Search Results - "Pretto, Carla"

Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection by Qiao, Yuanyuan, Wotring, Jesse W, Zhang, Charles J, Jiang, Xia, Xiao, Lanbo, Watt, Andy, Gattis, Danielle, Scandalis, Eli, Freier, Susan, Zheng, Yang, Pretto, Carla D, Ellison, Stephanie J, Swayze, Eric E, Guo, Shuling, Sexton, Jonathan Z, Chinnaiyan, Arul M

“…Although the COVID-19 pandemic began over three years ago, the virus responsible for the disease, SARS-CoV-2, continues to infect people across the globe. As…”
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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19 by Mirabelli, Carmen, Wotring, Jesse W., Zhang, Charles J., McCarty, Sean M., Fursmidt, Reid, Pretto, Carla D., Qiao, Yuanyuan, Zhang, Yuping, Frum, Tristan, Kadambi, Namrata S., Amin, Anya T., O’Meara, Teresa R., Spence, Jason R., Huang, Jessie, Alysandratos, Konstantinos D., Kotton, Darrell N., Handelman, Samuel K., Wobus, Christiane E., Weatherwax, Kevin J., Mashour, George A., O’Meara, Matthew J., Chinnaiyan, Arul M., Sexton, Jonathan Z.

“…The global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the associated disease COVID-19, requires therapeutic interventions…”
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Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2 by Qiao, Yuanyuan, Wang, Xiao-Ming, Mannan, Rahul, Pitchiaya, Sethuramasundaram, Zhang, Yuping, Wotring, Jesse W., Xiao, Lanbo, Robinson, Dan R., Wu, Yi-Mi, Tien, Jean Ching-Yi, Cao, Xuhong, Simko, Stephanie A., Apel, Ingrid J., Bawa, Pushpinder, Kregel, Steven, Narayanan, Sathiya P., Raskind, Gregory, Ellison, Stephanie J., Parolia, Abhijit, Zelenka-Wang, Sylvia, McMurry, Lisa, Su, Fengyun, Wang, Rui, Cheng, Yunhui, Delekta, Andrew D., Mei, Zejie, Pretto, Carla D., Wang, Shaomeng, Mehra, Rohit, Sexton, Jonathan Z., Chinnaiyan, Arul M.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, employs two key host proteins to gain entry and replicate…”
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EGFR Interacts with the Fusion Protein of Respiratory Syncytial Virus Strain 2-20 and Mediates Infection and Mucin Expression by Currier, Michael G, Lee, Sujin, Stobart, Christopher C, Hotard, Anne L, Villenave, Remi, Meng, Jia, Pretto, Carla D, Shields, Michael D, Nguyen, Minh Trang, Todd, Sean O, Chi, Michael H, Hammonds, Jason, Krumm, Stefanie A, Spearman, Paul, Plemper, Richard K, Sakamoto, Kaori, Peebles, Jr, R Stokes, Power, Ultan F, Moore, Martin L

“…Respiratory syncytial virus (RSV) is the major cause of viral lower respiratory tract illness in children. In contrast to the RSV prototypic strain A2,…”
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Self-Assembled STING-Activating Coordination Nanoparticles for Cancer Immunotherapy and Vaccine Applications by Sun, Xiaoqi, Huang, Xuehui, Park, Kyung Soo, Zhou, Xingwu, Kennedy, Andrew A., Pretto, Carla D., Wu, Qi, Wan, Ziye, Xu, Yao, Gong, Wang, Sexton, Jonathan Z., Tai, Andrew W., Lei, Yu Leo, Moon, James J.

“…The cGAS-STING pathway plays a crucial role in innate immune activation against cancer and infections, and STING agonists based on cyclic dinucleotides (CDN)…”
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Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium by Singh, Pawan Kumar, Khatri, Indu, Jha, Alokkumar, Pretto, Carla D., Spindler, Katherine R., Arumugaswami, Vaithilingaraja, Giri, Shailendra, Kumar, Ashok, Bhasin, Manoj K.

“…Previously, we reported that Zika virus (ZIKV) causes ocular complications such as chorioretinal atrophy, by infecting cells lining the blood-retinal barrier,…”
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Oral Vaccination with Replication-Competent Adenovirus in Mice Reveals Dissemination of the Viral Vaccine beyond the Gastrointestinal Tract by Goffin, Emeline, Javaux, Justine, Destexhe, Eric, Pretto, Carla D, Spindler, Katherine R, Machiels, Bénédicte, Gillet, Laurent

“…Since the 1970s, replication-competent human adenoviruses 4 and 7 have been used as oral vaccines to protect U.S. soldiers against the severe respiratory…”
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The effect of ultraviolet C radiation against different N95 respirators inoculated with SARS-CoV-2 by Ozog, David M., Sexton, Jonathan Z., Narla, Shanthi, Pretto-Kernahan, Carla D., Mirabelli, Carmen, Lim, Henry W., Hamzavi, Iltefat H., Tibbetts, Robert J., Mi, Qing-Sheng

“…•Ultraviolet C at a dose of 1.5 J/cm2 to both sides is effective on some models of N95s.•Straps may require additional disinfection to decontaminate…”
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Proxalutamide reduces SARS-CoV-2 infection and associated inflammatory response by Qiao, Yuanyuan, Wotring, Jesse W, Zheng, Yang, Zhang, Charles J, Zhang, Yuping, Jiang, Xia, Pretto, Carla D, Eyunni, Sanjana, Parolia, Abhijit, He, Tongchen, Cheng, Caleb, Cao, Xuhong, Wang, Rui, Su, Fengyun, Ellison, Stephanie J, Wang, Yini, Qin, Jun, Yan, Honghua, Zhou, Qianxiang, Ma, Liandong, Sexton, Jonathan Z, Chinnaiyan, Arul M

“…Early in the COVID-19 pandemic, data suggested that males had a higher risk of developing severe disease and that androgen deprivation therapy might be…”
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Differential Pathogenesis of Respiratory Syncytial Virus Clinical Isolates in BALB/c Mice by STOKES, Kate L, CHI, Michael H, HOTARD, Anne, SHERRILL, Taylor P, STOKES PEEBLES, R, MOORE, Martin L, SAKAMOTO, Kaori, NEWCOMB, Dawn C, CURRIER, Michael G, HUCKABEE, Matthew M, SUJIN LEE, GOLENIEWSKA, Kasia, PRETTO, Carla, WILLIAMS, John V

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Matrix Metalloproteinase Activity in Infections by an Encephalitic Virus, Mouse Adenovirus Type 1 by Ashley, Shanna L, Pretto, Carla D, Stier, Matthew T, Kadiyala, Padma, Castro-Jorge, Luiza, Hsu, Tien-Huei, Doherty, Robert, Carnahan, Kelly E, Castro, Maria G, Lowenstein, Pedro R, Spindler, Katherine R

“…Mouse adenovirus type 1 (MAV-1) infection causes encephalitis in susceptible strains of mice and alters the permeability of infected brains to small molecules,…”
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Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR) by Goodman, Danielle E, Pretto, Carla D, Krepostman, Tomas A, Carnahan, Kelly E, Spindler, Katherine R

“…Protein kinase R (PKR) plays a major role in activating host immunity during infection by sensing double-stranded RNA (dsRNA) produced by viruses. Once…”
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A Protective Role for Interleukin-1 Signaling during Mouse Adenovirus Type 1-Induced Encephalitis by Castro-Jorge, Luiza A, Pretto, Carla D, Smith, Asa B, Foreman, Oded, Carnahan, Kelly E, Spindler, Katherine R

“…Interleukin-1β (IL-1β), an inflammatory cytokine and IL-1 receptor ligand, has diverse activities in the brain. We examined whether IL-1 signaling contributes…”
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Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier by Tirumuru, Nagaraja, Pretto, Carla D, Castro Jorge, Luiza A, Spindler, Katherine R

“…Mouse adenovirus type 1 (MAV-1) infects endothelial cells and disrupts the blood-brain barrier (BBB), causing encephalitis in inbred and outbred mice. Using a…”
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Relevance of Akt phosphorylation in cell transformation induced by Jaagsiekte sheep retrovirus by Zavala, Guillermo, Pretto, Carla, Chow, Yen-Hung J, Jones, LeeAnn, Alberti, Alberto, Grego, Elena, De las Heras, Marcelo, Palmarini, Massimo

“…Expression of the JSRV envelope (Env) is sufficient to transform immortalized rodent fibroblasts. A putative docking site for the PI3-K kinase (Y 590-X-X-M…”
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Transformation of Rodent Fibroblasts by the Jaagsiekte Sheep Retrovirus Envelope Is Receptor Independent and Does Not Require the Surface Domain by Chow, Yen-Hung J, Alberti, Alberto, Mura, Manuela, Pretto, Carla, Murcia, Pablo, Albritton, Lorraine M, Palmarini, Massimo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Surface translocation of ACE2 and TMPRSS2 upon TLR4/7/8 activation is required for SARS-CoV-2 infection in circulating monocytes by Yao, Yi, Subedi, Kalpana, Liu, Tingting, Khalasawi, Namir, Pretto-Kernahan, Carla Diana, Wotring, Jesse William, Wang, Jie, Yin, Congcong, Jiang, Aimin, Fu, Chunmei, Dimitrion, Peter, Li, Jia, Veenstra, Jesse, Yi, Qijun, McKinnon, Kathy, McKinnon, John Ernest, Sexton, Jonathan Zachary, Zhou, Li, Mi, Qing-Sheng

“…Infection of human peripheral blood cells by SARS-CoV-2 has been debated because immune cells lack mRNA expression of both angiotensin-converting enzyme 2…”
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Circulating Monocytes Co-expressing Surface ACE2 and TMPRSS2 upon TLR4/7/8 Activation Are Susceptible to SARS-CoV-2 Infection by Yao, Yi, Subedi, Kalpana, Sexton, Jonathan Z., Liu, Tingting, Khalasawi, Namir, Pretto, Carla, Wotring, Jesse W, Wang, Jie, Yin, Congcong, Jiang, Aimin, Li, Jia, Zhou, Li, McKinnon, John, Mi, Qing-Sheng

“…Abstract Angiotensin-converting enzyme 2 (ACE2) receptor is required for SARS-CoV-2 entry into human cells. However, emerging evidence shows SARS-CoV-2…”
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BALB/c mouse model of RSV clinical isolate A2001/2-20 pathogenesis (49.13) by Stokes, Kate, Chi, Michael, Sakamoto, Kaori, Newcomb, Dawn, Huckabee, Matthew, Lee, Sujin, Pretto, Carla, Williams, John, Peebles, R., Moore, Martin

“…Abstract Airway mucus is a hallmark of respiratory syncytial virus (RSV) lower respiratory tract illness. Laboratory RSV strains (A2, Long, and Line 19)…”
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Epidermal Growth Factor Receptor (EGFR) Mediates Cell Fusion and Infectivity Of Respiratory Syncytial Virus (RSV) by Lee, Sujin, Currier, Michael G, Hotard, Anne L, Meng, Jia, Pretto, Carla, Power, Ultan F, Villenave, Remi, Shields, Michael D, Chi, Michael H, Peebles, R. Stokes, Moore, Martin L

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