Search Results - "Pretz, Dominik"
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Hyperleptinemia as a contributing factor for the impairment of glucose intolerance in obesity
Published in The FASEB journal (01-02-2021)“…Obesity has emerged as a major risk factor for insulin resistance leading to the development of type 2 diabetes (T2D). The condition is characterized by high…”
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Intestinal Barrier Function and the Gut Microbiome Are Differentially Affected in Mice Fed a Western-Style Diet or Drinking Water Supplemented with Fructose
Published in The Journal of nutrition (01-05-2017)“…The consumption of a Western-style diet (WSD) and high fructose intake are risk factors for metabolic diseases. The underlying mechanisms are largely unclear…”
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3
Timing Matters: Circadian Effects on Energy Homeostasis and Alzheimer’s Disease
Published in Trends in endocrinology and metabolism (01-02-2019)“…Metabolic syndrome and Alzheimer’s disease (AD) are two major health issues in modern society causing an extraordinary financial burden for the global…”
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4
Central inhibition of IKKβ/NF-κB signaling attenuates high-fat diet-induced obesity and glucose intolerance
Published in Diabetes (New York, N.Y.) (01-06-2015)“…Metabolic inflammation in the central nervous system might be causative for the development of overnutrition-induced metabolic syndrome and related disorders,…”
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Conditional Deletion of β-Catenin in the Mediobasal Hypothalamus Impairs Adaptive Energy Expenditure in Response to High-Fat Diet and Exacerbates Diet-Induced Obesity
Published in The Journal of neuroscience (03-04-2024)“…β-Catenin is a bifunctional molecule that is an effector of the wingless-related integration site (Wnt) signaling to control gene expression and contributes to…”
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Lack of liver steatosis in germ-free mice following hypercaloric diets
Published in European journal of nutrition (01-08-2019)“…Purpose Experimental liver steatosis induced by overfeeding is associated with enhanced gut permeability and endotoxin translocation to the liver. We examined…”
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A dahlia flower extract has antidiabetic properties by improving insulin function in the brain
Published in Life metabolism (01-08-2023)“…Abstract Butein, a rare chalcone found in the toxic plant Toxicodendron vernicifluum, has been shown to regulate glucose homeostasis via inhibition of the…”
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Central Inhibition of IKK[Beta]/NF-[kappa]B Signaling Attenuates High-Fat Diet-Induced Obesity and Glucose Intolerance
Published in Diabetes (New York, N.Y.) (01-06-2015)“…Metabolic inflammation in the central nervous system might be causative for the development of overnutrition-induced metabolic syndrome and related disorders,…”
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Journal Article