Search Results - "Pratt, John S."
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The effect of chronic lorazepam administration in aging mice
Published in Brain research (06-11-2006)“…To assess benzodiazepine tolerance in aged animals, lorazepam or vehicle was administered chronically to male Crl: CD-1(ICR)BR mice. Pharmacodynamic and…”
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Cleavage-Site Mutagenesis Alters Post-translation Processing of Pro-CCK in AtT-20 Cells
Published in Biochemistry (Easton) (27-07-2004)“…Cholecystokinin (CCK) is expressed in the central and peripheral nervous systems and functions as a neurotransmitter and neuroendocrine hormone. The in vivo…”
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Pharmacodynamic and receptor binding changes during chronic lorazepam administration
Published in Pharmacology, biochemistry and behavior (01-05-2001)“…To assess pharmacodynamic and neurochemical aspects of tolerance, lorazepam (2 mg/kg/day), or vehicle was administered chronically to male Crl: CD-1(ICR)BR…”
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Effects of ketoconazole on triazolam pharmacokinetics, pharmacodynamics and benzodiazepine receptor binding in mice
Published in The Journal of pharmacology and experimental therapeutics (01-04-1998)“…We previously demonstrated that ketoconazole is a potent inhibitor of triazolam biotransformation in vitro and in vivo. Despite significant elevations in…”
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In situ hybridization histochemistry as a method to assess GABAAreceptor subunit mRNA expression following chronic alprazolam administration
Published in Journal of psychopharmacology (Oxford) (01-05-1999)“…Previous work in our laboratory has demonstrated region-specic effects for chronic alprazolam on binding and function at the GABAA receptor. The present study…”
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Identification of a CCK-B/GASTRIN receptor amino acid determinant of inverse agonist activity
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2000)Get full text
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National Health Service
Published in British Medical Journal (21-02-1948)Get full text
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Lorazepam Attenuates the Behavioral Effects of Dizocilpine
Published in Pharmacology, biochemistry and behavior (01-01-1999)“…To characterize the potential interaction between the excitatory and inhibitory neurotransmitter systems, the effects of dizocilpine, CPP, and lorazepam on…”
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In situ hybridization histochemistry as a method to assess GABA(A) receptor subunit mRNA expression following chronic alprazolam administration
Published in Journal of psychopharmacology (Oxford) (1999)“…Previous work in our laboratory has demonstrated region-specific effects for chronic alprazolam on binding and function at the GABA(A) receptor. The present…”
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Electroconvulsive shock alters GABAA receptor subunit mRNAs: use of quantitative PCR methodology
Published in Brain research bulletin (1993)“…Electroconvulsive shock (ECS) may affect several neurotransmitter systems in brain, including the GABAergic inhibitory system. We used a quantitative PCR-based…”
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Catastrophic nuclear power reactor accidents: an issue of safety, a question of record [consideration given by United States nuclear regulatory agencies to the likelihood and consequences of a catastrophic nuclear reactor accident]
Published in Georgia law review (Athens, Ga. : 1966) (01-01-1980)Get full text
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CATASTROPHIC NUCLEAR POWER REACTOR ACCIDENTS: AN ISSUE OF SAFETY, A QUESTION OF RECORD
Published in Georgia law review (Athens, Ga. : 1966) (01-01-1979)Get full text
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