Search Results - "Pratt, John S."

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  1. 1

    The effect of chronic lorazepam administration in aging mice by Fahey, Jeanne M., Pritchard, Gary A., Reddi, Jyoti M., Pratt, John S., Grassi, Jeffrey M., Shader, Richard I., Greenblatt, David J.

    Published in Brain research (06-11-2006)
    “…To assess benzodiazepine tolerance in aged animals, lorazepam or vehicle was administered chronically to male Crl: CD-1(ICR)BR mice. Pharmacodynamic and…”
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    Journal Article
  2. 2

    Cleavage-Site Mutagenesis Alters Post-translation Processing of Pro-CCK in AtT-20 Cells by Pratt, John S, Blum, Alissa, Vishnuvardhan, Daesety, Kitagawa, Kouki, Beinfeld, Margery C

    Published in Biochemistry (Easton) (27-07-2004)
    “…Cholecystokinin (CCK) is expressed in the central and peripheral nervous systems and functions as a neurotransmitter and neuroendocrine hormone. The in vivo…”
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    Journal Article
  3. 3

    Pharmacodynamic and receptor binding changes during chronic lorazepam administration by Fahey, Jeanne M, Pritchard, Gary A, Grassi, Jeffrey M, Pratt, John S, Shader, Richard I, Greenblatt, David J

    Published in Pharmacology, biochemistry and behavior (01-05-2001)
    “…To assess pharmacodynamic and neurochemical aspects of tolerance, lorazepam (2 mg/kg/day), or vehicle was administered chronically to male Crl: CD-1(ICR)BR…”
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    Journal Article
  4. 4

    Effects of ketoconazole on triazolam pharmacokinetics, pharmacodynamics and benzodiazepine receptor binding in mice by Fahey, J M, Pritchard, G A, Moltke, L L, Pratt, J S, Grassi, J M, Shader, R I, Greenblatt, D J

    “…We previously demonstrated that ketoconazole is a potent inhibitor of triazolam biotransformation in vitro and in vivo. Despite significant elevations in…”
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  5. 5

    In situ hybridization histochemistry as a method to assess GABAAreceptor subunit mRNA expression following chronic alprazolam administration by Fahey, Jeanne M., Pritchard, Gary A., Grassi, Jeffrey M., Pratt, John S., Shader, Richard I., Greenblatt, David J.

    Published in Journal of psychopharmacology (Oxford) (01-05-1999)
    “…Previous work in our laboratory has demonstrated region-specic effects for chronic alprazolam on binding and function at the GABAA receptor. The present study…”
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    Lorazepam Attenuates the Behavioral Effects of Dizocilpine by Fahey, Jeanne M., Pritchard, Gary A., Pratt, John S., Shader, Richard I., Greenblatt, David J.

    Published in Pharmacology, biochemistry and behavior (01-01-1999)
    “…To characterize the potential interaction between the excitatory and inhibitory neurotransmitter systems, the effects of dizocilpine, CPP, and lorazepam on…”
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  9. 9

    In situ hybridization histochemistry as a method to assess GABA(A) receptor subunit mRNA expression following chronic alprazolam administration by Fahey, J M, Pritchard, G A, Grassi, J M, Pratt, J S, Shader, R I, Greenblatt, D J

    “…Previous work in our laboratory has demonstrated region-specific effects for chronic alprazolam on binding and function at the GABA(A) receptor. The present…”
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    Journal Article
  10. 10

    Electroconvulsive shock alters GABAA receptor subunit mRNAs: use of quantitative PCR methodology by Pratt, J S, Kang, I, Bazan, N G, Miller, L G

    Published in Brain research bulletin (1993)
    “…Electroconvulsive shock (ECS) may affect several neurotransmitter systems in brain, including the GABAergic inhibitory system. We used a quantitative PCR-based…”
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