Search Results - "Pratt, NR"

The colorectal adenoma-carcinoma sequence by Leslie, A., Carey, F. A., Pratt, N. R., Steele, R. J. C.

“…Background: It is widely accepted that the adenoma–carcinoma sequence represents the process by which most, if not all, colorectal cancers arise. The evidence…”
Get full text

Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas by LESLIE, Amy, PRATT, Norman R, GILLESPIE, Karen, SALES, Mark, KERNOHAN, Neil M, SMITH, Gillian, WOLF, C. Roland, CAREY, Francis A, STEELE, Robert J. C

“…It is widely accepted that both large-scale chromosomal abnormalities and mutation of specific genes, such as APC, K-ras, and/or p53, occur in the majority of…”
Get full text

Relationship between point gene mutation, chromosomal abnormality, and tumour suppressor gene methylation status in colorectal adenomas by Judson, H, Stewart, A, Leslie, A, Pratt, NR, Baty, DU, Steele, RJC, Carey, FA

“…Epigenetic mechanisms in carcinogenesis may have a significant role in the development of colorectal cancer. To investigate this phenomenon in early‐stage…”
Get full text

Chromosomal changes in colorectal adenomas: Relationship to gene mutations and potential for clinical utility by Leslie, Amy, Stewart, Arlene, Baty, David U., Mechan, Dorothy, McGreavey, Louise, Smith, Gillian, Wolf, C. Roland, Sales, Mark, Pratt, Norman R., Steele, Robert J. C., Carey, Francis A.

“…Although the occurrence of both chromosomal aberrations and specific gene mutations in colorectal tumorigenesis is firmly established, the relationship between…”
Get full text

Solid tissue culture for cytogenetic analysis: a collaborative survey for the Association of Clinical Cytogeneticists by Rodgers, C S, Creasy, M R, Fitchett, M, Maliszewska, C T, Pratt, N R, Waters, J J

“…AIMS: To survey the diagnostic service provided by UK laboratories for the culture of solid tissue samples (excluding tumours) and in particular to examine the…”
Get full text

Partial trisomy 12q: a clinically recognisable syndrome. Genetic risks associated with translocations of chromosome 12q by Pratt, N R, Bulugahapitiya, D T

“…A newborn child with an unusual facial appearance and multiple abnormalities was found to be trisomic for a large part of 12q as a result of adjacent 1…”
Get full text

Helpful Material in "Tape" by Pratt, Nellie Ruth

Get full text

Non-random chromosome changes in a herpes-virus-transformed Syrian hamster cell line and its metastatic derivatives by Pratt, N R, Lowther, G W, Rees, R C, Teale, D M, Potter, C W

“…A primary subcutaneous tumour of low spontaneous metastatic capacity, produced after inoculation of Herpes-virus hominis type-2-transformed hamster fibroblasts…”
Get more information