Search Results - "Pressman, Sigal"

Silencing by small RNAs is linked to endosomal trafficking by Kim, Kevin, Lee, Young Sik, Carthew, Richard W, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Andress, Arlise P, Preall, Jonathan B, Bellare, Priya, Pressman, Sigal, White, Jamie L, Li, Xin, Cassidy, Justin J, Lubell, Kim, Sontheimer, Erik J

“…Small RNAs direct RNA-induced silencing complexes (RISCs) to regulate stability and translation of mRNAs. RISCs associated with target mRNAs often accumulate…”
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Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs by Church, Victoria A., Pressman, Sigal, Isaji, Mamiko, Truscott, Mary, Cizmecioglu, Nihal Terzi, Buratowski, Stephen, Frolov, Maxim V., Carthew, Richard W.

“…The cellular abundance of mature microRNAs (miRNAs) is dictated by the efficiency of nuclear processing of primary miRNA transcripts (pri-miRNAs) into…”
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RNA-binding protein conserved in both microtubule- and microfilament-based RNA localization by Havin, L, Git, A, Elisha, Z, Oberman, F, Yaniv, K, Schwartz, S P, Standart, N, Yisraeli, J K

“…Vg1 mRNA translocation to the vegetal cortex of Xenopus oocytes requires intact microtubules, and a 3' UTR cis-acting element (termed VLE), which also mediates…”
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Infliximab–Tumor Necrosis Factor Complexes Elicit Formation of Anti-Drug Antibodies by Bar-Yoseph, Haggai, Pressman, Sigal, Blatt, Alexandra, Gerassy Vainberg, Shiran, Maimon, Naama, Starosvetsky, Elina, Ungar, Bella, Ben-Horin, Shomron, Shen-Orr, Shai S., Chowers, Yehuda

“…Some patients develop anti-drug antibodies (ADAs), which reduce the efficacy of infliximab, a monoclonal antibody against tumor necrosis factor (TNF), in the…”
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Antibiotic use differentially affects the risk of anti-drug antibody formation during anti-TNFα therapy in inflammatory bowel disease patients: a report from the epi-IIRN by Gorelik, Yuri, Freilich, Shay, Gerassy-Vainberg, Shiran, Pressman, Sigal, Friss, Chagit, Blatt, Alexandera, Focht, Gili, Weisband, Yiska Loewenberg, Greenfeld, Shira, Kariv, Revital, Lederman, Nathan, Dotan, Iris, Geva-Zatorsky, Naama, Shen-Orr, Shai Shlomo, Kashi, Yechezkel, Chowers, Yehuda

“…Anti-drug antibodies (ADA) to anti-tumour necrosis factor (anti-TNF) therapy drive treatment loss of response. An association between intestinal microbial…”
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Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota by Carasso, Shaqed, Zaatry, Rawan, Hajjo, Haitham, Kadosh-Kariti, Dana, Ben-Assa, Nadav, Naddaf, Rawi, Mandelbaum, Noa, Pressman, Sigal, Chowers, Yehuda, Gefen, Tal, Jeffrey, Kate L, Jofre, Juan, Coyne, Michael J, Comstock, Laurie E, Sharon, Itai, Geva-Zatorsky, Naama

“…Reversible genomic DNA inversions control the expression of numerous gut bacterial molecules, but how this impacts disease remains uncertain. By analyzing…”
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Anti-infliximab Antibodies with Neutralizing Capacity in Patients with Inflammatory Bowel Disease: Distinct Clinical Implications Revealed by a Novel Assay by Weisshof, Roni, Ungar, Bella, Blatt, Alexandra, Dahan, Aviva, Pressman, Sigal, Waterman, Matti, Kopylov, Uri, Ben-Horin, Shomron, Chowers, Yehuda

“…About 60% of infliximab (IFX)-treated patients develop antidrug antibodies (ADA), although their clinical significance remains disputed. The aim of this study…”
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Differential Serum-intestinal Dynamics of Infliximab and Adalimumab in Inflammatory Bowel Disease Patients by Bar-Yoseph, Haggai, Blatt, Alexandra, Gerassy, Shiran, Pressman, Sigal, Mousa, Amjad, Sabo, Edmond, Waterman, Matti, Ungar, Bella, Ben-Horin, Shomron, Chowers, Yehuda

“…Abstract Background and Aims Therapeutic drug monitoring is used to guide anti-tumour necrosis factor [TNF] therapy. However, the associations between serum…”
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A personalized network framework reveals predictive axis of anti-TNF response across diseases by Gerassy-Vainberg, Shiran, Starosvetsky, Elina, Gaujoux, Renaud, Blatt, Alexandra, Maimon, Naama, Gorelik, Yuri, Pressman, Sigal, Alpert, Ayelet, Bar-Yoseph, Haggai, Dubovik, Tania, Perets, Benny, Katz, Adir, Milman, Neta, Segev, Meital, Chowers, Yehuda, Shen-Orr, Shai S

“…Personalized treatment of complex diseases has been mostly predicated on biomarker identification of one drug-disease combination at a time. Here, we use a…”
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The Role of MHC Class I Glycoproteins in the Regulation of Induction of Cell Death in Immunocytes by Malignant Melanoma Cells by Fishman, Daniel, Irena, Brodyanski, Kellman-Pressman, Sigal, Karas, Michael, Segal, Shraga

“…A deranged expression of MHC class I glycoproteins, characteristic of a variety of malignancies, contributes to the ability of cancer to avoid destruction by T…”
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Posttranscriptional gene silencing by Pressman, Sigal, Bei, Yanxia, Carthew, Richard

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SnapShot: Posttranscriptional Gene Silencing by Pressman, Sigal, Bei, Yanxia, Carthew, Richard

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SnapShot: Small RNA-Mediated Epigenetic Modifications by Bei, Yanxia, Pressman, Sigal, Carthew, Richard

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A Systematic Genetic Screen to Dissect the MicroRNA Pathway in Drosophila by Pressman, Sigal, Reinke, Catherine A, Wang, Xiaohong, Carthew, Richard W

“…A central goal of microRNA biology is to elucidate the genetic program of miRNA function and regulation. However, relatively few of the effectors that execute…”
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Erratum: Silencing by small RNAs is linked to endosomal trafficking by Lee, Young Sik, Pressman, Sigal, Andress, Arlise P., Kim, Kevin, White, Jamie L., Cassidy, Justin J., Li, Xin, Lubell, Kim, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Preall, Jonathan B., Bellare, Priya, Sontheimer, Erik J., Carthew, Richard W.

“…Nature Cell Biol. 11, 1150–1156 (2009); published online 16 August 2009; corrected after print, 11 November 2009 In both in the HTML and PDF versions of this…”
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Silencing by small RNAs is linked to endosome trafficking by Lee, Young Sik, Pressman, Sigal, Andress, Arlise P., Kim, Kevin, White, Jamie L., Cassidy, Justin J., Li, Xin, Lubell, Kim, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Preall, Jonathan B., Bellare, Priya, Sontheimer, Erik J., Carthew, Richard W.

“…Small RNAs direct RNA induced silencing complexes (RISCs) to regulate the stability and translation of mRNAs 1 , 2 . RISCs associated with target mRNAs often…”
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Silencing by small RNAs is linked to endosomal trafficking by Lee, Young Sik, Pressman, Sigal, Andress, Arlise P, Kim, Kevin, White, Jamie L, Cassidy, Justin J, Li, Xin, Lubell, Kim, Lim, Do Hwan, Cho, Ik Sang, Nakahara, Kenji, Preall, Jonathan B, Bellare, Priya, Sontheimer, Erik J, Carthew, Richard W

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Reconstitution of expression of H-2K region-encoded murine MHC class I glycoproteins in MHC class I-deficient B16BL6 melanoma cells affects the expression and function of antigen-processing machinery by Tsory, Sylvia, Kellman-Pressman, Sigal, Fishman, Daniel, Segal, Shraga

“…We have recently reported that reconstitution of expression of major histocompatibility complex (MHC) class I glycoproteins in MHC-deficient and highly…”
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Alterations in the Expression of MHC Class I Glycoproteins by B16BL6 Melanoma Cells Modulate Insulin Receptor-Regulated Signal Transduction and Augments Resistance to Apoptosis by Assa-Kunik, Efrat, Fishman, Daniel, Kellman-Pressman, Sigal, Tsory, Sylvia, Elhyany, Shira, Baharir, Ofer, Segal, Shraga

“…Abstract In a variety of malignancies, the immune-escape phenotype is associated, in part, with the inability of tumor cells to properly present their Ags to…”
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Alterations in the expression of MHC class I glycoproteins by B16BL6 melanoma cells modulate insulin receptor-regulated signal transduction and augment [correction of augments] resistance to apoptosis by Assa-Kunik, Efrat, Fishman, Daniel, Kellman-Pressman, Sigal, Tsory, Sylvia, Elhyany, Shira, Baharir, Ofer, Segal, Shraga

“…In a variety of malignancies, the immune-escape phenotype is associated, in part, with the inability of tumor cells to properly present their Ags to CTLs due…”
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