Search Results - "Pregnolato, Marco"
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1
BANP opens chromatin and activates CpG-island-regulated genes
Published in Nature (London) (05-08-2021)“…The majority of gene transcripts generated by RNA polymerase II in mammalian genomes initiate at CpG island (CGI) promoters 1 , 2 , yet our understanding of…”
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2
PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma
Published in Nature communications (20-08-2019)“…Transcription factor networks shape the gene expression programs responsible for normal cell identity and pathogenic state. Using Core Regulatory Circuitry…”
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3
Genome access is transcription factor-specific and defined by nucleosome position
Published in Molecular cell (19-09-2024)“…Mammalian gene expression is controlled by transcription factors (TFs) that engage sequence motifs in a chromatinized genome, where nucleosomes can restrict…”
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4
PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
Published in Nature communications (23-06-2015)“…In the liver, insulin-mediated activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway is at the core of metabolic control. Multiple PI3K and Akt…”
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5
PI3K-C2[gamma] is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling
Published in Nature communications (01-06-2015)“…In the liver, insulin-mediated activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway is at the core of metabolic control. Multiple PI3K and Akt…”
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Journal Article