Search Results - "Preece, Michael A"

Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: Longitudinal birth cohort study and analysis by ONG, Ken K. L, PREECE, Michael A, EMMETT, Pauline M, AHMED, Marion L, DUNGER, David B

“…There is remarkably wide variation in rates of infancy growth, however, its regulation is not well understood. We examined the relationship between maternal…”
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Is the Thyrotropin-Releasing Hormone Test Necessary in the Diagnosis of Central Hypothyroidism in Children by Mehta, Ameeta, Hindmarsh, Peter C., Stanhope, Richard G., Brain, Caroline E., Preece, Michael A., Dattani, Mehul T.

“…To determine the value of the TRH test, we analyzed the unstimulated serum T4 and TSH concentrations in 54 children with central hypothyroidism. A TRH test was…”
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Association between postnatal catch-up growth and obesity in childhood: prospective cohort study by Ong, Ken K L, Ahmed, Marion L, Emmett, Pauline M, Preece, Michael A, Dunger, David B

“…AbstractObjective: To identify predictors of postnatal catch-up growth from birth to two years and its relation to size and obesity at five years.Design:…”
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Catch-up Growth or Regression to the Mean? Recovery from Stunting Revisited by Cameron, Noël, Preece, Michael A., Cole, Tim J.

“…An important question for policy is the extent to which catch‐up growth can ease the impact of early stunting. Martorell et al. (1992) showed that stunted…”
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Pharmacokinetic Studies of Recombinant Human Insulin-Like Growth Factor I (rhIGF-I)/rhIGF-Binding Protein-3 Complex Administered to Patients with Growth Hormone Insensitivity Syndrome by Camacho-Hübner, Cecilia, Rose, Stephen, Preece, Michael A., Sleevi, Mark, Storr, Helen L., Miraki-Moud, Farideh, Minuto, Francesco, Frystyk, Jan, Rogol, Alan, Allan, Geoffrey, Sommer, Andreas, Savage, Martin O.

“…Context: GH insensitivity syndrome (GHIS), Laron syndrome, is characterized by severe short stature, high serum GH levels, and very low serum IGF-I and…”
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The role of growth hormone in determining birth size and early postnatal growth, using congenital growth hormone deficiency (GHD) as a model by Mehta, Ameeta, Hindmarsh, Peter C., Stanhope, Richard G., Turton, James P. G., Cole, Tim J., Preece, Michael A., Dattani, Mehul T.

“…Summary Objective  The role of GH in early human growth is unclear. Congenital GH deficiency (CGHD) provides a useful tool to explore this putative role. We…”
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The genetics of the Silver-Russell syndrome by Preece, Michael A

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Duplication of 7p11.2-p13, Including GRB10, in Silver-Russell Syndrome by Monk, David, Wakeling, Emma L, Proud, Virginia, Hitchins, Megan, Abu-Amero, Sayeda N., Stanier, Philip, Preece, Michael A., Moore, Gudrun E

“…Silver-Russell syndrome (SRS) is characterized by pre- and postnatal growth failure and other dysmorphic features. The syndrome is genetically heterogenous,…”
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Longitudinal Study of Leptin Concentrations during Puberty: Sex Differences and Relationship to Changes in Body Composition1 by Ahmed, Marion Lynn, Ong, Ken K. L, Morrell, David J, Cox, Les, Drayer, Nick, Perry, Leslie, Preece, Michael A, Dunger, David B

“…Leptin may have a role in the initiation of puberty and the regulation of subsequent weight gain, but this hypothesis has not been tested by longitudinal…”
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Maternal repression of the human GRB10 gene in the developing central nervous system; evaluation of the role for GRB10 in Silver-Russell syndrome by Hitchins, M P, Monk, D, Bell, G M, Ali, Z, Preece, M A, Stanier, P, Moore, G E

“…The GRB10 gene encodes a growth suppressor and maps to human chromosome 7p11.2-p13. Maternal duplication (matdup) of this region has recently been associated…”
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Chromosome 7p disruptions in Silver Russell syndrome: delineating an imprinted candidate gene region by MONK, David, BENTLEY, Louise, HITCHINS, Megan, MYLER, Rachael A, CLAYTON-SMITH, Jill, ISMAIL, Samira, PRICE, Sue M, PREECE, Michael A, STANIER, Philip, MOORE, Gudrun E

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Genomic Imprinting, Uniparental Disomy and Foetal Growth by Preece, Michael A, Moore, Gudrun E

“…Genomic imprinting is an epigenetic phenomenon identified in the past 15 years. Thus, maternally imprinted genes are only expressed from the paternal allele…”
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DDC and COBL, flanking the imprinted GRB10 gene on 7p12, are biallelically expressed by Hitchins, Megan P, Bentley, Louise, Monk, David, Beechey, Colin, Peters, Jo, Kelsey, Gavin, Ishino, Fumitoshi, Preece, Michael A, Stanier, Philip, Moore, Gudrun E

“…Maternal duplication of human 7p11.2-p13 has been associated with Silver-Russell syndrome (SRS) in two familial cases. GRB10 is the only imprinted gene…”
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Imprinted methylation profiles for proximal mouse chromosomes 11 and 7 as revealed by methylation-sensitive representational difference analysis by Monk, David, Smith, Rachel, Arnaud, Philippe, Preece, Michael A, Stanier, Philip, Beechey, Colin V, Peters, Jo, Kelsey, Gavin, Moore, Gudrun E

“…Proximal mouse Chromosome (Chr) 11 shares regions of orthology with the candidate gene region for the imprinting growth disorder Silver-Russell syndrome (SRS)…”
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Growth, insulin-like growth factor I (IGF-I), and igf-binding proteins 1 and 3 in children with severe liver disease before and after liver transplantation : A longitudinal and cross-sectional study by BUZI, F, BONTEMPELLI, A. M, ALBERTI, D, JONES, J, PILOTTA, A, LOMBARDI, A, GIUSTINA, A, PREECE, M. A

“…We aimed to study the growth and growth factors of children with liver disease before and after liver transplantation (LT). Three observation intervals: 1)…”
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Phenotype: Genotype Relationships in Growth Hormone Insensitivity Syndrome1 by Woods, Katie A, Dastot, Florence, Preece, Michael A, Clark, Adrian J. L, Postel-Vinay, Marie-Catherine, Chatelain, Pierre G, Ranke, Michael B, Rosenfeld, Ron G, Amselem, Serge, Savage, Martin O

“…GH insensitivity syndrome (GHIS) is associated with many different mutations of the GH receptor (GHR) gene. We examined the phenotypic and biochemical features…”
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Longitudinal study of leptin concentrations during puberty : Sex differences and relationship to changes in body composition by AHMED, M. L, ONG, K. K. L, MORRELL, D. J, COX, L, DRAYER, N, PERRY, L, PREECE, M. A, DUNGER, D. B

“…Leptin may have a role in the initiation of puberty and the regulation of subsequent weight gain, but this hypothesis has not been tested by longitudinal…”
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Silver-Russell syndrome: a dissection of the genetic aetiology and candidate chromosomal regions by Hitchins, Megan P, Stanier, Philip, Preece, Michael A, Moore, Gudrun E

“…The main features of Silver-Russell syndrome (SRS) are pre- and postnatal growth restriction and a characteristic small, triangular face. SRS is also…”
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"Friendly fire" in medicine: hormones, homografts, and Creutzfeldt-Jakob disease by Brown, P, Preece, M A, Will, R G

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Chromosome 7p disruptions in Silver Russell syndrome: delineating an imprinted candidate gene region by Monk, David, Bentley, Louise, Hitchins, Megan, Myler, Rachael A, Clayton-Smith, Jill, Ismail, Samira, Price, Sue M, Preece, Michael A, Stanier, Philip, Moore, Gudrun E

“…Silver-Russell syndrome (SRS) is characterised by pre- and postnatal growth restriction (PNGR) and additional dysmorphic features including body asymmetry and…”
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