Search Results - "Prendergast, M"
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Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors
Published in Cell stem cell (01-10-2015)“…Infections are associated with extensive platelet consumption, representing a high risk for health. However, the mechanism coordinating the rapid regeneration…”
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Silver nanoparticles in the environment: Sources, detection and ecotoxicology
Published in The Science of the total environment (01-01-2017)“…The environmental impact of silver nanoparticles (AgNP) has become a topic of interest recently, this is due to the fact that AgNPs have been included in…”
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Transition Metal Mediated C–H Activation of 2‐Pyrones, 2‐Pyridones, 2‐Coumarins and 2‐Quinolones
Published in European journal of organic chemistry (02-12-2018)“…C–H activation has emerged as a viable alternative to traditional C–C bond forming reactions such as the Suzuki–Miyaura, Stille, Negishi and others. However,…”
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4
Variant offset-type platinum group element reef mineralization in basal olivine cumulates of the Kapalagulu Intrusion, western Tanzania
Published in Economic geology and the bulletin of the Society of Economic Geologists (01-06-2021)“…The Kapalagulu Intrusion in eastern Tanzania hosts a major, 420-m-thick, stratiform/stratabound platinum group element (PGE)-bearing sulfide zone-the Lubalisi…”
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Biochar–root interactions are mediated by biochar nutrient content and impacts on soil nutrient availability
Published in European journal of soil science (2014)“…Roots are the first point of contact between biochar particles and growing plants, yet detailed studies of biochar–root interactions are few. Biochar may…”
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6
Myc Depletion Induces a Pluripotent Dormant State Mimicking Diapause
Published in Cell (11-02-2016)“…Mouse embryonic stem cells (ESCs) are maintained in a naive ground state of pluripotency in the presence of MEK and GSK3 inhibitors. Here, we show that…”
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TGF-β signaling: critical nexus of fibrogenesis and cancer
Published in Journal of translational medicine (26-06-2024)“…The transforming growth factor-beta (TGF-β) signaling pathway is a vital regulator of cell proliferation, differentiation, apoptosis, and extracellular matrix…”
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IFNα-mediated remodeling of endothelial cells in the bone marrow niche
Published in Haematologica (Roma) (01-03-2017)“…In the bone marrow, endothelial cells are a major component of the hematopoietic stem cell vascular niche and are a first line of defense against inflammatory…”
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Characterization of cephalosporin and fluoroquinolone resistant Enterobacterales from Irish farm waste by whole genome sequencing
Published in Frontiers in microbiology (22-03-2023)“…The Enterobacterales are a group of Gram-negative bacteria frequently exhibiting extended antimicrobial resistance (AMR) and involved in the transmission of…”
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10
Regioselective Chlorination and Suzuki–Miyaura Cross‐Coupling of 4‐Alkoxycoumarins, 4‐Alkoxy‐2‐pyrones, and Related Heterocycles
Published in European journal of organic chemistry (01-09-2017)“…Chlorination of the coumarin framework was achieved by using trichloroisocyanuric acid, which has several advantages over N‐chlorosuccinimide, particularly…”
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Imaging at the nexus: how state of the art imaging techniques can enhance our understanding of cancer and fibrosis
Published in Journal of translational medicine (13-06-2024)“…Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways resulting in an altered cellular microenvironment which ultimately…”
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Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma
Published in PloS one (27-07-2018)“…The expression of Sialyl-Tn (STn) in tumors is associated with metastatic disease, poor prognosis, and reduced overall survival. STn is expressed on ovarian…”
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13
Age and sex effects on corpus callosum morphology across the lifespan
Published in Human brain mapping (01-07-2015)“…The corpus callosum (CC) is the largest interhemispheric white matter tract in the human brain, and is characterized by pronounced differences in morphology…”
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Archean komatiitic sill-hosted chromite deposits in the Zimbabwe Craton
Published in Economic geology and the bulletin of the Society of Economic Geologists (01-08-2008)“…Lenticular chromite deposits of widely varying age, metamorphic grade and strain rate, as well as size, shape, and ore quality, are widespread in greenschist…”
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Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation
Published in Cell cycle (Georgetown, Tex.) (01-11-2011)“…DNA damaging agents are widely used in treatment of hematogical malignancies and solid tumors. While effects on hematopoietic stem cells have been…”
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Synchronized mechanical ventilation for respiratory support in newborn infants
Published in Cochrane database of systematic reviews (01-01-2008)“…During synchronized mechanical ventilation, positive airway pressure and spontaneous inspiration coincide. If synchronous ventilation is provoked, adequate gas…”
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Hematopoietic stem cells, infection, and the niche
Published in Annals of the New York Academy of Sciences (01-03-2014)“…The immune response to infection is a rapid and multifaceted process. Infection affects homeostasis within the hematopoietic stem cell (HSC) niche, as lost…”
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Comparison of Physical Fitness Parameters for Starters vs. Nonstarters in an NCAA Division I Menʼs Lacrosse Team
Published in Journal of strength and conditioning research (01-11-2018)“…ABSTRACTSell, KM, Prendergast, JM, Ghigiarelli, JJ, Gonzalez, AM, Biscardi, LM, Jajtner, AR, and Rothstein, AS. Comparison of physical fitness parameters for…”
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Doxorubicin induces the DNA damage response in cultured human mesenchymal stem cells
Published in International journal of hematology (01-11-2012)“…Anthracyclines, including doxorubicin, are widely used in the treatment of leukemia. While the effects of doxorubicin on hematopoietic cells have been…”
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Genomic diversity of Salmonella enterica -The UoWUCC 10K genomes project
Published in Wellcome open research (01-02-2021)“…Background: Most publicly available genomes of Salmonella enterica are from human disease in the US and the UK, or from domesticated animals in the US…”
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