Search Results - "Praus, M"
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Integrated Database of Eight Prospective IgG Studies in Primary Immunodeficiency: New Tool for Pooled Analysis
Published in Journal of allergy and clinical immunology (01-02-2012)Get full text
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The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin: Implications for Antiangiogenic Strategies
Published in The Journal of cell biology (19-02-2001)“…The plasminogen (Plg)/plasminogen activator (PA) system plays a key role in cancer progression, presumably via mediating extracellular matrix degradation and…”
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Ksp-cadherin is a functional cell–cell adhesion molecule related to LI-cadherin
Published in Experimental cell research (01-04-2004)“…Ksp- and LI-cadherin are structurally homologous proteins coexpressed with E-cadherin in renal and intestinal epithelia, respectively. Whereas LI-cadherin has…”
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Reduction of tumor cell migration and metastasis by adenoviral gene transfer of plasminogen activator inhibitors
Published in Gene therapy (01-02-1999)“…Recombinant adenoviral vectors expressing u-PA, t-PA, PAI-1 and PAI-2 were employed to correlate the expression of components of the fibrinolytic system with…”
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A randomized phase II study of a new tick-borne encephalitis vaccine using three different doses and two immunization regimens
Published in Vaccine (1992)“…A new, highly purified inactivated tick-borne encephalitis (TBE) vaccine (FSME-Vaccine Behring, BI 71.061) was recently registered in Germany. A multinational…”
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Hemostatic activation and inflammatory response during cardiopulmonary bypass: Impact of heparin management
Published in Anesthesiology (Philadelphia) (01-10-2002)“…Cardiac surgery involving cardiopulmonary bypass (CPB) leads to fulminant activation of the hemostatic-inflammatory system. The authors hypothesized that…”
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Humoral immunity against tick-borne encephalitis virus following manifest disease and active immunization
Published in Vaccine (01-01-1991)“…Humoral immunity against tick-borne encephalitis virus (TBEV) in patients with a well-documented history of naturally acquired tick-borne encephalitis (TBE)…”
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Update on the toxicology and pharmacology of rDSPA alpha 1 (Bat-PA) in animals and humans
Published in Fibrinolysis & proteolysis (01-08-1997)“…The properties of the plasminogen activator of the vampire bat Desmodus rotundus (rDSPA alpha 1), have been studied in both animals and healthy volunteers. In…”
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Phase I Comparability of Recombinant Human Albumin and Human Serum Albumin
Published in Journal of clinical pharmacology (01-01-2005)“…Recombinant human albumin (rHA) is a highly purified animal‐, virus‐, and prion‐free product developed as an alternative to human serum albumin (HSA), to which…”
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Both u‐PA inhibition and vitronectin binding by plasminogen activator inhibitor 1 regulate HT1080 fibrosarcoma cell metastasis
Published in International journal of cancer (20-12-2002)“…Overexpression of plasminogen activator inhibitor 1 (PAI‐1) reduces tumor cell migration in vitro and metastasis in mice in vivo by mechanisms involving either…”
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Prion protein stimulates tissue‐type plasminogen activator‐mediated plasmin generation via a lysine‐binding site on kringle 2
Published in Journal of thrombosis and haemostasis (01-06-2004)“…Recombinant human prion‐protein (PrP23‐231) stimulates plasminogen activation by tissue‐type plasminogen activator (t‐PA). The stimulatory activity is…”
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The Plasma Supplemented Modified Activated Clotting Time for Monitoring of Heparinization During Cardiopulmonary Bypass: A Pilot Investigation
Published in Anesthesia and analgesia (01-07-2002)“…The standard celite or kaolin activated clotting time (ACT) correlates poorly with heparin levels during cardiopulmonary bypass (CPB). We compared a modified…”
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Stimulation of plasminogen activation by recombinant cellular prion protein is conserved in the NH2-terminal fragment PrP23-110
Published in Thrombosis and haemostasis (01-05-2003)“…The cellular prion protein (PrP(c)), tissue-type plasminogen activator (t-PA) and plasminogen are expressed in synaptic membranes in vivo. In the central…”
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Both lysine-clusters of the NH2-terminal prion-protein fragment PrP23-110 are essential for t-PA mediated plasminogen activation
Published in Thrombosis and haemostasis (01-03-2004)“…We have recently shown that the NH(2)-terminal fragment (PrP23-110) of the human cellular prion protein (PrP(c) ) stimulates t-PA mediated plasminogen…”
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Heparin-Level-Based Anticoagulation Management During Cardiopulmonary Bypass: A Pilot Investigation on the Effects of a Half-Dose Aprotinin Protocol on Postoperative Blood Loss and Hemostatic Activation and Inflammatory Response
Published in Anesthesia and analgesia (01-02-2004)“…Cardiac surgery involving cardiopulmonary bypass (CPB) leads to activation of the hemostatic/inflammatory system. We compared the influence of a half-dose…”
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Thrombin receptor and urokinase-type plasminogen activator are colocalized in vascular smooth muscle cells derived from human carotid atherosclerotic plaques
Published in Fibrinolysis (01-06-1996)“…Since the u-PA/uPAR system and thrombin are main contributors to the process of proliferation and migration of vascular smooth muscle cells, which is essential…”
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The intron 6 G/T polymorphism of c-myb oncogene and the risk for coronary in-stent restenosis
Published in Basic research in cardiology (01-07-2004)“…The principle mechanisms leading to the development of atherosclerosis are long-term accumulation of lipids and cell proliferation. We have recently shown that…”
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Alert systems for post-marketing surveillance of adverse drug reactions
Published in Statistics in medicine (30-12-1993)“…When monitoring spontaneous reports of adverse reactions to registered drugs, it is important to detect any change in the number of reported adverse reactions…”
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