Search Results - "Prens, Errol"

Pathophysiology of hidradenitis suppurativa: An update by Prens, Errol, MD, PhD, Deckers, Inge, MD

“…The pathogenesis of hidradenitis suppurativa (HS) or acne inversa is not completely understood. Recent research has led to greater insight into the mechanisms…”
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Two Phase 3 Trials of Adalimumab for Hidradenitis Suppurativa by Kimball, Alexa B, Okun, Martin M, Williams, David A, Gottlieb, Alice B, Papp, Kim A, Zouboulis, Christos C, Armstrong, April W, Kerdel, Francisco, Gold, Michael H, Forman, Seth B, Korman, Neil J, Giamarellos-Bourboulis, Evangelos J, Crowley, Jeffrey J, Lynde, Charles, Reguiai, Ziad, Prens, Errol-Prospero, Alwawi, Eihab, Mostafa, Nael M, Pinsky, Brett, Sundaram, Murali, Gu, Yihua, Carlson, Dawn M, Jemec, Gregor B.E

“…Hidradenitis suppurativa is a painful, chronic inflammatory skin disease. In two double-blind, placebo-controlled trials, treatment with adalimumab resulted in…”
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Hidradenitis suppurativa by Sabat, Robert, Jemec, Gregor B. E., Matusiak, Łukasz, Kimball, Alexa B., Prens, Errol, Wolk, Kerstin

“…Hidradenitis suppurativa (HS; also designated as acne inversa) is a chronic inflammatory disorder, which affects the intertriginous skin and is associated with…”
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Hidradenitis Suppurativa: A Systematic Review Integrating Inflammatory Pathways Into a Cohesive Pathogenic Model by Vossen, Allard R J V, van der Zee, Hessel H, Prens, Errol P

“…The pathogenesis of hidradenitis suppurativa (HS) is not fully understood. This systematic review examined the latest evidence for molecular inflammatory…”
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Hidradenitis Suppurativa/Acne Inversa: Criteria for Diagnosis, Severity Assessment, Classification and Disease Evaluation by Zouboulis, Christos C, Del Marmol, Veronique, Mrowietz, Ulrich, Prens, Errol P, Tzellos, Thrasivoulos, Jemec, Gregor B E

“…Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating disease, which inflicts a significant burden on patients and is…”
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Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies by Patrick, Matthew T., Zhang, Haihan, Wasikowski, Rachael, Prens, Errol P., Weidinger, Stephan, Gudjonsson, Johann E., Elder, James T., He, Kevin, Tsoi, Lam C.

“…Coronavirus disease 2019 (COVID-19) is commonly associated with skin manifestations, and may also exacerbate existing skin diseases, yet the relationship…”
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Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis by van der Fits, Leslie, Mourits, Sabine, Voerman, Jane S. A, Kant, Marius, Boon, Louis, Laman, Jon D, Cornelissen, Ferry, Mus, Anne-Marie, Florencia, Edwin, Prens, Errol P, Lubberts, Erik

“…Topical application of imiquimod (IMQ), a TLR7/8 ligand and potent immune activator, can induce and exacerbate psoriasis, a chronic inflammatory skin disorder…”
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Hidradenitis suppurativa: A retrospective study of 846 Dutch patients to identify factors associated with disease severity by Schrader, Anne M.R., MD, Deckers, Inge E., MD, van der Zee, Hessel H., MD, PhD, Boer, Jurr, MD, PhD, Prens, Errol P., MD, PhD

“…Background Few comprehensive studies exist on the epidemiology of hidradenitis suppurativa, a very distressing skin disease. Objective We sought to identify…”
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Insights into hidradenitis suppurativa by van Straalen, Kelsey R., Prens, Errol P., Gudjonsson, Johann E.

“…Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory skin disorder with a prevalence of around 1% and a profound impact on patients' quality…”
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Efficacy and Safety of Adalimumab in Conjunction With Surgery in Moderate to Severe Hidradenitis Suppurativa: The SHARPS Randomized Clinical Trial by Bechara, Falk G, Podda, Maurizio, Prens, Errol P, Horváth, Barbara, Giamarellos-Bourboulis, Evangelos J, Alavi, Afsaneh, Szepietowski, Jacek C, Kirby, Joslyn, Geng, Ziqian, Jean, Christine, Jemec, Gregor B E, Zouboulis, Christos C

“…Surgery is a mainstay in the management of hidradenitis suppurativa (HS). Adalimumab is the first drug approved for HS. To investigate the efficacy and safety…”
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Long-term adalimumab efficacy in patients with moderate-to-severe hidradenitis suppurativa/acne inversa: 3-year results of a phase 3 open-label extension study by Zouboulis, Christos C., Okun, Martin M., Prens, Errol P., Gniadecki, Robert, Foley, Peter A., Lynde, Charles, Weisman, Jamie, Gu, Yihua, Williams, David A., Jemec, Gregor B.E.

“…The optimal long-term dosing strategy for adalimumab (ADA) in hidradenitis suppurativa/acne inversa (HS) was evaluated by pooling the results of the PIONEER…”
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Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project by Garg, Amit, Neuren, Erica, Cha, Denny, Kirby, Joslyn S., Ingram, John R., Jemec, Gregor B.E., Esmann, Solveig, Thorlacius, Linnea, Villumsen, Bente, Marmol, Véronique del, Nassif, Aude, Delage, Maia, Tzellos, Thrasyvoulos, Moseng, Dagfinn, Grimstad, Øystein, Naik, Haley, Micheletti, Robert, Guilbault, Sandra, Miller, Angie Parks, Hamzavi, Iltefat, van der Zee, Hessel, Prens, Errol, Kappe, Naomi, Ardon, Christine, Kirby, Brian, Hughes, Rosalind, Zouboulis, Christos C., Nikolakis, Georgios, Bechara, Falk G., Matusiak, Lukasz, Szepietowski, Jacek, Glowaczewska, Amelia, Smith, Saxon D., Goldfarb, Noah, Daveluy, Steven, Avgoustou, Christina, Giamarellos-Bourboulis, Evangelos, Cohen, Steven, Soliman, Yssra, Brant, Elena Gonzalez, Akilov, Oleg, Sayed, Christopher, Tan, Jerry, Alavi, Afsaneh, Lowes, Michelle A., Pascual, José Carlos, Riad, Hassan, Fisher, Shani, Cohen, Arnon, Paek, So Yeon, Resnik, Barry, Ju, Qiang, Wang, Lanqi, Strunk, Andrew

“…A needs assessment for patients with hidradenitis suppurativa (HS) will support advancements in multidisciplinary care, treatment, research, advocacy, and…”
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Deroofing: A tissue-saving surgical technique for the treatment of mild to moderate hidradenitis suppurativa lesions by van der Zee, Hessel H., MD, Prens, Errol P., MD, PhD, Boer, Jurr, MD, PhD

“…Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease, often refractory to treatment. Patients with HS and dermatologists are in need…”
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Inflammatory bowel disease is associated with hidradenitis suppurativa: Results from a multicenter cross-sectional study by Deckers, Inge E., MD, PhD, Benhadou, Farida, MD, Koldijk, Marjolein J., MD, del Marmol, Veronique, MD, PhD, Horváth, Barbara, MD, PhD, Boer, Jurr, MD, PhD, van der Zee, Hessel H., MD, PhD, Prens, Errol P., MD, PhD

“…Background Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the…”
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Contribution of Genetics to the Susceptibility to Hidradenitis Suppurativa in a Large, Cross-sectional Dutch Twin Cohort by van Straalen, Kelsey R, Prens, Errol P, Willemsen, Gonneke, Boomsma, Dorret I, van der Zee, H H

“…Hidradenitis suppurativa is a chronic, inflammatory skin disease in which genetic factors are considered to play a role, with up to 38% of patients reporting a…”
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Complement Activation in Inflammatory Skin Diseases by Giang, Jenny, Seelen, Marc A J, van Doorn, Martijn B A, Rissmann, Robert, Prens, Errol P, Damman, Jeffrey

“…The complement system is a fundamental part of the innate immune system, playing a crucial role in host defense against various pathogens, such as bacteria,…”
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Apremilast for moderate hidradenitis suppurativa: Results of a randomized controlled trial by Vossen, Allard R.J.V., van Doorn, Martijn B.A., van der Zee, Hessel H., Prens, Errol P.

“…Effective anti-inflammatory treatments for hidradenitis suppurativa (HS) are limited. To evaluate the efficacy and short-term safety of apremilast in patients…”
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Correlation of early-onset hidradenitis suppurativa with stronger genetic susceptibility and more widespread involvement by Deckers, Inge E., MD, van der Zee, Hessel H., MD, PhD, Boer, Jurr, MD, PhD, Prens, Errol P., MD, PhD

“…Background The reported mean age of onset of hidradenitis suppurativa (HS) is between 20 and 24 years. Prepubertal onset is thought to be rare. Objective We…”
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Menses and pregnancy affect symptoms in hidradenitis suppurativa: A cross-sectional study by Vossen, Allard R.J.V., MD, van Straalen, Kelsey R., MD, Prens, Errol P., MD, PhD, van der Zee, Hessel H., MD, PhD

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New insights in hidradenitis suppurativa from a population‐based Dutch cohort: prevalence, smoking behaviour, socioeconomic status and comorbidities by Prens, Lisette M., Bouwman, Klasiena, Troelstra, Lisa D., Prens, Errol P., Alizadeh, Behrooz Z., Horváth, Barbara

“…Summary Background Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin condition and is associated with several comorbidities. Previous studies…”
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