Search Results - "Pratap, V."

Development of Kinase-Centric Drugs: A Computational Perspective by Gajulapalli, V Pratap Reddy

“…Kinases are involved in signal transduction, physiological responses, and diseases like cancer, neurological disorders, and autoimmune disorders, making them…”
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Endoscopic and clinical responses to anti‐tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease by Pratap Mouli, V., Munot, K., Ananthakrishnan, A., Kedia, S., Addagalla, S., Garg, S. K., Benjamin, J., Singla, V., Dhingra, R., Tiwari, V., Bopanna, S., Hutfless, S., Makharia, G., Ahuja, V.

“…Summary Background Differentiation between intestinal tuberculosis and Crohn's disease is difficult and may require therapeutic trial with anti‐tubercular…”
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Novel cocrystals of brexpiprazole with improved solubility by Rama, Veeraswamy, Vidavulur, Siddaiah, Tadikonda, Pratap V., Rajana, Nagaraju, Mittapalli, Sudhir

“…[Display omitted] •Prepared novel cocrystals of brexpiprazole with biologically acceptable coformers.•All the cocrystals were completely characterized by PXRD,…”
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Letter: mucosal response in discriminating intestinal tuberculosis from Crohn's disease—when to look for it? Authors' reply by Pratap Mouli, V., Kedia, S., Ahuja, V.

“…Linked content This article is linked to Pratap Mouli et al and Sharma et al papers. To view these articles visit https://doi.org/10.1111/apt.13840 and…”
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Organocatalytic asymmetric decarboxylative cyanomethylation of isatins using L-proline derived bifunctional thiourea by Pratap Reddy Gajulapalli, V, Vinayagam, Poopathy, Kesavan, Venkitasamy

“…First asymmetric decarboxylative cyanomethylation of isatins is reported herewith using bifunctional thiourea derived from l-proline in good yields and…”
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CD4+ CD25+ FOXP3+ T cell frequency in the peripheral blood is a biomarker that distinguishes intestinal tuberculosis from Crohn's disease by Tiwari, Veena, Kedia, Saurabh, Garg, Sushil Kumar, Rampal, Ritika, Mouli, V Pratap, Purwar, Anuja, Mitra, D K, Das, Prasenjit, Dattagupta, S, Makharia, Govind, Acharya, S K, Ahuja, Vineet

“…Distinguishing between Crohn's Disease (CD) and Intestinal Tuberculosis (ITB) has been a challenging task for clinicians due to their similar presentation…”
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Are We Creating Outcomes Similar to Power Sector by Proliferating Metro Rail Across Cities in India? by Pratap, Kumar V.

“…Metro rails mitigate problems of pollution and congestion in crowded Indian cities and are therefore a priority of the government. However, they are also very…”
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Differential fine-regulation of enzyme driven ROS detoxification network imparts salt tolerance in contrasting peanut genotypes by Chakraborty, Koushik, Bishi, Sujit K., Goswami, Nisha, Singh, Amrit L., Zala, Pratap V.

“…[Display omitted] •Salinity produced differential ROS load in tolerant and sensitive peanut genotypes.•Major detoxification and fine regulation of H2O2…”
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Design, synthesis, and biological evaluation of N-arylpiperazine derivatives as interferon inducers by Chu, Yeonjeong, Raja Sekhara Reddy, B., Pratap Reddy Gajulapalli, V., Sudhakar Babu, K., Kim, Eunha, Lee, Sanghee

“…[Display omitted] •We designed and synthesized a series of arylpiperazine derivatives as interferon inducers.•We tested different linker system and carbonyl…”
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Ligand-based pharmacophore modelling in search of novel anaplastic lymphoma kinase inhibitors by Pratap Reddy Gajulapalli, V., Lee, Juyong, Sohn, Insuk

“…•Multistep virtual screening in combination with MD simulation was carried out to identify potential inhibitors of Anaplastic Lymphoma Kinase.•Two chemically…”
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Long-Term Disease Course and Pregnancy Outcomes in Women with Inflammatory Bowel Disease: An Indian Cohort Study by Padhan, Rajesh Kumar, Kedia, Saurabh, Garg, Sushil Kumar, Bopanna, Sawan, Mouli, V. Pratap, Dhingra, Rajan, Makharia, Govind, Ahuja, Vineet

“…Background The literature on interaction between pregnancy and inflammatory bowel disease (IBD) is inconsistent, and there are no reports on this aspect from…”
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Prospective validation of CD4+CD25+FOXP3+ T-regulatory cells as an immunological marker to differentiate intestinal tuberculosis from Crohn’s disease by Rampal, Ritika, Kedia, Saurabh, Wari, Mohamad Nahidul, Madhu, Deepak, Singh, Amit Kumar, Tiwari, Veena, Mouli, V. Pratap, Mohta, Srikant, Makharia, Govind, Ahuja, Vineet

“…Background/Aims: Crohn’s disease (CD) and intestinal tuberculosis (ITB) remain “difficult-to-differentiate” diseases. We have previously documented peripheral…”
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Salinity-induced changes in seed germination and the expression profile of antioxidant enzymes in peanut as early and late responses in emerging radicles by Chakraborty, Koushik, Bishi, Sujit K., Goswami, Nisha, Singh, Amrit L., Bhaduri, Debarati, Zala, Pratap V.

“…Reactive oxygen species (ROS) play a critical role in developmental and signal transduction processes during seed germination and early seedling establishment…”
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PfKsgA1 functions as a transcription initiation factor and interacts with the N-terminal region of the mitochondrial RNA polymerase of Plasmodium falciparum by Gupta, Ankit, Shrivastava, Deepti, Shakya, Anil Kumar, Gupta, Kirti, Pratap, JV, Habib, Saman

“…[Display omitted] •Phage-like polymerase PfmtRNAP targets to the Plasmodium mitochondrion and interacts with mtDNA.•PfmtRNAP interacts with PfKsgA1, the latter…”
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Asymmetric Organocatalytic Assembly of Oxindoles Fused with Spiro-3,4-dihydropyrans with Three Contiguous Stereocenters Consisting of Vicinal Quaternary Centers by Vishwanath, Manjunatha, Vinayagam, Poopathy, Gajulapalli, V Pratap Reddy, Kesavan, Venkitasamy

“…Diverse bispiro‐3,4‐dihydropyrans consisting of oxindole moieties with three contiguous chiral centers and vicinal quaternary stereocenters were synthesized…”
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In Situ FTIR Spectroscopic Monitoring of the Formation of the Arene Diazonium Salts and its Applications to the Heck-Matsuda Reaction by Reddy, K Sateesh, Siva, Bandi, Reddy, S Divya, Naresh, N Reddy, Pratap, T V, Rao, B Venkateswara, Hong, Yi-An, Kumar, B Vijaya, Raju, A Krishnam, Reddy, P Muralidhar, Hu, Anren

“…This study depicts the use of a fiber-optic coupled Fourier transform infrared spectroscopy-attenuated total reflection (FTIR-ATR) probe for the in-depth study…”
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Weed management practices in rice (Oryza sativa) + brahmi (Bacopa monnieri) intercropping system by JOSHI, NEESHU, PANDEY, SUNITA T, KUMAR, AJIT, SINGH, V PRATAP, GAUTAM, POONAM

“…A field study was carried out during two consecutive kharif seasons 2015–2016 at Norman E Borlaug Crop Research Centre, G B Pant University of Agriculture…”
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Polyphenolic enriched extract of Cassia glauca Lamk, improves streptozotocin-induced type-1 diabetes linked with partial insulin resistance in rats by Veerapur, V.P., Pratap, V., Thippeswamy, B.S., Marietta, P., Bansal, Punit, Kulkarni, P.V., Kulkarni, V.H.

“…Traditionally Cassia glauca (CG) has been used to treat diabetes. The study was undertaken to evaluate anti-diabetic and antioxidant activity of polyphenolic…”
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Stereoselective Formal Total Synthesis of (+)-Methynolide by Yadav, J. S, Pratap, T. V, Rajender, V

“…A highly stereoselective and convergent formal total synthesis of (+)-methynolide is described. The salient features of this synthesis have been the…”
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Design, synthesis, and in vitro biological evaluation of dehydroaripiprazole derivatives as antituberculosis agents and molecular docking study by Raja Sekhara Reddy, B., Pratap Reddy Gajulapalli, V., Madhu Rekha, Estharla, Siva Krishna, Vagolu, Sriram, Dharmarajan, Sudakar Babu, K, Kim, Eunha

“…•Aripiprazole derivatives were designed and synthesized and characterized.•Derivatives were defined as potent in vitro inhibitors of MTB H37Rv strain…”
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