Search Results - "Pressly, Michelle A."

Exploring the Knowledge Gaps in Infant Drug Exposure From Human Milk: A Clinical Pharmacology Perspective by Guinn, Daphne, Pressly, Michelle A., Liu, Zhichao, Ceresa, Carrie, Samuels, Sherbet, Wang, Yow‐Ming, Madabushi, Rajanikanth, Schmidt, Stephan, Fletcher, Elimika Pfuma

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The quest for balance between capturing data and model complexity: A quantitative clinical pharmacology approach applied to monoclonal antibodies by Pressly, Michelle A., Peletier, Lambertus A., Zheng, Songmao, Sharma, Vishnu D., Lien, Yi Ting (Kayla), Wang, Weirong, Zhou, Honghui, Schmidt, Stephan

“…The main objective of this tutorial is to provide the readers with a roadmap of how to establish increasingly complex target‐mediated drug disposition (TMDD)…”
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Informing a Comprehensive Risk Assessment of Infant Drug Exposure From Human Milk: Application of a Physiologically Based Pharmacokinetic Lactation Model for Sotalol by Pressly, Michelle A., Schmidt, Stephan, Guinn, Daphne, Liu, Zhichao, Ceresa, Carrie, Samuels, Sherbet, Madabushi, Rajanikanth, Florian, Jeffry, Fletcher, Elimika Pfuma

“…Characterization of infant drug exposure through human milk is important and underexplored. Because infant plasma concentrations are not frequently collected…”
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Improvements and limitations in developing multivariate models of hemorrhage and transfusion risk for the obstetric population by Pressly, Michelle A., Parker, Robert S., Waters, Jonathan H., Beck, Stacy L., Jeyabalan, Arundhathi, Clermont, Gilles

“…Background Maternal hemorrhage protocols involve risk screening. These protocols prepare clinicians for potential hemorrhage and transfusion in individual…”
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Accelerating availability of clinically-relevant parameter estimates from thromboelastogram point-of-care device by Pressly, Michelle A., Parker, Robert S., Neal, Matthew D., Sperry, Jason L., Clermont, Gilles

“…Modeling approaches offer a novel way to detect and predict coagulopathy in trauma patients. A dynamic model, built and tested on thromboelastogram (TEG) data,…”
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Dynamic Modeling of Coagulation Advances the Bloody Fight to Improve Patient Outcomes by Pressly, Michelle A

“…Treating hospitalized patients with coagulation problems can prove complex. In trauma or obstetrics, complex coagulation events present a unique challenge to…”
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