Search Results - "Prato, Sandro"

Selective suicide of cross-presenting CD8⁺ dendritic cells by cytochrome c injection shows functional heterogeneity within this subset by Lin, Ming Lee, Zhan, Yifan, Proietto, Anna I, Prato, Sandro, Wu, Li, Heath, William R, Villadangos, Jose A, Lew, Andrew M

“…Cross-presentation as a fundamental pathway of activating CD8⁺ T cells has been well established. So far the application of this concept in vivo is limited,…”
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Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells by Wylie, Ben, Seppanen, Elke, Xiao, Kun, Zemek, Rachael, Zanker, Damien, Prato, Sandro, Foley, Bree, Hart, Prue H, Kroczek, Richard A, Chen, Weisan, Waithman, Jason

“…The question of which dendritic cells (DCs) cross-present peripheral tumor antigens remains unanswered. We assessed the ability of multiple skin-derived and…”
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HLA-DR+ Immature Cells Exhibit Reduced Antigen-Presenting Cell Function But Respond to CD40 Stimulation by Pinzon-Charry, Alberto, Maxwell, Tammy, Prato, Sandro, Furnival, Colin, Schmidt, Chris, López, José Alejandro

“…Dendritic cells (DC) have been implicated in the defective function of the immune system during cancer progression. We have demonstrated that patients with…”
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Therapeutic ISCOMATRIX™ adjuvant vaccine elicits effective anti-tumor immunity in the TRAMP-C1 mouse model of prostate cancer by Barr, Adele M., Silva, Anabel, Prato, Sandro, Belz, Gabrielle T., Maraskovsky, Eugene, Baz Morelli, Adriana

“…Cancer vaccine development has proven challenging with the exception of some virally induced cancers for which prophylactic vaccines exist. Currently, there is…”
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Target Density, Not Affinity or Avidity of Antigen Recognition, Determines Adoptive T Cell Therapy Outcomes in a Mouse Lymphoma Model by Segal, Gabriela, Prato, Sandro, Zehn, Dietmar, Mintern, Justine D, Villadangos, Jose A

“…Adoptive T cell therapy (ACT) with antitumor CTL is a promising and tailored treatment against cancer. We investigated the role played by the affinity and…”
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Rapid deletion and inactivation of CTLs upon recognition of a number of target cells over a critical threshold by Prato, Sandro, Zhan, Yifan, Mintern, Justine D, Villadangos, Jose A

“…Initiation of CTL responses against foreign pathogens also primes anti-self CTLs. Mechanisms of CTL inactivation inhibit anti-self CTLs to prevent tissue…”
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Transgenic Expression of GM-CSF in T Cells Causes Disseminated Histiocytosis by van Nieuwenhuijze, Annemarie E, Coghill, Elise, Gray, Daniel, Prato, Sandro, Metcalf, Donald, Alexander, Warren S, Wicks, Ian P

“…Recent studies highlight surprising roles for granulocyte-macrophage colony-stimulating factor (GM-CSF) production by T cells. T-cell–derived GM-CSF is…”
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Characterization of an Immediate Splenic Precursor of CD8+ Dendritic Cells Capable of Inducing Antiviral T Cell Responses by Bedoui, Sammy, Prato, Sandro, Mintern, Justine, Gebhardt, Thomas, Zhan, Yifan, Lew, Andrew M, Heath, William R, Villadangos, Jose A, Segura, Elodie

“…Mouse spleens contain three major dendritic cell (DC) populations: plasmacytoid DC, conventional CD8(+)CD24(+) DC (CD8(+) DC), and conventional CD8(-)CD24(-)…”
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Induction of antigen-specific effector-phase tolerance following vaccination against a previously ignored B-cell lymphoma by Prato, Sandro, Mintern, Justine D, Lahoud, Mireille H, Huang, David C, Villadangos, Jose A

“…The mechanisms of immune evasion during haematological malignancies are poorly understood. As lymphomas grow in lymphoid organs, it would be expected that if…”
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Targeting the Gut Vascular Endothelium Induces Gut Effector CD8 T Cell Responses Via Cross-Presentation by Dendritic Cells by Bourges, Dorothee, Zhan, Yifan, Brady, Jamie L, Braley, Hal, Caminschi, Irina, Prato, Sandro, Villadangos, Jose A, Lew, Andrew M

“…Systemic delivery of Ag usually induces poor mucosal immunity. To improve the CD8 T cell response at mucosal sites, we targeted the Ag to MAdCAM-1, a mucosal…”
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Selective suicide of cross-presenting CD8 super(+) dendritic cells by cytochrome c injection shows functional heterogeneity within this subset by Lin, Ming Lee, Zhan, Yifan, Proietto, Anna I, Prato, Sandro, Wu, Li, Heath, William R, Villadangos, Jose A, Lew, Andrew M

“…Cross-presentation as a fundamental pathway of activating CD8 super(+) T cells has been well established. So far the application of this concept in vivo is…”
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HLA-DR+ Immature Cells Exhibit Reduced Antigen-Presenting Cell Function But Respond to CD40 Stimulation1 by Pinzon-Charry, Alberto, Maxwell, Tammy, Prato, Sandro, Furnival, Colin, Schmidt, Chris, López, José Alejandro

“…Dendritic cells (DC) have been implicated in the defective function of the immune system during cancer progression. We have demonstrated that patients with…”
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MHC class I‐restricted exogenous presentation of a synthetic 102‐mer malaria vaccine polypeptide by Prato, Sandro, Maxwell, Tammy, Pinzón‐Charry, Alberto, Schmidt, Christopher William, Corradin, Giampietro, López, José Alejandro

“…The circumsporozoite (CS) is the most abundant surface protein of the Plasmodium sporozoite, and is also present early in the liver stage of the infection…”
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