Search Results - "Pratap, Siddharth"

Benzo(a)pyrene-induced cytotoxicity, cell proliferation, DNA damage, and altered gene expression profiles in HT-29 human colon cancer cells by Myers, Jeremy N., Harris, Kelly L., Rekhadevi, Perumalla V., Pratap, Siddharth, Ramesh, Aramandla

“…In the US alone, around 60,000 lives/year are lost to colon cancer. In order to study the mechanisms of colon carcinogenesis, in vitro model systems are…”
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piRNAs as Modulators of Disease Pathogenesis by Rayford, Kayla J, Cooley, Ayorinde, Rumph, Jelonia T, Arun, Ashutosh, Rachakonda, Girish, Villalta, Fernando, Lima, Maria F, Pratap, Siddharth, Misra, Smita, Nde, Pius N

“…Advances in understanding disease pathogenesis correlates to modifications in gene expression within different tissues and organ systems. In depth knowledge…”
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Role of oral and gut microbiome in nitric oxide-mediated colon motility by Walker, Miriam Y., Pratap, Siddharth, Southerland, Janet H., Farmer-Dixon, Cherae M., Lakshmyya, Kesavalu, Gangula, Pandu R.

“…Periodontal disease (PD), a severe form of gum disease, is among the most prevalent chronic infection in humans and is associated with complex microbial…”
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Multidrug resistant Acinetobacter baumannii: a descriptive study in a city hospital by Dent, Lemuel L, Marshall, Dana R, Pratap, Siddharth, Hulette, Robert B

“…Multidrug resistant Acinetobacter baumannii, (MRAB) is an important cause of hospital acquired infection. The purpose of this study is to determine the risk…”
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Metformin regulates multiple signaling pathways within castration-resistant human prostate cancer cells by Olokpa, Emuejevoke, Mandape, Sammed N, Pratap, Siddharth, Stewart, La Monica V

“…Abstract Background The biguanide metformin has been shown to not only reduce circulating glucose levels but also suppress in vitro and in vivo growth of…”
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Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells by Arun, Ashutosh, Rayford, Kayla J, Cooley, Ayorinde, Rana, Tanu, Rachakonda, Girish, Villalta, Fernando, Pratap, Siddharth, Lima, Maria F, Sheibani, Nader, Nde, Pius N

“…The protozoan parasite, Trypanosoma cruzi, causes severe morbidity and mortality in afflicted individuals. Approximately 30% of T. cruzi infected individuals…”
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Depletion of the aryl hydrocarbon receptor in MDA-MB-231 human breast cancer cells altered the expression of genes in key regulatory pathways of cancer by Goode, Gennifer, Pratap, Siddharth, Eltom, Sakina E

“…The aryl hydrocarbon receptor (AhR), a transcription factor that is best known for its role in mediating the toxic responses elicited by poly aromatic…”
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HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network by Kaddour, Hussein, Kopcho, Steven, Lyu, Yuan, Shouman, Nadia, Paromov, Victor, Pratap, Siddharth, Dash, Chandravanu, Kim, Eun-Young, Martinson, Jeremy, McKay, Heather, Epeldegui, Marta, Margolick, Joseph B., Stapleton, Jack T., Okeoma, Chioma M.

“…Background Extracellular vesicles (EVs) are regulators of cell–cell interactions and mediators of horizontal transfer of bioactive molecules between cells…”
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Oral microbiome associated with differential ratios of Porphyromonas gingivalis and Streptococcus cristatus by Wang, Qingguo, Wang, Bing-Yan, Pratap, Siddharth, Xie, Hua

“…Periodontitis has recently been defined as a dysbiotic disease caused by an imbalanced oral microbiota. The transition from commensal microbial communities to…”
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The Proteomic Analysis of Cancer-Related Alterations in the Human Unfoldome by Paromov, Victor, Uversky, Vladimir N, Cooley, Ayorinde, Liburd, 2nd, Lincoln E, Mukherjee, Shyamali, Na, Insung, Dayhoff, 2nd, Guy W, Pratap, Siddharth

“…Many proteins lack stable 3D structures. These intrinsically disordered proteins (IDPs) or hybrid proteins containing ordered domains with intrinsically…”
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Identification of Specific Oral and Gut Pathogens in Full Thickness Colon of Colitis Patients: Implications for Colon Motility by Dinakaran, Vasudevan, Mandape, Sammed N, Shuba, Kristina, Pratap, Siddharth, Sakhare, Shruti S, Tabatabai, Mohammad Ali, Smoot, Duane T, Farmer-Dixon, Cherae M, Kesavalu, Lakshmyya N, Adunyah, Samuel Evans, Southerland, Janet Hayes, Gangula, Pandu R

“…Impaired colon motility is one of the leading problems associated with inflammatory bowel disease (IBD). An expanding body of evidence supports the role of…”
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Trypanosoma brucei Tim50 Possesses PAP Activity and Plays a Critical Role in Cell Cycle Regulation and Parasite Infectivity by Tripathi, Anuj, Singha, Ujjal K, Cooley, Ayorinde, Gillyard, Taneisha, Krystofiak, Evan, Pratap, Siddharth, Davis, Jamaine, Chaudhuri, Minu

“…Trypanosoma brucei, the infective agent for African trypanosomiasis, possesses a homologue of the translocase of the mitochondrial inner membrane 50 (TbTim50)…”
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Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection by Rayford, Kayla J, Cooley, Ayorinde, Arun, Ashutosh, Rachakonda, Girish, Kleschenko, Yulia, Villalta, Fernando, Pratap, Siddharth, Lima, Maria F, Nde, Pius N

“…dysregulates the gene expression profile of primary human cardiomyocytes (PHCM) during the early phase of infection through a mechanism which remains to be…”
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Wind energy conversion with a variable-ratio gearbox: design and analysis by Hall, John F., Mecklenborg, Christine A., Chen, Dongmei, Pratap, Siddharth B.

“…Variable-speed wind turbines are able to adapt to low wind speeds and therefore have greater efficiency than fixed-speed turbines during partial-load…”
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Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells by Arun, Ashutosh, Rayford, Kayla J, Cooley, Ayorinde, Rachakonda, Girish, Villalta, Fernando, Pratap, Siddharth, Lima, Maria F, Sheibani, Nader, Nde, Pius N

“…The protozoan parasite is the causative agent of Chagas disease. This neglected tropical disease causes severe morbidity and mortality in endemic regions…”
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The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network by Leppig, Kathleen A., Kulchak Rahm, Alanna, Appelbaum, Paul, Aufox, Sharon, Bland, Harris T., Buchanan, Adam, Christensen, Kurt D., Chung, Wendy K., Clayton, Ellen Wright, Crosslin, David, Denny, Josh, DeVange, Shannon, Gordon, Adam, Green, Robert C., Hakonarson, Hakon, Harr, Margaret H., Henrikson, Nora, Hoell, Christin, Holm, Ingrid A., Kullo, Iftikhar J., Jarvik, Gail P., Lammers, Philip E., Larson, Eric B., Lindor, Noralane M., Marasa, Maddalena, Myers, Melanie F., Perez, Emma, Peterson, Josh F., Pratap, Siddharth, Prows, Cynthia A., Ralston, James D., Rasouly, Hila Milo, Roden, Dan M., Sharp, Richard R., Singh, Rajbir, Shaibi, Gabriel, Smith, Maureen E., Sturm, Amy, Thiese, Heidi A., Van Driest, Sara L., Williams, Janet, Williams, Marc S., Wynn, Julia, Blout Zawatsky, Carrie L., Wiesner, Georgia L.

“…The goal of Electronic Medical Records and Genomics (eMERGE) Phase III Network was to return actionable sequence variants to 25,084 consenting participants…”
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Trypanosoma cruzi dysregulates expression profile of piRNAs in primary human cardiac fibroblasts during early infection phase by Rayford, Kayla J, Cooley, Ayorinde, Strode, Anthony W, Osi, Inmar, Arun, Ashutosh, Lima, Maria F, Misra, Smita, Pratap, Siddharth, Nde, Pius N

“…, the etiological agent of Chagas Disease, causes severe morbidity, mortality, and economic burden worldwide. Though originally endemic to Central and South…”
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Phospho-proteomic analysis of primary human colon epithelial cells during the early Trypanosoma cruzi infection phase by Suman, Shankar, Rachakonda, Girish, Mandape, Sammed N, Sakhare, Shruti S, Villalta, Fernando, Pratap, Siddharth, Lima, Maria F, Nde, Pius N

“…The protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, causes severe morbidity and mortality in afflicted individuals. About 30% of…”
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Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi by Udoko, Aniekanabassi N, Johnson, Candice A, Dykan, Andrey, Rachakonda, Girish, Villalta, Fernando, Mandape, Sammed N, Lima, Maria F, Pratap, Siddharth, Nde, Pius N

“…The molecular mechanisms of Trypanosoma cruzi induced cardiac fibrosis remains to be elucidated. Primary human cardiomyoctes (PHCM) exposed to invasive T…”
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Identification of MAGEC2/CT10 as a High Calcium-Inducible Gene in Triple-Negative Breast Cancer by Beasley, Heather K, Widatalla, Sarrah E, Whalen, Diva S, Williams, Stephen D, Korolkova, Olga Y, Namba, Clementine, Pratap, Siddharth, Ochieng, Josiah, Sakwe, Amos M

“…The expression of the melanoma/cancer-testis antigen MAGEC2/CT10 is restricted to germline cells, but like most cancer-testis antigens, it is frequently…”
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