Search Results - "Prem, Smrithi"

Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells by Prem, Smrithi, Dev, Bharati, Peng, Cynthia, Mehta, Monal, Alibutud, Rohan, Connacher, Robert J, St Thomas, Madeline, Zhou, Xiaofeng, Matteson, Paul, Xing, Jinchuan, Millonig, James H, DiCicco-Bloom, Emanuel

“…Autism spectrum disorder (ASD) is defined by common behavioral characteristics, raising the possibility of shared pathogenic mechanisms. Yet, vast clinical and…”
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Autism NPCs from both idiopathic and CNV 16p11.2 deletion patients exhibit dysregulation of proliferation and mitogenic responses by Connacher, Robert, Williams, Madeline, Prem, Smrithi, Yeung, Percy L., Matteson, Paul, Mehta, Monal, Markov, Anna, Peng, Cynthia, Zhou, Xiaofeng, McDermott, Courtney R., Pang, Zhiping P., Flax, Judy, Brzustowicz, Linda, Lu, Che-Wei, Millonig, James H., DiCicco-Bloom, Emanuel

“…Neural precursor cell (NPC) dysfunction has been consistently implicated in autism. Induced pluripotent stem cell (iPSC)-derived NPCs from two autism groups…”
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RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes by Kearse, Michael G., Ireland, Jill A., Prem, Smrithi M., Chen, Alex S., Ware, Vassie C.

“…Duplicated ribosomal protein (Rp) gene families often encode highly similar or identical proteins with redundant or unique roles. Eukaryotic-specific…”
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Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior by Genestine, Matthieu, Lin, Lulu, Durens, Madel, Yan, Yan, Jiang, Yiqin, Prem, Smrithi, Bailoor, Kunal, Kelly, Brian, Sonsalla, Patricia K, Matteson, Paul G, Silverman, Jill, Crawley, Jacqueline N, Millonig, James H, DiCicco-Bloom, Emanuel

“…Many genes involved in brain development have been associated with human neurodevelopmental disorders, but underlying pathophysiological mechanisms remain…”
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Autism Human Neural Precursor Cells Exhibit Common Defects in Neurite Outgrowth, Cell Migration, and mTOR Signaling by Prem, Smrithi

“…Autism spectrum disorders (ASD) are a group of developmental disorders characterized by deficits in social interaction and communication and the presence of…”
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Autism NPCs from both idiopathic and CNV 16p11.2 deletion patients exhibit dysregulation of proliferation and mitogenic responses by Connacher, Robert, Williams, Madeline, Prem, Smrithi, Yeung, Percy L., Matteson, Paul, Mehta, Monal, Markov, Anna, Peng, Cynthia, Zhou, Xiaofeng, McDermott, Courtney R., Pang, Zhiping P., Flax, Judy, Brzustowicz, Linda, Lu, Che-Wei, Millonig, James H., DiCicco-Bloom, Emanuel

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Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs) by Williams, Madeline, Prem, Smrithi, Zhou, Xiaofeng, Matteson, Paul, Yeung, Percy Luk, Lu, Chi-Wei, Pang, Zhiping, Brzustowicz, Linda, Millonig, James H, Dicicco-Bloom, Emanuel

“…Human brain development proceeds through a series of precisely orchestrated processes, with earlier stages distinguished by proliferation, migration, and…”
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Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells (NPCs) by Williams, Madeline, Prem, Smrithi, Zhou, Xiaofeng, Matteson, Paul, Yeung, Percy Luk, Lu, Chi-Wei, Pang, Zhiping, Brzustowicz, Linda, Millonig, James H., Dicicco-Bloom, Emanuel

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