Search Results - "Prasanth, Supriya G"

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    Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB by Tripathi, Vidisha, Shen, Zhen, Chakraborty, Arindam, Giri, Sumanprava, Freier, Susan M, Wu, Xiaolin, Zhang, Yongqing, Gorospe, Myriam, Prasanth, Supriya G, Lal, Ashish, Prasanth, Kannanganattu V

    Published in PLoS genetics (01-03-2013)
    “…The long noncoding MALAT1 RNA is upregulated in cancer tissues and its elevated expression is associated with hyper-proliferation, but the underlying mechanism…”
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    Optical measurement of cycle-dependent cell growth by Mir, Mustafa, Wang, Zhuo, Shen, Zhen, Bednarz, Michael, Bashir, Rashid, Golding, Ido, Prasanth, Supriya G, Popescu, Gabriel

    “…Determining the growth patterns of single cells offers answers to some of the most elusive questions in contemporary cell biology: how cell growth is regulated…”
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    Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer by Jadaliha, Mahdieh, Zong, Xinying, Malakar, Pushkar, Ray, Tania, Singh, Deepak K, Freier, Susan M, Jensen, Tor, Prasanth, Supriya G, Karni, Rotem, Ray, Partha S, Prasanth, Kannanganattu V

    Published in Oncotarget (28-06-2016)
    “…MALAT1 (metastasis associated lung adenocarcinoma transcript1) is a conserved long non-coding RNA, known to regulate gene expression by modulating…”
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    Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization by Prasanth, Supriya G., Shen, Zhen, Prasanth, Kannanganattu V., Stillman, Bruce

    “…The origin recognition complex (ORC) is a DNA replication initiator protein also known to be involved in diverse cellular functions including gene silencing,…”
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    Chromatin's Influence on Pre-Replication Complex Assembly and Function by Ahmad, Hina, Chetlangia, Neha, Prasanth, Supriya G

    Published in Biology (Basel, Switzerland) (27-02-2024)
    “…In all eukaryotes, the initiation of DNA replication requires a stepwise assembly of factors onto the origins of DNA replication. This is pioneered by the…”
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    Distinct structural bases for sequence-specific DNA binding by mammalian BEN domain proteins by Zheng, Luqian, Liu, Jingjing, Niu, Lijie, Kamran, Mohammad, Yang, Ally W H, Jolma, Arttu, Dai, Qi, Hughes, Timothy R, Patel, Dinshaw J, Zhang, Long, Prasanth, Supriya G, Yu, Yang, Ren, Aiming, Lai, Eric C

    Published in Genes & development (01-02-2022)
    “…The BEN domain is a recently recognized DNA binding module that is present in diverse metazoans and certain viruses. Several BEN domain factors are known as…”
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    Orc1 Controls Centriole and Centrosome Copy Number in Human Cells by Hemerly, Adriana S, Prasanth, Supriya G, Siddiqui, Khalid, Stillman, Bruce

    “…Centrosomes, each containing a pair of centrioles, organize microtubules in animal cells, particularly during mitosis. DNA and centrosomes are normally…”
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    PCNA-mediated stabilization of E3 ligase RFWD3 at the replication fork is essential for DNA replication by Lin, Yo-Chuen, Wang, Yating, Hsu, Rosaline, Giri, Sumanprava, Wopat, Susan, Arif, Mariam K., Chakraborty, Arindam, Prasanth, Kannanganattu V., Prasanth, Supriya G.

    “…RING finger and WD repeat domain-containing protein 3 (RFWD3) is an E3 ligase known to facilitate homologous recombination by removing replication protein A…”
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    LncRNA-mediated regulation of SOX9 expression in basal subtype breast cancer cells by Tariq, Aamira, Hao, Qinyu, Sun, Qinyu, Singh, Deepak K, Jadaliha, Mahdieh, Zhang, Yang, Chetlangia, Neha, Ma, Jian, Holton, Sarah E, Bhargava, Rohit, Lal, Ashish, Prasanth, Supriya G, Prasanth, Kannanganattu V

    Published in RNA (Cambridge) (01-02-2020)
    “…Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer (BC) subtypes with a poor prognosis and high recurrence rate. Recent studies…”
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    A WD-Repeat Protein Stabilizes ORC Binding to Chromatin by Shen, Zhen, Sathyan, Kizhakke M., Geng, Yijie, Zheng, Ruiping, Chakraborty, Arindam, Freeman, Brian, Wang, Fei, Prasanth, Kannanganattu V., Prasanth, Supriya G.

    Published in Molecular cell (08-10-2010)
    “…Origin recognition complex (ORC) plays critical roles in the initiation of DNA replication and cell-cycle progression. In metazoans, ORC associates with origin…”
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    BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase by Khan, Abid, Sumanprava Giri, Yating Wang, Arindam Chakraborty, Archit K. Ghosh, Aparna Anantharaman, Vasudha Aggarwal, Kizhakke M. Sathyan, Taekjip Ha, Kannanganattu V. Prasanth, Supriya G. Prasanth

    “…Ribosome biogenesis dictates the translational capacity of cells. Several mechanisms establish and maintain transcriptional output from eukaryotic ribosomal…”
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    Dynamic Association of ORCA with Prereplicative Complex Components Regulates DNA Replication Initiation by Shen, Zhen, Chakraborty, Arindam, Jain, Ankur, Giri, Sumanprava, Ha, Taekjip, Prasanth, Kannanganattu V., Prasanth, Supriya G.

    Published in Molecular and Cellular Biology (01-08-2012)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Orc2 protects ORCA from ubiquitin-mediated degradation by Shen, Zhen, Prasanth, Supriya G.

    Published in Cell cycle (Georgetown, Tex.) (01-10-2012)
    “…Origin recognition complex (ORC) is highly dynamic, with several ORC subunits getting posttranslationally modified by phosphorylation or ubiquitination in a…”
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    Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA by Anantharaman, Aparna, Jadaliha, Mahdieh, Tripathi, Vidisha, Nakagawa, Shinichi, Hirose, Tetsuro, Jantsch, Michael F., Prasanth, Supriya G., Prasanth, Kannanganattu V.

    Published in Scientific reports (26-09-2016)
    “…Paraspeckles are sub-nuclear domains that are nucleated by long noncoding RNA Neat1 . While interaction of protein components of paraspeckles and Neat1 is…”
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