Search Results - "Prattes, Juergen"
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The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin
Published in Drugs (New York, N.Y.) (01-10-2021)“…The epidemiology of invasive fungal infections is changing, with new populations at risk and the emergence of resistance caused by the selective pressure from…”
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Antifungal prophylaxis for prevention of COVID-19-associated pulmonary aspergillosis in critically ill patients: an observational study
Published in Critical care (London, England) (15-09-2021)“…Abstract Background Coronavirus disease 19 (COVID-19)-associated pulmonary aspergillosis (CAPA) emerged as important fungal complications in patients with…”
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Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report
Published in Medical mycology case reports (01-03-2021)“…It is not yet known, if critically ill COVID-19 patients are prone to fungal infections. We report a 69-year-old patient without typical risk factors for…”
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Autopsy Proven Pulmonary Mucormycosis Due to Rhizopus microsporus in a Critically Ill COVID-19 Patient with Underlying Hematological Malignancy
Published in Journal of fungi (Basel) (27-01-2021)“…Viral infections can cause acute respiratory distress syndrome (ARDS), consequently leading to susceptibility for secondary pulmonary infections. Over the past…”
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Diagnosis of invasive aspergillosis in hematological malignancy patients: Performance of cytokines, Asp LFD, and Aspergillus PCR in same day blood and bronchoalveolar lavage samples
Published in The Journal of infection (01-09-2018)“…•Blood and BALF biomarkers for diagnosis of invasive aspergillosis were evaluated.•Biomarkers showed overall better performance in BALF compared to blood.•In…”
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Soluble urokinase plasminogen activator receptor (suPAR) predicts critical illness and kidney failure in patients admitted to the intensive care unit
Published in Scientific reports (01-09-2021)“…Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory biomarker and risk factor for kidney diseases, with a potential prognostic value in…”
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COVID-19 associated pulmonary aspergillosis: regional variation in incidence and diagnostic challenges
Published in Intensive care medicine (01-11-2021)Get full text
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COVID-19 in adult acute myeloid leukemia patients: a long-term follow-up study from the European Hematology Association survey (EPICOVIDEHA)
Published in Haematologica (Roma) (01-01-2023)“…Patients with acute myeloid leukemia (AML) are at high risk of dying from coronavirus disease 2019 (COVID-19). The optimal management of AML patients with…”
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Admission levels of Soluble Urokinase Plasminogen Activator Receptor (suPAR) are Associated with the Development of Severe Complications in Hospitalised COVID-19 Patients: A Prospective Cohort Study
Published in International journal of infectious diseases (01-06-2021)“…•suPAR has been suggested as having good prognostic utility for severe complications of COVID-19.•COVID-19 patients with increased suPAR are at high risk of…”
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SuPAR levels in BAL fluid from patients with acute respiratory distress syndrome—a pilot study
Published in Critical care (London, England) (25-09-2020)“…Blood levels of the soluble form of the urokinase plasminogen activator receptor (suPAR) predict mortality in patients with bacteremia and acute kidney injury…”
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Utility of Serum 1,3-β-d-Glucan Testing for Diagnosis and Prognostication in COVID-19-Associated Pulmonary Aspergillosis
Published in Microbiology spectrum (31-05-2022)Get full text
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Blood Aspergillus PCR: The Good, the Bad, and the Ugly
Published in Journal of fungi (Basel) (01-03-2020)“…Invasive (IA) is one of the most common invasive fungal diseases and is accompanied by high morbidity and mortality. In order to maximize patient outcomes and…”
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Reliability of serum 1,3-beta-d-glucan assay in patients undergoing renal replacement therapy: a review of the literature
Published in Mycoses (01-01-2015)“…Summary The serum 1,3‐beta‐d‐glucan (BDG) test is a pan‐fungal serum marker considered to detect the majority of pathogenic fungi, including Aspergillus spp…”
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Multicenter evaluation of a lateral-flow device test for diagnosing invasive pulmonary aspergillosis in ICU patients
Published in Critical care (London, England) (17-04-2015)“…The incidence of invasive pulmonary aspergillosis (IPA) in intensive care unit (ICU) patients is increasing, and early diagnosis of the disease and treatment…”
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Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection
Published in Frontiers in immunology (02-08-2019)“…Molds and other pathogens induce elevated levels of several cytokines, including interleukin (IL)-6 and IL-8. The objective of this study was to investigate…”
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Isavuconazole Treatment in a Mixed Patient Cohort with Invasive Fungal Infections: Outcome, Tolerability and Clinical Implications of Isavuconazole Plasma Concentrations
Published in Journal of fungi (Basel) (01-06-2020)“…Isavuconazole (ISA) is a triazole antifungal agent recommended for treatment of invasive aspergillosis or mucormycosis. The objective of this study was to…”
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Social determinants of health as drivers of fungal disease
Published in EClinicalMedicine (01-12-2023)“…Disparities in social determinants of health (SDOH) play a significant role in causing health inequities globally. The physical environment, including housing…”
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Editorial: Diagnostic Approaches for Aspergillus Infections
Published in Frontiers in microbiology (2019)Get full text
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Evaluation of Galactomannan Testing, the Aspergillus -Specific Lateral-Flow Device Test and Levels of Cytokines in Bronchoalveolar Lavage Fluid for Diagnosis of Chronic Pulmonary Aspergillosis
Published in Frontiers in microbiology (02-10-2018)“…Diagnosis of chronic pulmonary aspergillosis (CPA) is challenging. Symptoms are unspecific or missing, radiological findings are variable and proof of…”
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