Search Results - "Pratsch, Gerald"

Constructing Quaternary Carbons from N‑(Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis by Pratsch, Gerald, Lackner, Gregory L, Overman, Larry E

“…Tertiary carbon radicals have notable utility for uniting complex carbon fragments with concomitant formation of new quaternary carbons. This article explores…”
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Radical Arylation of Phenols, Phenyl Ethers, and Furans by Wetzel, Alexander, Pratsch, Gerald, Kolb, Roman, Heinrich, Markus R.

“…Radical arylations of para‐substituted phenols and phenyl ethers proceeded with good regioselectivity at the ortho position with respect to the hydroxy or…”
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Fragment Coupling and the Construction of Quaternary Carbons Using Tertiary Radicals Generated From tert-Alkyl N‑Phthalimidoyl Oxalates By Visible-Light Photocatalysis by Lackner, Gregory L, Quasdorf, Kyle W, Pratsch, Gerald, Overman, Larry E

“…The coupling of tertiary carbon radicals with alkene acceptors is an underdeveloped strategy for uniting complex carbon fragments and forming new quaternary…”
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The Gomberg-Bachmann Reaction for the Arylation of Anilines with Aryl Diazotates by Pratsch, Gerald, Wallaschkowski, Tina, Heinrich, Markus R.

“…Simply aqueous sodium hydroxide is sufficient to exclude ionic side reactions and to prepare 2‐aminobiphenyls from aryl diazotates and anilines through a new…”
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Synthesis of 2,5-Diaryl-1,5-dienes from Allylic Bromides Using Visible-Light Photoredox Catalysis by Pratsch, Gerald, Overman, Larry E

“…Visible-light photoreductive coupling of 2-arylallyl bromides in the presence of the photocatalyst Ru­(bpy)3(PF6)2, a Hantzsch ester, and i-Pr2NEt gives…”
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The Trapping of Phenyldiazenes in Cycloaddition Reactions by Fehler, Stefanie K., Pratsch, Gerald, Heinrich, Markus R.

“…The reactivity of phenyldiazenes was studied intensively in the late 1960s, but not much is known about their behavior under acidic conditions. Based on the…”
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Hydroxy- and Aminophenyl Radicals from Arenediazonium Salts by Pratsch, Gerald, Anger, Christian A., Ritter, Katharina, Heinrich, Markus R.

“…Arenediazonium salts are well‐known sources of aryl radicals; however, the hydroxy‐ and amino‐substituted derivatives 1, 2, and 3, which lead to the respective…”
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Aryl Radical Selectivity in Biphasic Systems by Altmann, Lisa-Marie, Fürst, Michael C. D, Gans, Eva I, Zantop, Viviane, Pratsch, Gerald, Heinrich, Markus R

“…Aryl radicals generated in the aqueous phase of biphasic mixtures haveregardless of a comparably low polarity a strong preference to react with aromatic…”
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Regiospecific Introduction of Halogens on the 2‑Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists by Fischer, Oliver, Hofmann, Josefa, Rampp, Hannelore, Kaindl, Jonas, Pratsch, Gerald, Bartuschat, Amelie, Taudte, R. Verena, Fromm, Martin F, Hübner, Harald, Gmeiner, Peter, Heinrich, Markus R

“…Muscarinic M3 receptor antagonists and inverse agonists displaying high affinity and subtype selectivity over the antitarget M2 are valuable pharmacological…”
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Constructing Quaternary Carbons from (N-Acyloxy)phthalimide Precursors of Tertiary Radicals Using Visible-Light Photocatalysis by Pratsch, Gerald, Lackner, Gregory L., Overman, Larry E.

“…Tertiary carbon radicals have notable utility for uniting complex carbon fragments with concomitant formation of new quaternary carbons. This article explores…”
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Radical arylation of tyrosine residues in peptides by Fehler, Stefanie K., Pratsch, Gerald, Östreicher, Christiane, Fürst, Michael C.D., Pischetsrieder, Monika, Heinrich, Markus R.

“…The radical arylation of the phenolic side chain of tyrosine in peptides was investigated. Aryl radicals were generated from aryldiazonium salts using…”
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Modern developments in aryl radical chemistry by Pratsch, Gerald, Heinrich, Markus R

“…This review summarizes recent advances in the field of aryl radical chemistry. In particular, modern developments of the well-known Meerwein, Pschorr, and…”
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Radical arylation of tyrosine and its application in the synthesis of a highly selective neurotensin receptor 2 ligand by Pratsch, Gerald, Unfried, Johannes F, Einsiedel, Jürgen, Plomer, Manuel, Hübner, Harald, Gmeiner, Peter, Heinrich, Markus R

“…A small library of Fmoc-protected 3-arylated tyrosines was created by radical arylation. The new building blocks were successfully applied in the synthesis of…”
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Synthesis and biological evaluation of 3-aryltyramines as fragments binding to BACE-1 and BACE-2 by Fehler, Stefanie K., Pratsch, Gerald, Huber, Walter, Gast, Alain, Hochstrasser, Remo, Hennig, Michael, Heinrich, Markus R.

“…3-Aryltyramines were prepared in one single step from tyramine and various arenediazonium salts by radical arylation. Binding as well as enzyme inhibition data…”
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Phenyldiazene - abgefangen in Cycloadditionsreaktionen by Fehler, Stefanie K., Pratsch, Gerald, Heinrich, Markus R.

“…Die Reaktivität von Phenyldiazenen wurde zum Ende der 1960er Jahre intensiv untersucht, doch ist bisher kaum etwas über ihr Verhalten unter sauren Bedingungen…”
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