Search Results - "Previdi, Sara"
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Modeling Staphylococcus epidermidis-Induced Non-Unions: Subclinical and Clinical Evidence in Rats
Published in PloS one (21-01-2016)“…S. epidermidis is one of the leading causes of orthopaedic infections associated with biofilm formation on implant devices. Open fractures are at risk of S…”
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2
Diabetic mouse model of orthopaedic implant-related Staphylococcus aureus infection
Published in PloS one (20-06-2013)“…Periprosthetic bacterial infections represent one of the most challenging orthopaedic complications that often require implant removal and surgical debridement…”
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3
Combination of the c-Met inhibitor tivantinib and zoledronic acid prevents tumor bone engraftment and inhibits progression of established bone metastases in a breast xenograft model
Published in PloS one (18-11-2013)“…Bone is the most common metastatic site for breast cancer. There is a significant need to understand the molecular mechanisms controlling the engraftment and…”
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4
Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency
Published in Stem cell research & therapy (27-07-2017)“…Argininosuccinate synthase (ASS)1 is a urea cycle enzyme that catalyzes the conversion of citrulline and aspartate to argininosuccinate. Mutations in the ASS1…”
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5
Does PGE₁ vasodilator prevent orthopaedic implant-related infection in diabetes? Preliminary results in a mouse model
Published in PloS one (09-04-2014)“…Implant-related infections are characterized by bacterial colonization and biofilm formation on the prosthesis. Diabetes represents one of the risk factors…”
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6
Longitudinal tracking of triple labeled umbilical cord derived mesenchymal stromal cells in a mouse model of Amyotrophic Lateral Sclerosis
Published in Stem cell research (01-07-2015)“…The translational potential of cell therapy to humans requires a deep knowledge of the interaction between transplanted cells and host tissues. In this study,…”
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Questioning the oncogenic role of ΔNp73α in different cell lines expressing p53 or not
Published in Cancer biology & therapy (01-07-2006)“…The recent finding that the 1p36.3 locus gene encodes an array of different p73 isoforms with apparently distinct and sometimes opposing cellular functions,…”
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8
The Healthcare Relationship during the Second Wave of the COVID-19 Pandemic: A Qualitative Study in the Emergency Department of an Italian Hospital
Published in International journal of environmental research and public health (23-01-2023)“…The COVID-19 pandemic had an impact not only on people's lives but also on the healthcare system. This study aimed to investigate the healthcare relationship…”
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9
In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed
Published in Angiogenesis (London) (01-11-2022)“…With recent progress in modeling liver organogenesis and regeneration, the lack of vasculature is becoming the bottleneck in progressing our ability to model…”
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10
Organ Distribution and Bone Tropism of Cellulose Nanocrystals in Living Mice
Published in Biomacromolecules (14-09-2015)“…Their physicochemical properties and relatively low cost make cellulose nanocrystals (CNCs) a potential candidate for future large-scale production in many…”
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11
Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and β-catenin/Wnt pathways
Published in European journal of cancer (1990) (01-06-2010)“…Abstract To clarify the reciprocal interaction between human-breast cancer metastatic cells and bone microenvironment, we studied the influence of HGF/Met…”
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12
Breast cancer-derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown
Published in Molecular cancer therapeutics (01-01-2012)“…Breast cancer exhibits a propensity to metastasize to bone, resulting in debilitating skeletal complications associated with significant morbidity and poor…”
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13
Phospholipase Cγ1 Is Required for Metastasis Development and Progression
Published in Cancer research (Chicago, Ill.) (15-12-2008)“…Abstract Cell motility and invasion play an essential role in the development of metastasis. Evidence suggests that the enzyme phospholipase Cγ1 (PLCγ1) may be…”
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14
Direct but not indirect co-culture with osteogenically differentiated human bone marrow stromal cells increases RANKL/OPG ratio in human breast cancer cells generating bone metastases
Published in Molecular cancer (21-10-2014)“…Bone metastases arise in nearly 70% of patients with advanced breast cancer, but the complex metastatic process has not been completely clarified yet…”
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15
In Vivo Fate of Avidin-Nucleic Acid Nanoassemblies as Multifunctional Diagnostic Tools
Published in ACS nano (28-01-2014)“…This study describes the formulation optimization and body-cell distribution and clearance in mice of a dually fluorescent biodegradable poly avidin…”
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16
Multiple drug delivery hydrogel system for spinal cord injury repair strategies
Published in Journal of controlled release (30-04-2012)“…The multifactorial pathological progress of spinal cord injury (SCI) is probably the main reason behind the absence of efficient therapeutic approaches. Hence,…”
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Inhibition of Sp1-dependent transcription and antitumor activity of the new aureolic acid analogues mithramycin SDK and SK in human ovarian cancer xenografts
Published in Gynecologic oncology (01-08-2010)“…Abstract Objective Increased activity of Sp family of transcription factors is a frequent and critical event in cancer development and progression. Genes…”
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18
Does [PGE.sub.1] vasodilator prevent orthopaedic implant-related infection in diabetes? Preliminary results in a mouse model
Published in PloS one (01-04-2014)“…Background: Implant-related infections are characterized by bacterial colonization and biofilm formation on the prosthesis. Diabetes represents one of the risk…”
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Journal Article -
19
In vivo evaluation of bone deposition in macroporous titanium implants loaded with mesenchymal stem cells and strontium-enriched hydrogel
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-02-2015)“…Bone-implant integration represents a major requirement to grant implant stability and reduce the risk of implant loosening. This study investigates the effect…”
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In vivo evaluation of the role of DNp73α protein in regulating the p53‐dependent apoptotic pathway after treatment with cytotoxic drugs
Published in International journal of cancer (01-02-2007)“…The amino terminus truncated p73 isoform, ΔNp73α, shows dominant negative behavior toward TAp73 and wild‐type p53, and has oncogenic potential. By contrast, we…”
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