Search Results - "Prestes, Priscilla R"

Muscle-Enriched MicroRNAs Isolated from Whole Blood Are Regulated by Exercise and Are Potential Biomarkers of Cardiorespiratory Fitness by Denham, Joshua, Prestes, Priscilla R

“…MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally. Evidence indicating miRNAs influence…”
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A Guide to the Short, Long and Circular RNAs in Hypertension and Cardiovascular Disease by Prestes, Priscilla R, Maier, Michelle C, Woods, Bradley A, Charchar, Fadi J

“…Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in adults in developed countries. CVD encompasses many diseased states, including…”
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Molecular insights into genome-wide association studies of chronic kidney disease-defining traits by Xu, Xiaoguang, Eales, James M., Akbarov, Artur, Guo, Hui, Becker, Lorenz, Talavera, David, Ashraf, Fehzan, Nawaz, Jabran, Pramanik, Sanjeev, Bowes, John, Jiang, Xiao, Dormer, John, Denniff, Matthew, Antczak, Andrzej, Szulinska, Monika, Wise, Ingrid, Prestes, Priscilla R., Glyda, Maciej, Bogdanski, Pawel, Zukowska-Szczechowska, Ewa, Berzuini, Carlo, Woolf, Adrian S., Samani, Nilesh J., Charchar, Fadi J., Tomaszewski, Maciej

“…Genome-wide association studies (GWAS) have identified >100 loci of chronic kidney disease-defining traits (CKD-dt). Molecular mechanisms underlying these…”
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Plasma lipocalin-2/NGAL is stable over 12 weeks and is not modulated by exercise or dieting by Nakai, Michael E., Denham, Joshua, Prestes, Priscilla R., Eikelis, Nina, Lambert, Elisabeth A., Straznicky, Nora E., Schlaich, Markus P., Esler, Murray D., O’Brien, Brendan J., Charchar, Fadi J., Lambert, Gavin W., Marques, Francine Z.

“…Amongst other immune cells, neutrophils play a key role in systemic inflammation leading to cardiovascular disease and can release inflammatory factors,…”
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Increased expression of telomere-regulating genes in endurance athletes with long leukocyte telomeres by Denham, Joshua, O'Brien, Brendan J, Prestes, Priscilla R, Brown, Nicholas J, Charchar, Fadi J

“…Leukocyte telomeres shorten with age, and excessive shortening is associated with age-related cardiometabolic diseases. Exercise training may prevent disease…”
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Predicting biogeographical ancestry in admixed individuals - values and limitations of using uniparental and autosomal markers by Prestes, Priscilla R., Mitchell, R. John, Daniel, Runa, Sanchez, Juan J., van Oorschot, Roland A.H.

“…When microsatellite profiles generated from crime scene samples do not match a known person, or eye-witness information is unreliable, highly informative…”
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Four-week inhibition of the renin-angiotensin system in spontaneously hypertensive rats results in persistently lower blood pressure with reduced kidney renin and changes in expression of relevant gene networks by Byars, Sean G, Prestes, Priscilla R, Suphapimol, Varaporn, Takeuchi, Fumihiko, De Vries, Nathan, Maier, Michelle C, Melo, Mariana, Balding, David, Samani, Nilesh, Allen, Andrew M, Kato, Norihiro, Wilkinson-Berka, Jennifer L, Charchar, Fadi, Harrap, Stephen B

“…Prevention of human hypertension is an important challenge and has been achieved in experimental models. Brief treatment with renin-angiotensin system (RAS)…”
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DNA copy number variations – Do these big mutations have a big effect on cardiovascular risk? by Prestes, Priscilla R., Maier, Michelle C., Charchar, Fadi J.

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Human Y Chromosome Exerts Pleiotropic Effects on Susceptibility to Atherosclerosis by Eales, James M, Maan, Akhlaq A, Xu, Xiaoguang, Michoel, Tom, Hallast, Pille, Batini, Chiara, Zadik, Daniel, Prestes, Priscilla R, Molina, Elsa, Denniff, Matthew, Schroeder, Juliane, Bjorkegren, Johan L.M, Thompson, John, Maffia, Pasquale, Guzik, Tomasz J, Keavney, Bernard, Jobling, Mark A, Samani, Nilesh J, Charchar, Fadi J, Tomaszewski, Maciej

“…OBJECTIVE:The male-specific region of the Y chromosome (MSY) remains one of the most unexplored regions of the genome. We sought to examine how the genetic…”
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Tripartite motif-containing 55 identified as functional candidate for spontaneous cardiac hypertrophy in the rat locus cardiac mass 22 by Prestes, Priscilla R, Marques, Francine Z, Lopez-Campos, Guillermo, Booth, Scott A, McGlynn, Maree, Lewandowski, Paul, Delbridge, Lea M.D, Harrap, Stephen B, Charchar, Fadi J

“…BACKGROUND:Left ventricular (LV) hypertrophy is a risk factor for cardiovascular death, but the genetic factors determining LV size and predisposition to…”
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Telomere dynamics during aging in polygenic left ventricular hypertrophy by Marques, Francine Z, Booth, Scott A, Prestes, Priscilla R, Curl, Claire L, Delbridge, Lea M D, Lewandowski, Paul, Harrap, Stephen B, Charchar, Fadi J

“…Short telomeres are associated with increased risk of cardiovascular disease. Here we studied cardiomyocyte telomere length at key ages during the ontogeny of…”
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Measurement of absolute copy number variation reveals association with essential hypertension by Marques, Francine Z, Prestes, Priscilla R, Pinheiro, Leonardo B, Scurrah, Katrina, Emslie, Kerry R, Tomaszewski, Maciej, Harrap, Stephen B, Charchar, Fadi J

“…The role of copy number variation (CNV) has been poorly explored in essential hypertension in part due to technical difficulties in accurately assessing…”
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Best practice data life cycle approaches for the life sciences [version 1; peer review: 2 approved with reservations] by Griffin, Philippa C, Khadake, Jyoti, LeMay, Kate S, Lewis, Suzanna E, Orchard, Sandra, Pask, Andrew, Pope, Bernard, Roessner, Ute, Russell, Keith, Seemann, Torsten, Treloar, Andrew, Tyagi, Sonika, Christiansen, Jeffrey H, Dayalan, Saravanan, Gladman, Simon, Hangartner, Sandra B, Hayden, Helen L, Ho, William W.H, Keeble-Gagnère, Gabriel, Korhonen, Pasi K, Neish, Peter, Prestes, Priscilla R, Richardson, Mark F, Watson-Haigh, Nathan S, Wyres, Kelly L, Young, Neil D, Schneider, Maria Victoria

“…Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advances in instrumentation for data…”
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PT349 Droplet digital PCR measurement of copy number variation in genome-wide association regions for blood pressure reveal association with essential hypertension by Marques, Francine, Prestes, Priscilla R, Pinheiro, Leonardo B, Scurrah, Katrina, Emslie, Kerry R, Tomaszewski, Maciej, Harrap, Stephen B, Charchar, Fadi J

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Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension by Charchar, Fadi J, Prestes, Priscilla R, Mills, Charlotte, Ching, Siew Mooi, Neupane, Dinesh, Marques, Francine Z, Sharman, James E, Vogt, Liffert, Burrell, Louise M, Korostovtseva, Lyudmila, Zec, Manja, Patil, Mansi, Schultz, Martin G, Wallen, Matthew P, Renna, Nicolás F, Islam, Sheikh Mohammed Shariful, Hiremath, Swapnil, Gyeltshen, Tshewang, Chia, Yook-Chin, Gupta, Abhinav, Schutte, Aletta E, Klein, Britt, Borghi, Claudio, Browning, Colette J, Czesnikiewicz-Guzik, Marta, Lee, Hae-Young, Itoh, Hiroshi, Miura, Katsuyuki, Brunström, Mattias, Campbell, Norm R C, Akinnibossun, Olutope Arinola, Veerabhadrappa, Praveen, Wainford, Richard D, Kruger, Ruan, Thomas, Shane A, Komori, Takahiro, Ralapanawa, Udaya, Cornelissen, Véronique A, Kapil, Vikas, Li, Yan, Zhang, Yuqing, Jafar, Tazeen H, Khan, Nadia, Williams, Bryan, Stergiou, George, Tomaszewski, Maciej

“…Hypertension, defined as persistently elevated systolic blood pressure (SBP) >140 mmHg and/or diastolic blood pressure (DBP) at least 90 mmHg (International…”
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Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney by Eales, James M., Jiang, Xiao, Xu, Xiaoguang, Saluja, Sushant, Akbarov, Artur, Cano-Gamez, Eddie, McNulty, Michelle T., Finan, Christopher, Guo, Hui, Wystrychowski, Wojciech, Szulinska, Monika, Thomas, Huw B., Pramanik, Sanjeev, Chopade, Sandesh, Prestes, Priscilla R., Wise, Ingrid, Evangelou, Evangelos, Salehi, Mahan, Shakanti, Yusif, Ekholm, Mikael, Denniff, Matthew, Nazgiewicz, Alicja, Eichinger, Felix, Godfrey, Bradley, Antczak, Andrzej, Glyda, Maciej, Król, Robert, Eyre, Stephen, Brown, Jason, Berzuini, Carlo, Bowes, John, Caulfield, Mark, Zukowska-Szczechowska, Ewa, Zywiec, Joanna, Bogdanski, Pawel, Kretzler, Matthias, Woolf, Adrian S., Talavera, David, Keavney, Bernard, Maffia, Pasquale, Guzik, Tomasz J., O’Keefe, Raymond T., Trynka, Gosia, Samani, Nilesh J., Hingorani, Aroon, Sampson, Matthew G., Morris, Andrew P., Charchar, Fadi J., Tomaszewski, Maciej

“…The kidney is an organ of key relevance to blood pressure (BP) regulation, hypertension and antihypertensive treatment. However, genetically mediated renal…”
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Genetic imputation of kidney transcriptome, proteome and multi-omics illuminates new blood pressure and hypertension targets by Xu, Xiaoguang, Khunsriraksakul, Chachrit, Eales, James M., Rubin, Sebastien, Scannali, David, Saluja, Sushant, Talavera, David, Markus, Havell, Wang, Lida, Drzal, Maciej, Maan, Akhlaq, Lay, Abigail C., Prestes, Priscilla R., Regan, Jeniece, Diwadkar, Avantika R., Denniff, Matthew, Rempega, Grzegorz, Ryszawy, Jakub, Król, Robert, Dormer, John P., Szulinska, Monika, Walczak, Marta, Antczak, Andrzej, Matías-García, Pamela R., Waldenberger, Melanie, Woolf, Adrian S., Keavney, Bernard, Zukowska-Szczechowska, Ewa, Wystrychowski, Wojciech, Zywiec, Joanna, Bogdanski, Pawel, Danser, A. H. Jan, Samani, Nilesh J., Guzik, Tomasz J., Morris, Andrew P., Liu, Dajiang J., Charchar, Fadi J., Tomaszewski, Maciej

“…Genetic mechanisms of blood pressure (BP) regulation remain poorly defined. Using kidney-specific epigenomic annotations and 3D genome information we generated…”
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Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure by Marques, Francine Z, Prestes, Priscilla R, Byars, Sean G, Ritchie, Scott C, Würtz, Peter, Patel, Sheila K, Booth, Scott A, Rana, Indrajeetsinh, Minoda, Yosuke, Berzins, Stuart P, Curl, Claire L, Bell, James R, Wai, Bryan, Srivastava, Piyush M, Kangas, Antti J, Soininen, Pasi, Ruohonen, Saku, Kähönen, Mika, Lehtimäki, Terho, Raitoharju, Emma, Havulinna, Aki, Perola, Markus, Raitakari, Olli, Salomaa, Veikko, Ala-Korpela, Mika, Kettunen, Johannes, McGlynn, Maree, Kelly, Jason, Wlodek, Mary E, Lewandowski, Paul A, Delbridge, Lea M, Burrell, Louise M, Inouye, Michael, Harrap, Stephen B, Charchar, Fadi J

“…Cardiac hypertrophy increases the risk of developing heart failure and cardiovascular death. The neutrophil inflammatory protein, lipocalin-2 (LCN2/NGAL), is…”
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Best practice data life cycle approaches for the life sciences [version 2; peer review: 2 approved] by Griffin, Philippa C, Khadake, Jyoti, LeMay, Kate S, Lewis, Suzanna E, Orchard, Sandra, Pask, Andrew, Pope, Bernard, Roessner, Ute, Russell, Keith, Seemann, Torsten, Treloar, Andrew, Tyagi, Sonika, Christiansen, Jeffrey H, Dayalan, Saravanan, Gladman, Simon, Hangartner, Sandra B, Hayden, Helen L, Ho, William W.H, Keeble-Gagnère, Gabriel, Korhonen, Pasi K, Neish, Peter, Prestes, Priscilla R, Richardson, Mark F, Watson-Haigh, Nathan S, Wyres, Kelly L, Young, Neil D, Schneider, Maria Victoria

“…Throughout history, the life sciences have been revolutionised by technological advances; in our era this is manifested by advances in instrumentation for data…”
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Abstract 20716: Can Long-Term Endurance Exercise Change MicroRNA Profiles and Prevent Cardiovascular Disease? by Prestes, Priscilla R, O’Brien, Brendan J, Charchar, Fadi J

“…IntroductionExercise improves cardiovascular fitness and reduces the incidence of cardiovascular disease (CVD). MicroRNAs (miR) are small non-coding RNA…”
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