Search Results - "Preciado, Sara"
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Overriding Ortho–Para Selectivity via a Traceless Directing Group Relay Strategy: The Meta-Selective Arylation of Phenols
Published in Journal of the American Chemical Society (19-03-2014)“…The direct functionalization of phenols at the ortho and para position is generally facilitated by the electron-donating nature of the hydroxyl group…”
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2
New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues
Published in Nature communications (21-05-2015)“…Natural peptides show high degrees of specificity in their biological action. However, their therapeutical profile is severely limited by their conformational…”
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3
Organizational practices as antecedents of the information security management performance: An empirical investigation
Published in Information technology & people (West Linn, Or.) (07-10-2019)“…Purpose The purpose of this paper is to expand current knowledge about the security organizational practices and analyze its effects on the information…”
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4
Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue
Published in Nature communications (09-03-2016)“…Fluorescent antimicrobial peptides are promising structures for in situ , real-time imaging of fungal infection. Here we report a fluorogenic probe to image…”
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5
Multicomponent Reactions for de Novo Synthesis of BODIPY Probes: In Vivo Imaging of Phagocytic Macrophages
Published in Journal of the American Chemical Society (30-10-2013)“…Multicomponent reactions are excellent tools to generate complex structures with broad chemical diversity and fluorescent properties. Herein we describe the…”
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6
The prohibitin-binding compound fluorizoline induces apoptosis in chronic lymphocytic leukemia cells through the upregulation of NOXA and synergizes with ibrutinib, 5-aminoimidazole-4-carboxamide riboside or venetoclax
Published in Haematologica (Roma) (01-09-2017)“…Fluorizoline is a new synthetic molecule that induces apoptosis by selectively targeting prohibitins. In the study herein, the pro-apoptotic effect of…”
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7
A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation
Published in Oncotarget (08-12-2015)“…We previously described diaryl trifluorothiazoline compound 1a (hereafter referred to as fluorizoline) as a first-in-class small molecule that induces…”
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8
A Trifluorinated Thiazoline Scaffold Leading to Pro-apoptotic Agents Targeting Prohibitins
Published in Angewandte Chemie International Edition (15-09-2014)“…A new class of small molecules, with an unprecedented trifluorothiazoline scaffold, were synthesized and their pro‐apoptotic activity was evaluated. With an…”
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Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis
Published in Annals of the rheumatic diseases (01-09-2017)“…Giant-cell arteritis (GCA) is an inflammatory disease of large/medium-sized arteries, frequently involving the temporal arteries (TA). Inflammation-induced…”
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10
Targeting prohibitins induces apoptosis in acute myeloid leukemia cells
Published in Oncotarget (04-10-2016)“…Fluorizoline is a new synthetic molecule that induces apoptosis by selectively targeting prohibitins (PHBs). In this study, the pro-apoptotic effect of…”
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11
Multicomponent reaction access to complex quinolines via oxidation of the Povarov adducts
Published in Beilstein journal of organic chemistry (13-07-2011)“…The tetrahydroquinolines obtained through the Povarov multicomponent reaction have been oxidized to the corresponding quinoline, giving access to a single…”
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12
Carboxylation of Phenols with CO2 at Atmospheric Pressure
Published in Chemistry : a European journal (10-05-2016)“…A convenient and efficient method for the ortho‐carboxylation of phenols under atmospheric CO2 pressure has been developed. This method provides an alternative…”
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13
Synthesis of C‑2 Arylated Tryptophan Amino Acids and Related Compounds through Palladium-Catalyzed C–H Activation
Published in Journal of organic chemistry (16-08-2013)“…Tryptophan (Trp) and tryptophan derivatives are C2-arylated. A C–H activation process allows the preparation of both protected and unprotected arylated-Trp…”
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14
Information Technology and generating business value: An analysis in industrial SMEs
Published in Intangible capital (01-10-2014)“…Purpose: The literature examines the relationship between information technologies and business results mainly through direct relationship between investment…”
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15
A Domino Oxidation/Arylation/Protodecarboxylation Reaction of Salicylaldehydes: Expanded Access to meta-Arylphenols
Published in Chemistry, an Asian journal (04-02-2016)“…A method that allows salicylaldehydes to be efficiently transformed into meta‐arylated phenol derivatives through a cascade…”
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16
Social Media Technologies' Use for the Competitive Information and Knowledge Sharing, and Its Effects on Industrial SMEs' Innovation
Published in Information systems management (01-01-2017)“…The effective use of technologies supporting decision making is essential to companies' survival. Recent studies analyzed social media technologies (SMT) in…”
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Cloud computing in industrial SMEs: identification of the barriers to its adoption and effects of its application
Published in Electronic markets (01-06-2013)“…Cloud computing is a new technological paradigm that may revolutionize how organizations use IT by facilitating delivery of all technology as a service. In the…”
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18
Carboxylation of Phenols with CO 2 at Atmospheric Pressure
Published in Chemistry : a European journal (10-05-2016)“…Abstract A convenient and efficient method for the ortho ‐carboxylation of phenols under atmospheric CO 2 pressure has been developed. This method provides an…”
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19
Carboxylation of Phenols with CO sub(2) at Atmospheric Pressure
Published in Chemistry : a European journal (01-05-2016)“…A convenient and efficient method for the ortho-carboxylation of phenols under atmospheric CO sub(2) pressure has been developed. This method provides an…”
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20
Organizational practices as antecedents of the information security management performance
Published in Information technology & people (West Linn, Or.) (23-09-2019)“…Purpose The purpose of this paper is to expand current knowledge about the security organizational practices and analyze its effects on the information…”
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