Search Results - "Pretorius, Alri"

Editorial: Immune transcriptome sequencing reveals secrets of veterinary infectious diseases by van Kleef, Mirinda, Pretorius, Alri

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Genetic diversity of Ehrlichia ruminantium field strains from selected farms in South Africa by Steyn, Helena C, Pretorius, Alri

“…Heartwater is a tick-borne disease caused by the intracellular rickettsial parasite Ehrlichia ruminantium and transmitted by Amblyomma hebraeum ticks…”
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Th1 and Th2 epitopes of Cowdria polymorphic gene 1 of Ehrlichia ruminantium by Ngoepe, Tlou A, Pretorius, Alri, Steyn, Helena C, Van Kleef, Mirinda

“…Cowdria polymorphic gene 1 (cpg1, Erum2510, ERUM_RS01380) has been shown to induce 30% and 100% protection in sheep immunised by deoxyribonucleic acid (DNA)…”
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Characterisation of South African field Ehrlichia ruminantium using multilocus sequence typing by Dlamkile, Zinathi, Neves, Luis, Morar-Leather, Darshana, Brandt, Christopher, Pretorius, Alri, Steyn, Helena, Liebenberg, Junita

“…Abstract only…”
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The Development of Dual Vaccines against Lumpy Skin Disease (LSD) and Bovine Ephemeral Fever (BEF) by Douglass, Nicola, Omar, Ruzaiq, Munyanduki, Henry, Suzuki, Akiko, de Moor, Warren, Mutowembwa, Paidamwoyo, Pretorius, Alri, Nefefe, Tshifhiwa, Schalkwyk, Antoinette van, Kara, Pravesh, Heath, Livio, Williamson, Anna-Lise

“…Dual vaccines (n = 6) against both lumpy skin disease (LSD) and bovine ephemeral fever (BEF) were constructed, based on the BEFV glycoprotein (G) gene, with or…”
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B-cell epitopes of African horse sickness virus serotype 4 recognised by immune horse sera by Van Schalkwyk, Antoinette, Mathebula, Evans M., Fehrsen, Jeanni, Pretorius, Alri, Van Wyngaardt, Wouter, Faber, Frederika E.

“…Identifying antigenic proteins and mapping their epitopes is important for the development of diagnostic reagents and recombinant vaccines. B-cell epitopes of…”
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Cellular immune responses induced in vitro by Ehrlichia ruminantium secreted proteins and identification of vaccine candidate peptides by Thema, Nontobeko, Pretorius, Alri, Tshilwane, Selaelo I, Liebenberg, Junita, Steyn, Helena, Van Kleef, Mirinda

“…Secreted proteins are reported to induce cell-mediated immunity characterised by the production of interferon-gamma (IFN)-γ. In this study three open reading…”
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The Genome of the Heartwater Agent Ehrlichia ruminantium Contains Multiple Tandem Repeats of Actively Variable Copy Number by Collins, Nicola E., Liebenberg, Junita, de Villiers, Etienne P., Brayton, Kelly A., Louw, Elmarié, Pretorius, Alri, Faber, F. Erika, van Heerden, Henriette, Josemans, Antoinette, van Kleef, Mirinda, Steyn, Helena C., van Strijp, M. Fransie, Zweygarth, Erich, Jongejan, Frans, Maillard, Jean Charles, Berthier, David, Botha, Marli, Joubert, Fourie, Corton, Craig H., Thomson, Nicholas R., Allsopp, Maria T., Allsopp, Basil A., Beaty, Barry J.

“…Heartwater, a tick-borne disease of domestic and wild ruminants, is caused by the intracellular rickettsia Ehrlichia ruminantium (previously known as Cowdria…”
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The impact of Escherichia coli contamination products present in recombinant African horse sickness virus serotype 4 proteins on the innate and humoral immune responses by Faber, Erika, Tshilwane, Selaelo Ivy, Van Kleef, Mirinda, Pretorius, Alri

“…Transcriptome analysis was used to characterise the in vitro primary and secondary immune responses induced in horse peripheral blood mononuclear cells (PBMC)…”
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Apoptosis versus survival of African horse sickness virus serotype 4-infected horse peripheral blood mononuclear cells by Faber, Erika, Tshilwane, Selaelo Ivy, Van Kleef, Mirinda, Pretorius, Alri

“…•Apoptosis is a major host defense mechanism to limit viral replication.•Virulent (secondary response) and attenuated AHSV4-infected PBMC were killed.•Viral…”
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Genetic diversity of by Steyn, Helena C., Pretorius, Alri

“…Heartwater is a tick-borne disease caused by the intracellular rickettsial parasite Ehrlichia ruminantium and transmitted by Amblyomma hebraeum ticks…”
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Rift Valley Fever vaccine strategies: Enhanced stability of RVF Clone 13 by Moetlhoa, Boitumelo, Tjale, Mabotse, Pretorius, Alri, Hayeshi, Rose, Grobler, Anne, Mokoena, Nobalanda B.

“…Rift Valley Fever virus (RVFV) causes the zoonotic RVF disease, which results in substantial economic losses in livestock industries. Regular vaccination of…”
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Identification of T cell and linear B cell epitopes on African horse sickness virus serotype 4 proteins VP1-1, VP2, VP4, VP7 and NS3 by Faber, Erika, van Schalkwyk, Antoinette, Ivy Tshilwane, Selaelo, Van Kleef, Mirinda, Pretorius, Alri

“…•AHSV4 VP1, -2, -4, -7 and NS3 contain regions with CD8+ T cell epitopes.•Overlapping peptides spanning these AHSV4 proteins were synthesized.•Recall immune…”
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Virulent African horse sickness virus serotype 4 interferes with the innate immune response in horse peripheral blood mononuclear cells in vitro by Faber, Erika, Tshilwane, Selaelo Ivy, Kleef, Mirinda Van, Pretorius, Alri

“…African horse sickness (AHS) is caused by African horse sickness virus (AHSV), a double stranded RNA (dsRNA) virus of the genus Orbivirus, family Reoviridae…”
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Th1 and Th2 epitopes of polymorphic gene 1 of by Ngoepe, Tlou A., Pretorius, Alri, Steyn, Helena C., Van Kleef, Mirinda

“…Cowdria polymorphic gene 1 (cpg1, Erum2510, ERUM_RS01380) has been shown to induce 30% and 100% protection in sheep immunised by deoxyribonucleic acid (DNA)…”
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Characterisation of putative immunomodulatory gene knockouts of lumpy skin disease virus in cattle towards an improved vaccine by Kara, Pravesh D., Mather, Arshad S., Pretorius, Alri, Chetty, Thireshni, Babiuk, Shawn, Wallace, David B.

“…•The putative interleukin-10-like and interferon-gamma receptor-like gene deleted from the genome of a LSDV field isolate.•Severe post-vaccinal reactions…”
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Transcriptome analysis of Ehrlichia ruminantium in the ruminant host at the tick bite site and in the tick vector salivary glands by Tjale, Mabotse A., Liebenberg, Junita, Steyn, Helena, Van Kleef, Mirinda, Pretorius, Alri

“…Heartwater is a non-contagious tick-borne disease of domestic and wild ruminants. Data regarding the complex processes involved during pathogen-vector–host…”
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Safety and efficacy of an attenuated heartwater (Ehrlichia ruminantium) vaccine administered by the intramuscular route in cattle, sheep and Angora goats by Latif, Abdalla A., Steyn, Helena C., Josemans, Antoinette I., Marumo, Ratselane D., Pretorius, Alri, Christo Troskie, P., Combrink, Michael P., Molepo, Lefoka C., Haw, Anna, Mbizeni, Sikhumbuzo, Zweygarth, Erich, Mans, Ben J.

“…Heartwater is an economically important tick-borne disease of ruminants in Africa. The current commercial vaccine uses live Ehrlichia ruminantium from blood of…”
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Virus-specific CD8+ T-cells detected in PBMC from horses vaccinated against African horse sickness virus by Pretorius, Alri, Van Kleef, Mirinda, Van Wyngaardt, Wouter, Heath, Jeanette

“…African horsesickness (AHS) is an infectious but noncontagious viral disease affecting all species of Equidae. The recall immune response of AHSV naïve horses…”
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Transcriptomic analysis of Ehrlichia ruminantium during the developmental stages in bovine and tick cell culture by Tjale, Mabotse A., Pretorius, Alri, Josemans, Antoinette, Kleef, Mirinda Van, Liebenberg, Junita

“…The use of bioinformatics tools to search for possible vaccine candidates has been successful in recent years. In an attempt to search for additional vaccine…”
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