cohort design by Surr, Claire, Marsden, Laura, Griffiths, Alys, Cox, Sharon, Fossey, Jane, Martin, Adam, Prevost, A Toby, Walshe, Catherine, Walwyn, Rebecca

“…Two accepted designs exist for parallel-group cluster-randomised trials (CRTs). Closed-cohort designs follow the same individuals over time with a single…”
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Randomized controlled trial to assess the short-term effectiveness of tailored web- and text-based facilitation of smoking cessation in primary care (iQuit in Practice) by Naughton, Felix, Jamison, James, Boase, Sue, Sloan, Melanie, Gilbert, Hazel, Prevost, A. Toby, Mason, Dan, Smith, Susan, Brimicombe, James, Evans, Robert, Sutton, Stephen

“…Aims To estimate the short‐term effectiveness, feasibility and acceptability of a smoking cessation intervention (the iQuit system) that consists of tailored…”
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Impact of community based peer support in type 2 diabetes: a cluster randomised controlled trial of individual and/or group approaches by Simmons, David, Prevost, A Toby, Bunn, Chris, Holman, Daniel, Parker, Richard A, Cohn, Simon, Donald, Sarah, Paddison, Charlotte A M, Ward, Candice, Robins, Peter, Graffy, Jonathan

“…Diabetes peer support, where one person with diabetes helps guide and support others, has been proposed as a way to improve diabetes management. We have tested…”
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Adjusting for verification bias in diagnostic accuracy measures when comparing multiple screening tests - an application to the IP1-PROSTAGRAM study by Day, Emily, Eldred-Evans, David, Prevost, A Toby, Ahmed, Hashim U, Fiorentino, Francesca

“…Novel screening tests used to detect a target condition are compared against either a reference standard or other existing screening methods. However, as it is…”
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Development and validation of resource-driven risk prediction models for incident chronic kidney disease in type 2 diabetes by Gurudas, Sarega, Nugawela, Manjula, Prevost, A. Toby, Sathish, Thirunavukkarasu, Mathur, Rohini, Rafferty, J. M., Blighe, Kevin, Rajalakshmi, Ramachandran, Mohan, Anjana R., Saravanan, Jebarani, Majeed, Azeem, Mohan, Viswanthan, Owens, David R., Robson, John, Sivaprasad, Sobha

“…Prediction models for population-based screening need, for global usage, to be resource-driven, involving predictors that are affordably resourced. Here, we…”
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Prevalence of Abnormal Lipid Profiles and the Relationship With the Development of Microalbuminuria in Adolescents With Type 1 Diabetes by Loredana Marcovecchio, M, Neil Dalton, R, Toby Prevost, A, Acerini, Carlo L, Barrett, Timothy G, Cooper, Jason D, Edge, Julie, Neil, Andrew, Shield, Julian, Widmer, Barry, Todd, John A, Dunger, David B

“…OBJECTIVE: To explore the prevalence of lipid abnormalities and their relationship with albumin excretion and microalbuminuria in adolescents with type 1…”
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A systematic review identifying common data items in neonatal trials and assessing their completeness in routinely recorded United Kingdom national neonatal data by Jawad, Sena, Modi, Neena, Prevost, A Toby, Gale, Chris

“…We aimed to test whether a common set of key data items reported across high-impact neonatal clinical trials could be identified, and to quantify their…”
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Intravitreal ranibizumab versus aflibercept versus bevacizumab for macular oedema due to central retinal vein occlusion: the LEAVO non-inferiority three-arm RCT by Hykin, Philip, Prevost, A Toby, Sivaprasad, Sobha, Vasconcelos, Joana C, Murphy, Caroline, Kelly, Joanna, Ramu, Jayashree, Alshreef, Abualbishr, Flight, Laura, Pennington, Rebekah, Hounsome, Barry, Lever, Ellen, Metry, Andrew, Poku, Edith, Yang, Yit, Harding, Simon P, Lotery, Andrew, Chakravarthy, Usha, Brazier, John

“…Background Licensed ranibizumab (0.5 mg/0.05 ml Lucentis ® ; Novartis International AG, Basel, Switzerland) and aflibercept (2 mg/0.05 ml Eylea ® ; Bayer AG,…”
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Electronically delivered interventions to reduce antibiotic prescribing for respiratory infections in primary care: cluster RCT using electronic health records and cohort study by Gulliford, Martin C, Juszczyk, Dorota, Prevost, A Toby, Soames, Jamie, McDermott, Lisa, Sultana, Kirin, Wright, Mark, Fox, Robin, Hay, Alastair D, Little, Paul, Moore, Michael, Yardley, Lucy, Ashworth, Mark, Charlton, Judith

“…Unnecessary prescribing of antibiotics in primary care is contributing to the emergence of antimicrobial drug resistance. To develop and evaluate a…”
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Evaluation of a very brief pedometer-based physical activity intervention delivered in NHS Health Checks in England: The VBI randomised controlled trial by Hardeman, Wendy, Mitchell, Joanna, Pears, Sally, Van Emmenis, Miranda, Theil, Florence, Gc, Vijay S, Vasconcelos, Joana C, Westgate, Kate, Brage, Søren, Suhrcke, Marc, Griffin, Simon J, Kinmonth, Ann Louise, Wilson, Edward C F, Prevost, A Toby, Sutton, Stephen

“…The majority of people do not achieve recommended levels of physical activity. There is a need for effective, scalable interventions to promote activity…”
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Psychological impact of screening for type 2 diabetes: controlled trial and comparative study embedded in the ADDITION (Cambridge) randomised controlled trial by Eborall, Helen C, Griffin, Simon J, Prevost, A Toby, Kinmonth, Ann-Louise, French, David P, Sutton, Stephen

“…Objective To quantify the psychological impact of primary care based stepwise screening for type 2 diabetes.Design Controlled trial and comparative study…”
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Randomised controlled trial of a just-in-time adaptive intervention (JITAI) smoking cessation smartphone app: the Quit Sense feasibility trial protocol by Naughton, Felix, Brown, Chloë, High, Juliet, Notley, Caitlin, Mascolo, Cecilia, Coleman, Tim, Barton, Garry, Shepstone, Lee, Sutton, Stephen, Prevost, A Toby, Crane, David, Greaves, Felix, Hope, Aimie

“…IntroductionA lapse (any smoking) early in a smoking cessation attempt is strongly associated with reduced success. A substantial proportion of lapses are due…”
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The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection-study protocol for a two-stage randomised phase II trial by Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C, Caskey, Marina, Frater, John, Fidler, Sarah

“…Antiretroviral therapy (ART) has led to dramatic improvements in survival for people living with HIV, but is unable to cure infection, or induce viral control…”
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