Search Results - "Pratt, Melissa"
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AAV9 Gene Therapy Increases Lifespan and Treats Pathological and Behavioral Abnormalities in a Mouse Model of CLN8-Batten Disease
Published in Molecular therapy (06-01-2021)“…CLN8 disease is a rare form of neuronal ceroid lipofuscinosis caused by biallelic mutations in the CLN8 gene, which encodes a transmembrane endoplasmic…”
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Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease
Published in Frontiers in genetics (24-03-2023)“…CLN3 disease, caused by biallelic mutations in the gene, is a rare pediatric neurodegenerative disease that has no cure or disease modifying treatment. The…”
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Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8mnd mice
Published in Orphanet journal of rare diseases (11-11-2022)“…Abstract Background CLN8-Batten disease (CLN8 disease) is a rare neurodegenerative disorder characterized phenotypically by progressive deterioration of motor…”
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Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach
Published in Molecular therapy. Nucleic acids (12-09-2023)“…Genetic mutations that disrupt open reading frames and cause translation termination are frequent causes of human disease and are difficult to treat due to…”
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Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice
Published in Molecular therapy. Methods & clinical development (12-03-2021)“…Batten disease is a family of rare, fatal, neuropediatric diseases presenting with memory/learning decline, blindness, and loss of motor function. Recently, we…”
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"I Am What I Am Not Yet": A Progress Report on the Study of the Learning Journeys of the First Modern Teaching Artists
Published in Teaching artist journal (02-01-2016)“…This in-process study investigates experiences of Lincoln Center's first teaching artists, connecting their work in the 1970s to contemporary practice…”
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"I Am What I Am Not Yet": A Progress Report on the Study of the Learning Journeys of the First Modern Teaching Artists. From the Field: Reflection & Innovation
Published in Teaching artist journal (2016)“…This in-process study investigates experiences of Lincoln Center's first teaching artists, connecting their work in the 1970s to contemporary practice…”
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Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8 mnd mice
Published in Orphanet journal of rare diseases (11-11-2022)“…CLN8-Batten disease (CLN8 disease) is a rare neurodegenerative disorder characterized phenotypically by progressive deterioration of motor and cognitive…”
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NEW COURTS ON THE BLOCK: SPECIALIZED CRIMINAL COURTS FOR VETERANS IN THE UNITED STATES
Published in Appeal, review of current law and law reform (01-01-2010)Get full text
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Glycerophosphoinositol is Elevated in Blood Samples From pigs, Mice, and CLN3-Affected Individuals
Published in Biomarker insights (01-06-2022)“…Introduction: CLN3 Batten disease is a rare pediatric neurodegenerative lysosomal disorder caused by biallelic disease-associated variants in CLN3. Despite…”
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Glycerophosphoinositol is Elevated in Blood Samples From CLN3Δex7-8 pigs, Cln3Δex7-8 Mice, and CLN3-Affected Individuals
Published in Biomarker insights (01-01-2022)“…Introduction: CLN3 Batten disease is a rare pediatric neurodegenerative lysosomal disorder caused by biallelic disease-associated variants in CLN3. Despite…”
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"I Am What I Am Not Yet": Investigating the Pedagogical Journeys of the First Modern Teaching Artists
Published 01-01-2019“…In 1975, a small number of artists were asked by Lincoln Center to help its new education department, called Lincoln Center Institute, forge a new vision for…”
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Dissertation -
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Sex-split analysis of pathology and motor-behavioral outcomes in a mouse model of CLN8-Batten disease reveals an increased disease burden and trajectory in female Cln8 mnd mice
Published in Orphanet journal of rare diseases (01-11-2022)“…Abstract Background CLN8-Batten disease (CLN8 disease) is a rare neurodegenerative disorder characterized phenotypically by progressive deterioration of motor…”
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Journal Article -
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Inoculation and Colonization of Four Saltmarsh Species with Vesicular-Arbuscular Mycorrhizal Fungi (Mississippi)
Published in Ecological Restoration (01-12-2009)Get full text
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