Search Results - "Prenderville, Jack A"
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Revisiting Metchnikoff: Age-related Alterations in Microbiota-Gut-Brain Axis in the Mouse
Published in Brain, behavior, and immunity (01-10-2017)“…Highlights • The behaviour and physiology of young and aged mice were compared, with an emphasis on gut microbiota, gut permeability and markers of peripheral…”
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The role of cannabinoids in adult neurogenesis
Published in British journal of pharmacology (01-08-2015)“…The processes underpinning post‐developmental neurogenesis in the mammalian brain continue to be defined. Such processes involve the proliferation of neural…”
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The Antidepressant-Like Effects of a Clinically Relevant Dose of Ketamine Are Accompanied by Biphasic Alterations in Working Memory in the Wistar Kyoto Rat Model of Depression
Published in Frontiers in psychiatry (20-01-2021)“…Major depressive disorder (MDD) is the leading cause of disability worldwide. The majority of antidepressant drugs require several weeks or months of treatment…”
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Toll-like receptor signalling as a cannabinoid target
Published in Biochemical pharmacology (01-04-2024)“…[Display omitted] Toll-like receptors (TLRs) have become a focus in biomedicine and biomedical research given the roles of this unique family of innate immune…”
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Adding fuel to the fire: the impact of stress on the ageing brain
Published in Trends in neurosciences (Regular ed.) (01-01-2015)“…Highlights • Chronic stress and ageing have a similar impact on the brain at the behavioural and molecular level. • During ageing, chronic stress may have…”
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Tau and Amyloid β Protein in Patient-Derived Aqueous Brain Extracts Act Concomitantly to Disrupt Long-Term Potentiation in Vivo
Published in The Journal of neuroscience (09-08-2023)“…Amyloid β protein (Aβ) and tau, the two main proteins implicated in causing Alzheimer's disease (AD), are posited to trigger synaptic dysfunction long before…”
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Aging and the microbiota‐gut‐brain axis: Increased gut permeability, altered gut microbiota composition and increased peripheral inflammation are associated with neurobehavioural effects in aged mice
Published in The FASEB journal (01-04-2016)“…Abstract only Aging is associated with a number of adverse symptoms related to physical and mental decline, including altered immune function, cognitive…”
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