Search Results - "Preiningerova, Jana"
-
1
Is retina affected in Huntington's disease? Is optical coherence tomography a good biomarker?
Published in PloS one (24-02-2023)“…Comparative cross-sectional study of retinal parameters in Huntington's disease and their evaluation as marker of disease progression. Huntington's disease…”
Get full text
Journal Article -
2
Why patients with multiple sclerosis perceive improvement of gait during treatment with natalizumab?
Published in Journal of Neural Transmission (01-06-2019)“…Gait impairment is one of the common manifestations of multiple sclerosis (MS) and contributes to a loss of quality of life. Natalizumab, an anti-α4 integrin…”
Get full text
Journal Article -
3
Spatial and temporal characteristics of gait as outcome measures in multiple sclerosis (EDSS 0 to 6.5)
Published in Journal of neuroengineering and rehabilitation (10-02-2015)“…Gait impairment represents one of the most common and disabling symptom of multiple sclerosis. Quantification of the gait is an important aspect of clinical…”
Get full text
Journal Article -
4
Biofeedback Based Home Balance Training can Improve Balance but Not Gait in People with Multiple Sclerosis
Published in Multiple sclerosis international (2019)“…Background. Impaired balance is common in people with multiple sclerosis (MS) and can be present even in those with a mild disability level. With increasing…”
Get full text
Journal Article -
5
Validation of the Czech Version of the Dysphagia in Multiple Sclerosis Questionnaire (DYMUS)
Published in Dysphagia (01-08-2023)“…Dysphagia is a common symptom of neurological disease, including multiple sclerosis (MS). The DYsphagia in MUltiple Sclerosis (DYMUS) questionnaire was…”
Get full text
Journal Article -
6
Quantification of Gait Abnormalities in Healthy-Looking Multiple Sclerosis Patients (with Expanded Disability Status Scale 0-1.5)
Published in European neurology (01-01-2016)“…Gait impairment is a common symptom in multiple sclerosis (MS) patients, but there is a lack of evidence about gait performance in the group of MS patients…”
Get more information
Journal Article -
7
Oral simvastatin treatment in relapsing-remitting multiple sclerosis
Published in The Lancet (British edition) (15-05-2004)“…Many drugs have been approved for relapsing forms of multiple sclerosis but are only partly effective, are injected, and are expensive. We aimed to investigate…”
Get full text
Journal Article -
8
Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis
Published in BMC neurology (19-07-2022)“…Abstract Background Early infratentorial and focal spinal cord lesions on magnetic resonance imaging (MRI) are associated with a higher risk of long-term…”
Get full text
Journal Article -
9
Long-term outcomes in patients presenting with optic neuritis: Analyses of the MSBase registry
Published in Journal of the neurological sciences (15-11-2021)“…Short-term outcomes of optic neuritis (ON) have been well characterized. Limited data exists on longer-term visual outcomes in patients who present with ON…”
Get full text
Journal Article -
10
Combining clinical and magnetic resonance imaging markers enhances prediction of 12-year employment status in multiple sclerosis patients
Published in Journal of the neurological sciences (15-05-2018)“…Multiple sclerosis (MS) is frequently diagnosed in the most productive years of adulthood and is often associated with worsening employment status. However,…”
Get full text
Journal Article -
11
The regulator’s perspective: How should new therapies and follow-on products for MS be clinically evaluated in the future?
Published in Multiple sclerosis (01-08-2016)“…Background: Although there is still no cure for multiple sclerosis (MS), the introduction of several innovative drugs with modes of action different from that…”
Get full text
Journal Article -
12
Changes of Retina Are Not Involved in the Genesis of Visual Hallucinations in Parkinson's Disease
Published in Parkinson's disease (01-01-2015)“…Parkinson’s disease (PD) is characterized by motor and nonmotor symptoms. Nonmotor symptoms include primarily visual hallucinations (VH). The aim of our study…”
Get full text
Journal Article -
13
Do eyes with and without optic neuritis in multiple sclerosis age equally?
Published in Neuropsychiatric disease and treatment (01-01-2018)“…Anterior visual pathway reflects axonal loss caused by both optic neuritis (ON) and neurodegeneration in multiple sclerosis (MS). Although the axonal injury…”
Get full text
Journal Article -
14
Multiple Sclerosis and Microbiome
Published in Biomolecules (Basel, Switzerland) (11-03-2022)“…The composition of microbiota and the gut-brain axis is increasingly considered a factor in the development of various pathological conditions. The etiology of…”
Get full text
Journal Article -
15
Daclizumab high-yield process in the treatment of relapsing–remitting multiple sclerosis
Published in Therapeutic Advances in Neurological Disorders (01-01-2017)“…Daclizumab is a humanized monoclonal antibody that binds to the α subunit (CD25) of the interleukin-2 receptor and favorably modulates the immune environment…”
Get full text
Book Review Journal Article -
16
Additive Effect of Spinal Cord Volume, Diffuse and Focal Cord Pathology on Disability in Multiple Sclerosis
Published in Frontiers in neurology (06-08-2019)“…Spinal cord (SC) pathology is strongly associated with disability in multiple sclerosis (MS). We aimed to evaluate the association between focal and diffuse SC…”
Get full text
Journal Article -
17
Transplantation of Cryopreserved Adult Human Schwann Cells Enhances Axonal Conduction in Demyelinated Spinal Cord
Published in The Journal of neuroscience (01-02-2001)“…Schwann cells derived from human sural nerve may provide a valuable source of tissue for a cell-based therapy in multiple sclerosis. However, it is essential…”
Get full text
Journal Article -
18
Recommendations for the Use of Prolonged‐Release Fampridine in Patients with Multiple Sclerosis (MS)
Published in CNS neuroscience & therapeutics (01-05-2013)“…Summary Prolonged‐release fampridine (fampridine PR) is a potassium channel blocker that improves conductivity of signal on demyelinated axons in central…”
Get full text
Journal Article -
19
Recombinant T-Cell Receptor Ligand (RTL) for Treatment of Multiple Sclerosis: A Double-Blind, Placebo-Controlled, Phase 1, Dose-Escalation Study
Published in Autoimmune Diseases (01-01-2012)“…Background. Recombinant T-cell receptor ligand 1000 (RTL1000) is a single-chain protein construct containing the outer two domains of HLA-DR2 linked to…”
Get full text
Journal Article -
20
Oral laquinimod therapy in relapsing multiple sclerosis
Published in Expert opinion on investigational drugs (01-07-2009)“…Multiple sclerosis (MS) is a chronic autoimmune disease of the CNS. Early treatment reduces the number of relapses, limits progression of disability, and…”
Get more information
Journal Article