Search Results - "Prasolov, V. S."

Replication protein A modulates the activity of human telomerase in vitro by Rubtsova, M. P, Skvortsov, D. A, Petruseva, I. O, Lavrik, O. I, Spirin, P. V, Prasolov, V. S, Kisseljov, F. L, Dontsova, O. A

“…Our aim was to investigate how replication protein A (RPA) in a wide range of concentration can regulate the activity of human telomerase. We used an in vitro…”
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Baculovirus vectors for efficient gene delivery and expression in mammalian cells by Koroleva, N. N, Spirin, P. V, Timokhova, A. V, Rubtzov, P. M, Kochetkov, S. N, Prasolov, V. S, Beljelarskaya, S. N

“…Baculovirus expression vectors are extensively used for the delivery of foreign genes and expression of recombinant proteins in insect and mammalian cells…”
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Altered expression of the SEMA3B gene in epithelial tumors by Pronina, I. V, Loginov, V. I, Prasolov, V. S, Klimov, E. A, Khodyrev, D. S, Kazubskaya, T. P, Gar'kavtseva, R. F, Sulimova, G. E, Braga, E. A

“…Tumor-specific expression downregulation may be indicative of a gene's involvement in tumor suppression. For instance, SEMA3B mRNA levels are decreased in many…”
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Lentiviral vector-based assay system for quantitative detection of intracellular translocations of recombinant proteins by Chumakov, S. P, Ilyinskaya, G. V, Kravchenko, J. E, Frolova, E. I, Prasolov, V. S, Chumakov, P. M

“…An enzymatic assay system was developed to quantify the distribution of recombinant proteins over various cell structures. The system takes advantage of…”
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The role of HCV e2 protein glycosylation in functioning of virus envelope proteins in insect and Mammalian cells by Orlova, O V, Drutsa, V L, Spirin, P V, Prasolov, V S, Rubtsov, P M, Kochetkov, S N, Beljelarskaya, S N

“…The hepatitis C virus (HCV) envelope proteins E1 and E2, being virion components, are involved in the formation of infectious particles in infected cells. The…”
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Functional characterization of two novel splicing mutations of glucokinase gene associated with maturity-onset diabetes of the young type 2 (MODY2) by Igudin, E. L., Spirin, P. V., Prasolov, V. S., Zubkova, N. A., Petryaikina, E. E., Tyul’pakov, A. N., Rubtsov, P. M.

“…Two novel mutations in the glucokinase gene ( GCK ) have been identified in patients with maturity-onset diabetes of the young type-2 (MODY2), i.e., a C-for-G…”
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Expression of FLT3-ITD oncogene confers mice progenitor B-cells BAF3 sensitivity to the ribonuclease binase cytotoxic action by Mit'kevich, V A, Orlova, N N, Petrushanko, I Iu, Simonenko, O V, Spirin, P V, Prokofeva, M M, Gornostaeva, A S, Stocking, C, Makarov, A A, Prasolov, V S

“…Acute myeloid leukemia is the most common acute leukemia affecting adults, and its incidence increases with age. Along with chromosomal translocations in…”
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Dynamics of penetration of “Rigid” nanostructures of double-stranded DNA complexed with gadolinium into CHO cells by Popenko, V. I., Leonova, O. G., Salyanov, V. I., Orlova, N. N., Spirin, P. V., Prasolov, V. S., Evdokimov, Yu. M.

“…Currently, neutron capture therapy is a promising cancer treatment. This method is based on the reaction of thermal neutron capture by some nonradioactive…”
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Modulation of activated oncogene c-kit expression with RNA-interference by Spirin, P. V., Nikitenko, N. A., Lebedev, T. D., Rubtsov, P. M., Stocking, C., Prasolov, V. S.

“…Overexpression of oncogene c-kit is detected in 80% patients with acute myeloid leukemia (AML). A transgenic model cell line expressing oncogene c-kit was…”
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Dynamics of penetration of "solid" nanoconstructions based on double-stranded DNA complexed with gadolinium into CHO cells by Popenko, V I, Leonova, O G, Salianov, V I, Orlova, N N, Spirin, P V, Prasolov, V S, Evdokimov, Iu M

“…Currently, neutron capture therapy is a promising cancer treatment. This method is based on the reaction of the thermal neutron capture by some non-radioactive…”
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RNA interference and deep sequencing as tools for identifying new genes involved in leukemogenesis by Lebedev, T. D., Spirin, P. V., Orlova, N. N., Kudryavtseva, A. V., Melnikova, N. V., Speranskaya, A. S., Prasolov, V. S.

“…The establishment of the molecular mechanisms of occurrence and progression of oncological diseases and the development of effective tools to combat them is an…”
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Influence of antioxidants on NO-dependent induction of heme oxygenase-1 in U937 monocytes by Litvinov, D. Yu, Prasolov, V. S., Bouton, S., Drapier, J. C., Turpaev, K. T.

“…Thiol antioxidants are known to inhibit the nitric oxide-dependent induction of the hemoxygenase-1 gene (HOX-1). To estimate the degree to which the inhibitory…”
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Role of N-linked glycans of HCV glycoprotein E1 in folding of structural proteins and formation of viral particles by Orlova, O. V., Drutsa, V. L., Spirin, P. V., Popenko, V. I., Prasolov, V. S., Rubtsov, P. M., Kochetkov, S. N., Belzhelarskaya, S. N.

“…Envelope proteins E1 and E2 of the hepatitis C virus (HCV) play a major role in the life cycle of a virus. These proteins are the main components of the virion…”
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Role of N-linked glycans in HCV glycoprotein E1 in the folding of structural proteins and formation viral particles by Orlova, O V, Drutsa, V L, Spirin, P V, Popenko, V I, Prasolov, V S, Rubtsov, P M, Kochetkov, S N, Belzhelarskaia, S N

“…Envelope proteins of HCV play a major role in virus lifecycle. These proteins are main components of the virion. They are involved in virus assembly. Envelope…”
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Coordinated interaction of multifunctional members of the p53 family determines many key processes in multicellular organisms by Vilgelm, A. E, Zaika, A. I, Prassolov, V. S

“…For the first time, p53 was found in complex with the viral large T-antigen in cells transformed with the small DNA virus SV40. p53 cDNA was cloned in the…”
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Replication-competent γ-retrovirus Mo-MuLV expressing green fluorescent protein gene as an efficient tool for screening of inhibitors of retroviruses that use heparan sulfate as the primary cell receptor by Stepanov, O A, Prokof'eva, M M, Stocking, C, Varlamov, V P, Levov, A N, Vikhoreva, G A, Spirin, P V, Mikhaĭlov, S N, Prasolov, V S

“…The effect of sulfated polysaccharides on the efficiency of infection of mouse embryonic fibroblast cell lines SC-1 and NIH-3T3 by replication-competent…”
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The Effect of Catalase on the Expression of Nitric Oxide-dependent Genes in Primary Chondrocytes by Litvinov, D Yu, Dubovaya, V I, Vasil'ev, M G, Lekishvili, M V, Prasolov, V S, Turpaev, K T

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Construction of Chimeric Tumor Suppressor p53 Resistant to the Dominant-Negative Interaction with p53 Mutants by Almazov, V P, Morgunkova, A A, Kalinin, V N, Kopnin, B P, Prasolov, V S, Chumakov, P M

“…A chimeric p53 cDNA was constructed so that the fragment coding for 39 residues of the chicken p53 tetramerization domain replaced the corresponding region of…”
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New furano- and pyrrolo[2,3-d]pyrimidine nucleosides and their 5′-O-triphosphates: Synthesis and biological properties by Ivanov, M. A., Ivanov, A. V., Krasnitskaya, I. A., Smirnova, O. A., Karpenko, I. L., Belanov, E. F., Prasolov, V. S., Tunitskaya, V. L., Alexandrova, L. A.

“…Bicyclic furano[2,3- d ]pyrimidine ribonucleosides were synthesized by Pd(0)-and CuI-catalyzed coupling of 5-iodouridine with terminal alkynes. The treatment…”
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Receptor-independent spread of the measles virus is unique to neurons and involves fusion of synaptic membranes by Makhortova, N R, Rall, G F, Prasolov, V S

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