Search Results - "Pratha, V"

Comparison of the effects of immediate‐release omeprazole oral suspension, delayed‐release lansoprazole capsules and delayed‐release esomeprazole capsules on nocturnal gastric acidity after bedtime dosing in patients with night‐time GERD symptoms by KATZ, P. O., KOCH, F. K., BALLARD, E. D., BAGIN, R. G., GAUTILLE, T. C., CHECANI, G. C., HOGAN, D. L., PRATHA, V. S. V.

“…Summary Background Gastro‐oesophageal reflux disease (GERD) patients on proton pump inhibitors before breakfast or dinner have acid recovery at night. Bedtime…”
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The effect of once daily omeprazole and succinic acid (VECAM) vs once daily omeprazole on 24-h intragastric pH by Chowers, Y., Atarot, T., Pratha, V. S., Fass, R.

“…Background  Parietal cell H+/K+ATPase activation is essential for optimal proton pump inhibitor (PPI) activity. Succinic acid (SA) was shown to induce gastric…”
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Identification of transport abnormalities in duodenal mucosa and duodenal enterocytes from patients with cystic fibrosis by Pratha, Vijaya S., Hogan, Daniel L., Martensson, Birgitta A., Bernard, Joie, Zhou, Rihong, Isenberg, Jon I.

“…Background & Aims: The duodenum is a cystic fibrosis transmembrane conductance regulator (CFTR)-expressing epithelium with high bicarbonate secretory capacity…”
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Oral pantoprazole in the form of granules or tablets are pharmacodynamically equivalent in suppressing acid output in patients with gastro‐oesophageal reflux disease and a history of erosive oesophagitis by HOGAN, D., PRATHA, V., RIFF, D., DUCKER, S., SCHWARTZ, H., SOFFER, E., WANG, W., RATH, N., COMER, G. M.

“…Summary Aim To demonstrate the pharmacodynamic comparability between oral 40 mg pantoprazole delayed‐release granules and tablets. Methods This was a…”
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Effect of intravenous omeprazole on recurrent bleeding after endoscopic treatment of bleeding peptic ulcers by Savides, T J, Pratha, V

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Metabolic Profiles of Montelukast Sodium (Singulair), a Potent Cysteinyl Leukotriene1 Receptor Antagonist, in Human Plasma and Bile by BALANI, S. K, XU, X, FREEMAN, A, HOLLAND, S. D, SCHWARTZ, J. I, LASSETER, K. C, GERTZ, B. J, ISENBERG, J. I, ROGERS, J. D, LIN, J. H, BAILLIE, T. A, PRATHA, V, KOSS, M. A, AMIN, R. D, DUFRESNE, C, MILLER, R. R, ARISON, B. H, DOSS, G. A, CHIBA, M

“…Montelukast sodium [1-{[(1( R )-(3-(2-(7-chloro-2-quinolinyl)-( E )- ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio]methyl}cyclopropylacetic…”
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A role for guanylate cyclase C in acid-stimulated duodenal mucosal bicarbonate secretion by Rao, S P, Sellers, Z, Crombie, D L, Hogan, D L, Mann, E A, Childs, D, Keely, S, Sheil-Puopolo, M, Giannella, R A, Barrett, K E, Isenberg, J I, Pratha, V S

“…Luminal acidification provides the strongest physiological stimulus for duodenal HCO3- secretion. Various neurohumoral mechanisms are believed to play a role…”
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Human duodenal mucosal brush border Na(+)/H(+) exchangers NHE2 and NHE3 alter net bicarbonate movement by Repishti, M, Hogan, D L, Pratha, V, Davydova, L, Donowitz, M, Tse, C M, Isenberg, J I

“…The proximal duodenal mucosa secretes HCO that serves to protect the epithelium from injury. In isolated human duodenal enterocytes in vitro, multiple luminal…”
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Synthesis or rupture: duration of acid inhibition by proton pump inhibitors by Sachs, G, Shin, J M, Pratha, V, Hogan, D

“…Insight has been gained into the relationship between the structure of proton pump inhibitors (PPIs), their binding, and their suppression of acid secretion…”
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Utility of endoscopic biopsy samples to quantitate human duodenal ion transport by Pratha, Vijaya S., Thompson, Stephen M., Hogan, Daniel L., Paulus, Petra, Dreilinger, Anna D., Barrett, Kim E., Isenberg, Jon I.

“…Duodenal mucosal bicarbonate secretion (DMBS) prevents acid-peptic damage and facilitates nutrient absorption. DMBS is diminished in patients with duodenal…”
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Pantoprazole positively impacts nighttime heartburn symptoms and quality of sleep in patients with gastroesophageal reflux disease by Pratha, Vijaya, Wan, George J., Soffer, Elaine, Hogan, Daniel, Wang, Wenjin

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Pantoprazole is more effective than ranitidine in reducing the duration of esophageal acid contact by Pratha, Vijaya S., Soffer, Elaine, Hogan, Daniel L., Wang, Wenjin

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Gastric pH above 2.5 is of limited use as a measure of acid inhibition by Pratha, Vijaya S., Lynn, Richard B., Karlstadt, Robyn G., Burton, Michael S., Hogan, Daniel L.

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Pantoprazole effectively decreases the number of long reflux episodes by day 1 of therapy by Pratha, Vijaya S., Hogan, Daniel L., Munjal, Sagar, Karlstadt, Robyn G., Lynn, Richard B., Burton, Michael S.

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Oral and intravenous dosage forms of pantoprazole are equivalent in their ability to suppress gastric acid secretion in patients with gastroesophageal reflux disease by Metz, David C, Pratha, Vijaya, Martin, Patrick, Paul, Jeffrey, Maton, Paul N, Lew, Edward, Pisegna, Joseph R

“…The aim of this study was to assess the ability of pantoprazole to maintain gastric acid suppression in patients with gastroesophageal reflux disease who are…”
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In erosive gerd patients decreased esophageal acid exposure is more important than prolonged periods of gastric acid inhibition by Pratha, Vijaya S, Karlstadt, Robyn G, Lynn, Richard B, Burton, Michael S, Hogan, Daniel L

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Pantoprazole affords long-term inhibition of pentagastrin-stimulated gastric acid secretion in healthy subjects by Pratha, Vijaya S, Karlstadt, Robyn G, Lynn, Richard B, Burton, Michael S, Hogan, Daniel L

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Gastric PH may not be an accurate indicator of gastric acidity by Pratha, Vijaya, Karlstadt, Robyn, Lynn, Richard B., Lane, James R., Hogan, Daniel L.

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Relationship between gastric and esophageal pH in erosive GERD by Pratha, Vijaya, Karlstadt, Robyn, Lynn, Richard B, Lane, James R, Hogan, Daniel L

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Heat stable toxin of E. coli (STa) stimulates duodenal mucosal bicarbonate secretion in cystic fibrosis knockout mice by CHILDS, D, CROMBIE, D, PRATHA, V, SELLERS, Z, HOGAN, D, ISENBERG, J

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