Search Results - "Prasanna Jagannathan"

Malaria in 2022: Increasing challenges, cautious optimism by Jagannathan, Prasanna, Kakuru, Abel

“…Malaria cases and deaths remain unacceptably high and are resurgent in several settings, though recent developments inspire optimism. This includes the…”
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How does malaria in pregnancy impact malaria risk in infants? by Jagannathan, Prasanna

“…Malaria in pregnancy not only exerts profound negative consequences on the health of the mother and developing fetus, but may also alter the risk of malaria…”
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Immunity after SARS-CoV-2 infections by Jagannathan, Prasanna, Wang, Taia T.

“…T cell responses probably play important roles in the control of SARS-CoV-2 infection, but they have been relatively understudied. Data now suggest that the…”
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New-onset IgG autoantibodies in hospitalized patients with COVID-19 by Chang, Sarah Esther, Feng, Allan, Meng, Wenzhao, Apostolidis, Sokratis A., Mack, Elisabeth, Artandi, Maja, Barman, Linda, Bennett, Kate, Chakraborty, Saborni, Chang, Iris, Cheung, Peggie, Chinthrajah, Sharon, Dhingra, Shaurya, Do, Evan, Finck, Amanda, Gaano, Andrew, Geßner, Reinhard, Giannini, Heather M., Gonzalez, Joyce, Greib, Sarah, Gündisch, Margrit, Hsu, Alex Ren, Kuo, Alex, Manohar, Monali, Mao, Rong, Neeli, Indira, Neubauer, Andreas, Oniyide, Oluwatosin, Powell, Abigail E., Puri, Rajan, Renz, Harald, Schapiro, Jeffrey, Weidenbacher, Payton A., Wittman, Richard, Ahuja, Neera, Chung, Ho-Ryun, Jagannathan, Prasanna, James, Judith A., Kim, Peter S., Meyer, Nuala J., Nadeau, Kari C., Radic, Marko, Robinson, William H., Singh, Upinder, Wang, Taia T., Wherry, E. John, Skevaki, Chrysanthi, Luning Prak, Eline T., Utz, Paul J.

“…COVID-19 is associated with a wide range of clinical manifestations, including autoimmune features and autoantibody production. Here we develop three protein…”
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Type I regulatory T cells in malaria: of mice and men by Nideffer, Jason, Jagannathan, Prasanna

“…Type I regulatory T (Tr1) cells are a population of regulatory CD4+ T cells implicated in the suppression of pathological immune responses across multiple…”
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Peginterferon Lambda-1a for treatment of outpatients with uncomplicated COVID-19: a randomized placebo-controlled trial by Jagannathan, Prasanna, Andrews, Jason R., Bonilla, Hector, Hedlin, Haley, Jacobson, Karen B., Balasubramanian, Vidhya, Purington, Natasha, Kamble, Savita, de Vries, Christiaan R., Quintero, Orlando, Feng, Kent, Ley, Catherine, Winslow, Dean, Newberry, Jennifer, Edwards, Karlie, Hislop, Colin, Choong, Ingrid, Maldonado, Yvonne, Glenn, Jeffrey, Bhatt, Ami, Blish, Catherine, Wang, Taia, Khosla, Chaitan, Pinsky, Benjamin A., Desai, Manisha, Parsonnet, Julie, Singh, Upinder

“…Type III interferons have been touted as promising therapeutics in outpatients with coronavirus disease 2019 (COVID-19). We conducted a randomized,…”
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SARS-CoV-2 Antiviral Therapy by Tao, Kaiming, Tzou, Philip L, Nouhin, Janin, Bonilla, Hector, Jagannathan, Prasanna, Shafer, Robert W

“…The development of effective antiviral therapy for COVID-19 is critical for those awaiting vaccination, as well as for those who do not respond robustly to…”
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Proinflammatory IgG Fc structures in patients with severe COVID-19 by Chakraborty, Saborni, Gonzalez, Joseph, Edwards, Karlie, Mallajosyula, Vamsee, Buzzanco, Anthony S., Sherwood, Robert, Buffone, Cindy, Kathale, Nimish, Providenza, Susan, Xie, Markus M., Andrews, Jason R., Blish, Catherine A., Singh, Upinder, Dugan, Haley, Wilson, Patrick C., Pham, Tho D., Boyd, Scott D., Nadeau, Kari C., Pinsky, Benjamin A., Zhang, Sheng, Memoli, Matthew J., Taubenberger, Jeffery K., Morales, Tasha, Schapiro, Jeffrey M., Tan, Gene S., Jagannathan, Prasanna, Wang, Taia T.

“…Severe acute respiratory syndrome coronavirus 2 infections can cause coronavirus disease 2019 (COVID-19), which manifests with a range of severities from mild…”
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Editorial: Immune tolerance and human malaria by Dobbs, Katherine Rose, Jagannathan, Prasanna, Dechavanne, Celia

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Immune mechanisms underlying COVID-19 pathology and post-acute sequelae of SARS-CoV-2 infection (PASC) by Mohandas, Sindhu, Jagannathan, Prasanna, Henrich, Timothy J, Sherif, Zaki A, Bime, Christian, Quinlan, Erin, Portman, Michael A, Gennaro, Marila, Rehman, Jalees

“…With a global tally of more than 500 million cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections to date, there are growing…”
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Standardized preservation, extraction and quantification techniques for detection of fecal SARS-CoV-2 RNA by Natarajan, Aravind, Han, Alvin, Zlitni, Soumaya, Brooks, Erin F., Vance, Summer E., Wolfe, Marlene, Singh, Upinder, Jagannathan, Prasanna, Pinsky, Benjamin A., Boehm, Alexandria, Bhatt, Ami S.

“…Patients with COVID-19 shed SARS-CoV-2 RNA in stool, sometimes well after their respiratory infection has cleared. This may be significant for patient health,…”
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Dihydroartemisinin–Piperaquine for the Prevention of Malaria in Pregnancy by Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary K, Natureeba, Paul, Awori, Patricia, Nakalembe, Miriam, Opira, Bishop, Olwoch, Peter, Ategeka, John, Nayebare, Patience, Clark, Tamara D, Feeney, Margaret E, Charlebois, Edwin D, Rizzuto, Gabrielle, Muehlenbachs, Atis, Havlir, Diane V, Kamya, Moses R, Dorsey, Grant

“…Malaria causes complications during pregnancy, and its prevention is more challenging in the setting of drug-resistant parasites. This trial from Uganda, where…”
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Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection by Natarajan, Aravind, Zlitni, Soumaya, Brooks, Erin F, Vance, Summer E, Dahlen, Alex, Hedlin, Haley, Park, Ryan M, Han, Alvin, Schmidtke, Danica T, Verma, Renu, Jacobson, Karen B, Parsonnet, Julie, Bonilla, Hector F, Singh, Upinder, Pinsky, Benjamin A, Andrews, Jason R, Jagannathan, Prasanna, Bhatt, Ami S

“…COVID-19 manifests with respiratory, systemic, and gastrointestinal (GI) symptoms. SARS-CoV-2 RNA is detected in respiratory and fecal samples, and recent…”
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γδ T Cells in Antimalarial Immunity: New Insights Into Their Diverse Functions in Protection and Tolerance by Dantzler, Kathleen W, Jagannathan, Prasanna

“…Uniquely expressing diverse innate-like and adaptive-like functions, γδ T cells exist as specialized subsets, but are also able to adapt in response to…”
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Exposure to pesticides in utero impacts the fetal immune system and response to vaccination in infancy by Prahl, Mary, Odorizzi, Pamela, Gingrich, David, Muhindo, Mary, McIntyre, Tara, Budker, Rachel, Jagannathan, Prasanna, Farrington, Lila, Nalubega, Mayimuna, Nankya, Felistas, Sikyomu, Esther, Musinguzi, Kenneth, Naluwu, Kate, Auma, Ann, Kakuru, Abel, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Feeney, Margaret E.

“…The use of pesticides to reduce mosquito vector populations is a cornerstone of global malaria control efforts, but the biological impact of most pesticides on…”
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Antibodies elicited by SARS-CoV-2 infection or mRNA vaccines have reduced neutralizing activity against Beta and Omicron pseudoviruses by Sievers, Benjamin L, Chakraborty, Saborni, Xue, Yong, Gelbart, Terri, Gonzalez, Joseph C, Cassidy, Arianna G, Golan, Yarden, Prahl, Mary, Gaw, Stephanie L, Arunachalam, Prabhu S, Blish, Catherine A, Boyd, Scott D, Davis, Mark M, Jagannathan, Prasanna, Nadeau, Kari C, Pulendran, Bali, Singh, Upinder, Scheuermann, Richard H, Frieman, Matthew B, Vashee, Sanjay, Wang, Taia T, Tan, Gene S

“…Multiple severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants that have mutations associated with increased transmission and antibody escape…”
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Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children by Wallender, Erika, Ali, Ali Mohamed, Hughes, Emma, Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary Kakuru, Opira, Bishop, Whalen, Meghan, Huang, Liusheng, Duvalsaint, Marvin, Legac, Jenny, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.

“…Intermittent preventive treatment (IPT) with dihydroartemisinin-piperaquine (DP) is highly protective against malaria in children, but is not standard in…”
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Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure by Rodriguez-Barraquer, Isabel, Arinaitwe, Emmanuel, Jagannathan, Prasanna, Kamya, Moses R, Rosenthal, Phillip J, Rek, John, Dorsey, Grant, Nankabirwa, Joaniter, Staedke, Sarah G, Kilama, Maxwell, Drakeley, Chris, Ssewanyana, Isaac, Smith, David L, Greenhouse, Bryan

“…Fundamental gaps remain in our understanding of how immunity to malaria develops. We used detailed clinical and entomological data from parallel cohort studies…”
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Publisher Correction: Standardized preservation, extraction and quantification techniques for detection of fecal SARS-CoV-2 RNA by Natarajan, Aravind, Han, Alvin, Zlitni, Soumaya, Brooks, Erin F., Vance, Summer E., Wolfe, Marlene, Singh, Upinder, Jagannathan, Prasanna, Pinsky, Benjamin A., Boehm, Alexandria, Bhatt, Ami S.

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Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens by Reyes, Raphael A, Turner, Louise, Ssewanyana, Isaac, Jagannathan, Prasanna, Feeney, Margaret E, Lavstsen, Thomas, Greenhouse, Bryan, Bol, Sebastiaan, Bunnik, Evelien M

“…Plasmodium falciparum infections elicit strong humoral immune responses to two main groups of antigens expressed by blood-stage parasites: merozoite antigens…”
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