Search Results - "Pretti, Marco Antônio M"
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Poor clinical outcome in metastatic melanoma is associated with a microRNA-modulated immunosuppressive tumor microenvironment
Published in Journal of translational medicine (05-02-2020)“…Interaction between malignant cells and immune cells that reside within the tumor microenvironment (TME) modulate different aspects of tumor development and…”
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Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19
Published in Frontiers in immunology (16-12-2020)“…The world is dealing with one of the worst pandemics ever. SARS-CoV-2 is the etiological agent of COVID-19 that has already spread to more than 200 countries…”
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Dietary Protein Restriction Improves Metabolic Dysfunction in Patients with Metabolic Syndrome in a Randomized, Controlled Trial
Published in Nutrients (28-06-2022)“…Dietary restriction (DR) reduces adiposity and improves metabolism in patients with one or more symptoms of metabolic syndrome. Nonetheless, it remains elusive…”
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Distribution of a novel CYP2C haplotype in Native American populations
Published in Frontiers in genetics (21-03-2023)“…The gene, located in the cluster, encodes the major drug metabolism enzyme CYP2C19. This gene is highly polymorphic and no-function ( and * ), reduced function…”
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Single Nucleotide Variants as Proxies for HLA-A31:01 in Native American Populations
Published in Frontiers in pharmacology (14-04-2022)“…Carbamazepine triggers dermatologic hypersensitivity reactions, associated with specific human leukocyte antigens (HLAs), especially and Previous efforts to…”
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Functional plasticity shapes neutrophil response to Leishmania major infection in susceptible and resistant strains of mice
Published in PLoS pathogens (08-10-2024)“…Neutrophils rapidly infiltrate sites of infection and possess several microbicidal strategies, such as neutrophil extracellular traps release and phagocytosis…”
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In silico analysis of mutant epitopes in new SARS-CoV-2 lineages suggest global enhanced CD8+ T cell reactivity and also signs of immune response escape
Published in Infection, genetics and evolution (01-04-2022)“…SARS-CoV-2 variants of concern have emerged since the COVID-19 outburst, notably the lineages detected in the UK, South Africa, and Brazil. Their increased…”
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SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner
Published in Nature communications (29-09-2022)“…Visceral adiposity is a risk factor for severe COVID-19, and a link between adipose tissue infection and disease progression has been proposed. Here we…”
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Connecting multiple microenvironment proteomes uncovers the biology in head and neck cancer
Published in Nature communications (07-11-2022)“…The poor prognosis of head and neck cancer (HNC) is associated with metastasis within the lymph nodes (LNs). Herein, the proteome of 140 multisite samples from…”
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